| Allele-specific ablation rescues electrophysiological abnormalities in a human iPS cell model of long-QT syndrome with a CALM2 mutation Y Yamamoto, T Makiyama, T Harita, K Sasaki, Y Wuriyanghai, M Hayano, ... Human Molecular Genetics 26 (9), 1670-1677, 2017 | 105 | 2017 |
| Patient-specific human induced pluripotent stem cell model assessed with electrical pacing validates S107 as a potential therapeutic agent for catecholaminergic polymorphic … K Sasaki, T Makiyama, Y Yoshida, Y Wuriyanghai, T Kamakura, ... PLoS One 11 (10), e0164795, 2016 | 66 | 2016 |
| Gene-Based Risk Stratification for Cardiac Disorders in LMNA Mutation Carriers S Nishiuchi, T Makiyama, T Aiba, K Nakajima, S Hirose, H Kohjitani, ... Circulation: cardiovascular genetics 10 (6), e001603, 2017 | 64 | 2017 |
| Phenotype-based high-throughput classification of long QT syndrome subtypes using human induced pluripotent stem cells D Yoshinaga, S Baba, T Makiyama, H Shibata, T Hirata, K Akagi, ... Stem cell reports 13 (2), 394-404, 2019 | 36 | 2019 |
| Clinical manifestations and long-term mortality in lamin A/C mutation carriers from a Japanese Multicenter Registry K Nakajima, T Aiba, T Makiyama, S Nishiuchi, S Ohno, K Kato, ... Circulation Journal 82 (11), 2707-2714, 2018 | 32 | 2018 |
| Complex aberrant splicing in the induced pluripotent stem cell–derived cardiomyocytes from a patient with long QT syndrome carrying KCNQ1-A344Aspl mutation Y Wuriyanghai, T Makiyama, K Sasaki, T Kamakura, Y Yamamoto, ... Heart Rhythm 15 (10), 1566-1574, 2018 | 32 | 2018 |
| Development of a patient-derived induced pluripotent stem cell model for the investigation of SCN5A-D1275N-related cardiac sodium channelopathy M Hayano, T Makiyama, T Kamakura, H Watanabe, K Sasaki, ... Circulation Journal 81 (12), 1783-1791, 2017 | 25 | 2017 |
| Cardiac sodium channel mutation associated with epinephrine-induced QT prolongation and sinus node dysfunction J Chen, T Makiyama, Y Wuriyanghai, S Ohno, K Sasaki, M Hayano, ... Heart Rhythm 13 (1), 289-298, 2016 | 24 | 2016 |
| Comparative effects of amlodipine and benazepril on Left Atrial Pressure in Dogs with experimentally-induced Mitral Valve Regurgitation S Suzuki, R Fukushima, T Ishikawa, Y Yamamoto, L Hamabe, S Kim, ... BMC Veterinary Research 8, 1-7, 2012 | 15 | 2012 |
| Propranolol attenuates late sodium current in a long QT syndrome type 3-human induced pluripotent stem cell model S Hirose, T Makiyama, D Melgari, Y Yamamoto, Y Wuriyanghai, F Yokoi, ... Frontiers in Cell and Developmental Biology 8, 761, 2020 | 10 | 2020 |
| Disrupted CaV1. 2 selectivity causes overlapping long QT and Brugada syndrome phenotypes in the CACNA1C-E1115K iPS cell model A Kashiwa, T Makiyama, H Kohjitani, TL Maurissen, T Ishikawa, ... Heart rhythm 20 (1), 89-99, 2023 | 5 | 2023 |
| Novel Calmodulin Variant p. E46K Associated With Severe Catecholaminergic Polymorphic Ventricular Tachycardia Produces Robust Arrhythmogenicity in Human Induced Pluripotent … J Gao, T Makiyama, Y Yamamoto, T Kobayashi, H Aoki, TL Maurissen, ... Circulation: Arrhythmia and Electrophysiology 16 (3), e011387, 2023 | 3 | 2023 |
| Gradient-based parameter optimization method to determine membrane ionic current composition in human induced pluripotent stem cell-derived cardiomyocytes H Kohjitani, S Koda, Y Himeno, T Makiyama, Y Yamamoto, D Yoshinaga, ... Scientific Reports 12 (1), 19110, 2022 | 3 | 2022 |
| Electrophysiological analysis of hiPSC-derived cardiomyocytes using a patch-clamp technique Y Yamamoto, S Hirose, Y Wuriyanghai, D Yoshinaga, T Makiyama Pluripotent Stem-Cell Derived Cardiomyocytes, 121-133, 2021 | 3 | 2021 |
| Calmodulinopathy-Analysis of Human iPS Cell Model of Long-QT Syndrome with a CALM2 Mutation and Therapeutic Approach Using Genome Editing Technology Y YAMAMOTO, T MAKIYAMA JAPANESE JOURNAL OF ELECTROCARDIOLOGY 39 (4), 273-282, 2019 | 3 | 2019 |
| Effects of a Sustained‐Release Form of Isosorbide Dinitrate on Left Atrial Pressure in Dogs with Experimentally Induced Mitral Valve Regurgitation Y Yamamoto, S Suzuki, L Hamabe, D Aytemiz, H Huai‐Che, S Kim, ... Journal of Veterinary Internal Medicine 27 (6), 1421-1426, 2013 | 2 | 2013 |
| Improved Cardiac Performance and Decreased Arrhythmia in Hypertrophic Cardiomyopathy With Non–β-Blocking R-Enantiomer Carvedilol K Seo, Y Yamamoto, A Kirillova, M Kawana, S Yadav, Y Huang, Q Wang, ... Circulation 148 (21), 1691-1704, 2023 | | 2023 |
| Antisense oligonucleotide of calm2 Y Iriyama, Y Kondo, Y Hidaka, R Ishikawa, H Tsukada, T Makiyama, ... US Patent App. 17/908,849, 2023 | | 2023 |
| Antisense oligonucleotide of calm2 Y Iriyama, Y Kondo, Y Hidaka, R ISHIKAWA, H Tsukada, T Makiyama, ... | | 2023 |
| Truncating Variants in MYBPC3 Cause Ubiquitin Proteasome System Dysfunction Related to Hypertrophic Cardiomyopathy in Human Induced Pluripotent Stem … Y Yamamoto, VN Parikh, EA Ashley Circulation 146 (Suppl_1), A14660-A14660, 2022 | | 2022 |
