Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ... The Lancet 397 (10269), 99-111, 2021 | 5320 | 2021 |
Efficacy of the ChAdOx1 nCoV-19 Covid-19 vaccine against the B. 1.351 variant SA Madhi, V Baillie, CL Cutland, M Voysey, AL Koen, L Fairlie, ... New England Journal of Medicine 384 (20), 1885-1898, 2021 | 1382 | 2021 |
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four … M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ... The Lancet 397 (10277), 881-891, 2021 | 1335 | 2021 |
Long-term outcomes of patients with extensively drug-resistant tuberculosis in South Africa: a cohort study E Pietersen, E Ignatius, EM Streicher, B Mastrapa, X Padanilam, A Pooran, ... The Lancet 383 (9924), 1230-1239, 2014 | 302 | 2014 |
What is the cost of diagnosis and management of drug resistant tuberculosis in South Africa? A Pooran, E Pieterson, M Davids, G Theron, K Dheda PloS one 8 (1), e54587, 2013 | 237 | 2013 |
The intersecting pandemics of tuberculosis and COVID-19: population-level and patient-level impact, clinical presentation, and corrective interventions K Dheda, T Perumal, H Moultrie, R Perumal, A Esmail, AJ Scott, ... The Lancet Respiratory Medicine 10 (6), 603-622, 2022 | 144 | 2022 |
Different screening strategies (single or dual) for the diagnosis of suspected latent tuberculosis: a cost effectiveness analysis A Pooran, H Booth, RF Miller, G Scott, M Badri, JF Huggett, G Rook, ... BMC pulmonary medicine 10, 1-14, 2010 | 143 | 2010 |
Drug-penetration gradients associated with acquired drug resistance in patients with tuberculosis K Dheda, L Lenders, G Magombedze, S Srivastava, P Raj, E Arning, ... American journal of respiratory and critical care medicine 198 (9), 1208-1219, 2018 | 138 | 2018 |
Psychological distress and its relationship with non-adherence to TB treatment: a multicentre study G Theron, J Peter, L Zijenah, D Chanda, C Mangu, P Clowes, A Rachow, ... BMC infectious diseases 15, 1-12, 2015 | 104 | 2015 |
Interpretation of Mycobacterium tuberculosis antigen-specific IFN-γ release assays (T-SPOT. TB) and factors that may modulate test results K Dheda, A Pooran, M Pai, RF Miller, K Lesley, HL Booth, GM Scott, ... Journal of Infection 55 (2), 169-173, 2007 | 104 | 2007 |
Do adjunct tuberculosis tests, when combined with Xpert MTB/RIF, improve accuracy and the cost of diagnosis in a resource-poor setting? G Theron, A Pooran, J Peter, R van Zyl-Smit, HK Mishra, R Meldau, ... European Respiratory Journal 40 (1), 161-168, 2012 | 94 | 2012 |
Comparison of two methods for acquisition of sputum samples for diagnosis of suspected tuberculosis in smear-negative or sputum-scarce people: a randomised controlled trial JG Peter, G Theron, A Pooran, J Thomas, M Pascoe, K Dheda The Lancet Respiratory Medicine 1 (6), 471-478, 2013 | 63 | 2013 |
An all-oral 6-month regimen for multidrug-resistant tuberculosis: a multicenter, randomized controlled clinical trial (the NExT study) A Esmail, S Oelofse, C Lombard, R Perumal, L Mbuthini, ... American Journal of Respiratory and Critical Care Medicine 205 (10), 1214-1227, 2022 | 62 | 2022 |
Burden of tuberculosis in intensive care units in Cape Town, South Africa, and assessment of the accuracy and effect on patient outcomes of the Xpert MTB/RIF test on tracheal … GL Calligaro, G Theron, H Khalfey, J Peter, R Meldau, B Matinyenya, ... The lancet Respiratory medicine 3 (8), 621-630, 2015 | 58 | 2015 |
Point of care Xpert MTB/RIF versus smear microscopy for tuberculosis diagnosis in southern African primary care clinics: a multicentre economic evaluation A Pooran, G Theron, L Zijenah, D Chanda, P Clowes, L Mwenge, ... The Lancet Global Health 7 (6), e798-e807, 2019 | 53 | 2019 |
An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells M Tomasicchio, L Semple, A Esmail, R Meldau, P Randall, A Pooran, ... Cancer Immunology, Immunotherapy 68, 71-83, 2019 | 39 | 2019 |
Same-day tools, including Xpert Ultra and IRISA-TB, for rapid diagnosis of pleural tuberculosis: a prospective observational study R Meldau, P Randall, A Pooran, J Limberis, E Makambwa, M Dhansay, ... Journal of clinical microbiology 57 (9), 10.1128/jcm. 00614-19, 2019 | 37 | 2019 |
IL-4 subverts mycobacterial containment in Mycobacterium tuberculosis-infected human macrophages A Pooran, M Davids, A Nel, A Shoko, J Blackburn, K Dheda European Respiratory Journal 54 (2), 2019 | 36 | 2019 |
A human lung challenge model to evaluate the safety and immunogenicity of PPD and live Bacillus Calmette-Guérin M Davids, A Pooran, C Hermann, L Mottay, F Thompson, J Cardenas, ... American journal of respiratory and critical care medicine 201 (10), 1277-1291, 2020 | 35 | 2020 |
Regulatory T cells subvert mycobacterial containment in patients failing extensively drug-resistant tuberculosis treatment M Davids, AS Pooran, E Pietersen, HC Wainwright, A Binder, R Warren, ... American journal of respiratory and critical care medicine 198 (1), 104-116, 2018 | 32 | 2018 |