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Jack D Chan
Jack D Chan
Peter MacCallum Cancer Centre, University of Melbourne
Verified email at petermac.org - Homepage
Title
Cited by
Cited by
Year
Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity
J Lai, S Mardiana, IG House, K Sek, MA Henderson, L Giuffrida, ...
Nature immunology 21 (8), 914-926, 2020
1402020
Cellular networks controlling T cell persistence in adoptive cell therapy
JD Chan, J Lai, CY Slaney, A Kallies, PA Beavis, PK Darcy
Nature Reviews Immunology 21 (12), 769-784, 2021
1152021
MAIT cells regulate NK cell-mediated tumor immunity
EV Petley, HF Koay, MA Henderson, K Sek, KL Todd, SP Keam, J Lai, ...
Nature communications 12 (1), 4746, 2021
512021
Genetic redirection of T cells for the treatment of pancreatic cancer
AI Ali, AJ Oliver, T Samiei, JD Chan, MH Kershaw, CY Slaney
Frontiers in oncology 9, 56, 2019
472019
Tissue‐specific tumor microenvironments influence responses to immunotherapies
AJ Oliver, AS Davey, SP Keam, S Mardiana, JD Chan, B von Scheidt, ...
Clinical & translational immunology 8 (11), e1094, 2019
272019
Enterotoxins can support CAR T cells against solid tumors
B von Scheidt, M Wang, AJ Oliver, JD Chan, MK Jana, AI Ali, F Clow, ...
Proceedings of the National Academy of Sciences 116 (50), 25229-25235, 2019
242019
Enhancing chimeric antigen receptor T‐cell immunotherapy against cancer using a nanoemulsion‐based vaccine targeting cross‐presenting dendritic cells
JD Chan, B von Scheidt, B Zeng, AJ Oliver, AS Davey, AI Ali, R Thomas, ...
Clinical & translational immunology 9 (7), e1157, 2020
222020
A histone deacetylase inhibitor, panobinostat, enhances chimeric antigen receptor T-cell antitumor effect against pancreatic cancer
AI Ali, M Wang, B von Scheidt, PM Dominguez, AJ Harrison, DGM Tantalo, ...
Clinical Cancer Research 27 (22), 6222-6234, 2021
192021
p38 Kinase: a key target for driving potent T cells for adoptive immunotherapy
JD Chan, PA Beavis, PK Darcy
Cancer cell 37 (6), 756-758, 2020
42020
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity
IG House, EB Derrick, K Sek, AXY Chen, J Li, J Lai, KL Todd, I Munoz, ...
Cell reports 42 (8), 2023
32023
FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy
JD Chan, CM Scheffler, I Munoz, K Sek, JN Lee, YK Huang, KM Yap, ...
Nature, 1-10, 2024
12024
Chimeric antigen receptor T cell therapies for thoracic cancers—challenges and opportunities
JD Chan, AJ Harrison, PK Darcy, MH Kershaw, CY Slaney
Journal of Thoracic Disease 12 (8), 4510, 2020
12020
Tumor-site directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors
P Darcy, K Sek, A Chen, T Cole, J Armitage, J Tong, KM Yap, I Munoz, ...
2024
A Rare Cell State Underpins Diverse Mechanisms of Adaptive Resistance to CAR T-Cell Therapy in B-Cell Acute Lymphoblastic Leukemia
JA Kuzich, L Talarmain, D Vassiliadis, AA Guirguis, JD Chan, PA Beavis, ...
Blood 142, 887, 2023
2023
Overexpression of FOXO1 enhances CAR T cell polyfunctionality, metabolic fitness and efficacy against solid tumors
P Beavis, P Darcy, J Lai, J Chan, K Sek, C Scheffler, I Munoz, YK Huang, ...
2023
Enhancing CAR T cell therapy by enabling their interaction with antigen-presenting cells
CY Slaney, P Wang, JD Chan, PK Darcy, MH Kershaw
EUROPEAN JOURNAL OF IMMUNOLOGY 49, 1711-1711, 2019
2019
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