|Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer|
Z Li, AC Bishop, M Alyamani, JA Garcia, R Dreicer, D Bunch, J Liu, ...
Nature 523 (7560), 347-351, 2015
|Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation|
Z Li, F Nie, S Wang, L Li
Proceedings of the National Academy of Sciences 108 (8), 3116-3123, 2011
|Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy|
Z Li, M Alyamani, J Li, K Rogacki, M Abazeed, SK Upadhyay, SP Balk, ...
Nature 533 (7604), 547-551, 2016
|Smurf1-mediated Lys29-linked nonproteolytic polyubiquitination of axin negatively regulates Wnt/β-catenin signaling|
C Fei, Z Li, C Li, Y Chen, Z Chen, X He, L Mao, X Wang, R Zeng, L Li
Molecular and cellular biology 33 (20), 4095-4105, 2013
|Aberrant corticosteroid metabolism in tumor cells enables GR takeover in enzalutamide resistant prostate cancer|
J Li, M Alyamani, A Zhang, KH Chang, M Berk, Z Li, Z Zhu, M Petro, ...
Elife 6, e20183, 2017
|Steroidogenic metabolism of galeterone reveals a diversity of biochemical activities|
M Alyamani, Z Li, M Berk, J Li, J Tang, S Upadhyay, RJ Auchus, N Sharifi
Cell chemical biology 24 (7), 825-832. e6, 2017
|Smad6 promotes neuronal differentiation in the intermediate zone of the dorsal neural tube by inhibition of the Wnt/β-catenin pathway|
Z Xie, Y Chen, Z Li, G Bai, Y Zhu, R Yan, F Tan, YG Chen, F Guillemot, ...
Proceedings of the National Academy of Sciences 108 (29), 12119-12124, 2011
|TAB2 scaffolds TAK1 and NLK in repressing canonical Wnt signaling|
M Li, H Wang, T Huang, J Wang, Y Ding, Z Li, J Zhang, L Li
Journal of Biological Chemistry 285 (18), 13397-13404, 2010
|Functional silencing of HSD17B2 in prostate cancer promotes disease progression|
X Gao, C Dai, S Huang, J Tang, G Chen, J Li, Z Zhu, X Zhu, S Zhou, ...
Clinical Cancer Research 25 (4), 1291-1301, 2019
|Development and validation of a novel LC–MS/MS method for simultaneous determination of abiraterone and its seven steroidal metabolites in human serum: Innovation in separation …|
M Alyamani, Z Li, SK Upadhyay, DJ Anderson, RJ Auchus, N Sharifi
The Journal of steroid biochemistry and molecular biology 172, 231-239, 2017
|The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy|
G Wei, H Sun, K Dong, L Hu, Q Wang, Q Zhuang, Y Zhu, X Zhang, Y Shao, ...
Cell metabolism 33 (10), 2021
|Loss of dihydrotestosterone-inactivation activity promotes prostate cancer castration resistance detectable by functional imaging|
Z Zhu, YM Chung, O Sergeeva, V Kepe, M Berk, J Li, HK Ko, Z Li, M Petro, ...
Journal of Biological Chemistry 293 (46), 17829-17837, 2018
|Androgens in prostate cancer: A tale that never ends|
Z Hou, S Huang, Z Li
Cancer Letters 516, 1-12, 2021
|Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism|
Y Han, Q Zhuang, B Sun, W Lv, S Wang, Q Xiao, B Pang, Y Zhou, F Wang, ...
Nature Communications 12 (1), 449, 2021
|Clinical significance of D4A in prostate cancer therapy with abiraterone|
H Emamekhoo, Z Li, N Sharifi
Cell cycle 14 (20), 3213-3214, 2015
|Inhibiting 3βHSD1 to eliminate the oncogenic effects of progesterone in prostate cancer|
Z Hou, S Huang, Z Mei, L Chen, J Guo, Y Gao, Q Zhuang, X Zhang, Q Tan, ...
Cell Reports Medicine 3 (3), 100561, 2022
|Management of prostate cancer by targeting 3βHSD1 after enzalutamide and abiraterone treatment|
Z Mei, T Yang, Y Liu, Y Gao, Z Hou, Q Zhuang, D He, X Zhang, Q Tan, ...
Cell Reports Medicine 3 (5), 100608, 2022
|Response of prostate cancer to addition of dutasteride after progression on abiraterone|
JP Lian, YY Gao, JJ Tang, X Chen, Y Liu, DL Wu, ZF Li, SS Huang
Asian Journal of Andrology 23 (2), 222, 2021
|Tracing steroidogenesis in prostate biopsy samples to unveil prostate tissue androgen metabolism characteristics and potential clinical application|
Z Hou, T Yang, Z Mei, S Zhang, Y Gao, X Chen, Q Tan, X Zhu, C Xu, ...
The Journal of Steroid Biochemistry and Molecular Biology 210, 105859, 2021
|Celastrol recruits UBE3A to recognize and degrade the DNA binding domain of steroid receptors|
Q Tan, Z Liu, X Gao, Y Wang, X Qiu, J Chen, L Liang, H Guo, S Huang, ...
Oncogene 41 (42), 4754-4767, 2022