Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition‐mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2‐deficient … PM Schoonen, YP Kok, E Wierenga, B Bakker, F Foijer, DCJ Spierings, ... Molecular oncology 13 (11), 2422-2440, 2019 | 80 | 2019 |
Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors YP Kok, S Guerrero Llobet, PM Schoonen, M Everts, A Bhattacharya, ... Oncogenesis 9 (10), 88, 2020 | 56 | 2020 |
TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells SE van Gijn, E Wierenga, N van den Tempel, YP Kok, AM Heijink, ... Oncogene 38 (6), 852-867, 2019 | 54 | 2019 |
Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability ME Geijer, D Zhou, K Selvam, B Steurer, C Mukherjee, B Evers, S Cugusi, ... Nature cell biology 23 (6), 608-619, 2021 | 52 | 2021 |
Shaping the BRCAness mutational landscape by alternative double-strand break repair, replication stress and mitotic aberrancies C Stok, YP Kok, N van den Tempel, MATM van Vugt Nucleic acids research 49 (8), 4239-4257, 2021 | 51 | 2021 |
Modeling of cisplatin-induced signaling dynamics in triple-negative breast cancer cells reveals mediators of sensitivity AM Heijink, M Everts, ME Honeywell, R Richards, YP Kok, EGE de Vries, ... Cell reports 28 (9), 2345-2357. e5, 2019 | 31 | 2019 |
Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51 AM Heijink, C Stok, D Porubsky, EM Manolika, JK de Kanter, YP Kok, ... Nature Communications 13 (1), 6722, 2022 | 23 | 2022 |
The H3. 3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma I Bočkaj, TEI Martini, ES de Camargo Magalhães, PL Bakker, ... PLoS genetics 17 (11), e1009868, 2021 | 18 | 2021 |
FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics C Stok, S Tsaridou, N van den Tempel, M Everts, E Wierenga, FJ Bakker, ... Cell reports 42 (7), 2023 | 7 | 2023 |
Sister chromatid exchanges induced by perturbed replication are formed independently of homologous recombination factors AM Heijink, C Stok, D Porubsky, EM Manolika, YP Kok, M Everts, ... Biorxiv, 2021.09. 17.460736, 2021 | 4 | 2021 |
The FIGNL1-interacting protein C1orf112 is synthetic lethal with PICH and mediates RAD51 retention on chromatin C Stok, N van den Tempel, M Everts, E Wierenga, F Bakker, Y Kok, ... bioRxiv, 2022.10. 07.511242, 2022 | 1 | 2022 |
Causes and consequences of mitotic DNA damage Y Kok | 1 | 2022 |
PPM1D activity promotes the replication stress caused by cyclin E1 overexpression AS Martinikova, M Stoyanov, A Oravetzova, YP Kok, S Yu, J Dobrovolna, ... Molecular oncology 18 (1), 6-20, 2024 | | 2024 |