关注
Prof. Dr. Dirk Isbrandt
Prof. Dr. Dirk Isbrandt
Institute for Molecular and Behavioral Neuroscience, DZNE & University of Cologne
在 dzne.de 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Pacemaker channel dysfunction in a patient with sinus node disease
E Schulze-Bahr, A Neu, P Friederich, UB Kaupp, G Breithardt, O Pongs, ...
The Journal of clinical investigation 111 (10), 1537-1545, 2003
4922003
Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior
HC Peters, H Hu, O Pongs, JF Storm, D Isbrandt
Nature neuroscience 8 (1), 51-60, 2005
4322005
Guanidinoacetate methyltransferase deficiency: the first inborn error of creatine metabolism in man.
S Stöckler, D Isbrandt, F Hanefeld, B Schmidt, K Von Figura
American journal of human genetics 58 (5), 914, 1996
2561996
Conserved Kv4 N-terminal domain critical for effects of Kv channel-interacting protein 2.2 on channel expression and gating
R Bähring, J Dannenberg, HC Peters, T Leicher, O Pongs, D Isbrandt
Journal of Biological Chemistry 276 (26), 23888-23894, 2001
2462001
Adenosine receptor antagonists including caffeine alter fetal brain development in mice
CG Silva, C Métin, W Fazeli, NJ Machado, S Darmopil, PS Launay, ...
Science translational medicine 5 (197), 197ra104-197ra104, 2013
1812013
Severely altered guanidino compound levels, disturbed body weight homeostasis and impaired fertility in a mouse model of guanidinoacetate N-methyltransferase (GAMT) deficiency
A Schmidt, B Marescau, EA Boehm, WKJ Renema, R Peco, A Das, ...
Human molecular genetics 13 (9), 905-921, 2004
1772004
Homoarginine Levels Are Regulated by l-Arginine:Glycine Amidinotransferase and Affect Stroke Outcome: Results From Human and Murine Studies
C Choe, D Atzler, PS Wild, AM Carter, RH Böger, F Ojeda, O Simova, ...
Circulation 128 (13), 1451-1461, 2013
1602013
Activation of GABAA receptors by guanidinoacetate: a novel pathophysiological mechanism
A Neu, H Neuhoff, G Trube, S Fehr, K Ullrich, J Roeper, D Isbrandt
Neurobiology of disease 11 (2), 298-307, 2002
1382002
Reduced inotropic reserve and increased susceptibility to cardiac ischemia/reperfusion injury in phosphocreatine-deficient guanidinoacetate-n-methyltransferase–knockout mice
M ten Hove, CA Lygate, A Fischer, JE Schneider, AE Sang, K Hulbert, ...
Circulation 111 (19), 2477-2485, 2005
1362005
Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions
J Prox, C Bernreuther, H Altmeppen, J Grendel, M Glatzel, R D'Hooge, ...
Journal of Neuroscience 33 (32), 12915-12928, 2013
1352013
Control of heart rate by cAMP sensitivity of HCN channels
J Alig, L Marger, P Mesirca, H Ehmke, ME Mangoni, D Isbrandt
Proceedings of the National Academy of Sciences 106 (29), 12189-12194, 2009
1352009
Treatment during a vulnerable developmental period rescues a genetic epilepsy
SL Marguet, VTQ Le-Schulte, A Merseburg, A Neu, R Eichler, ...
Nature medicine 21 (12), 1436-1444, 2015
1182015
Coexpression of the KCNA3BGene Product with Kv1. 5 Leads to a Novel A-type Potassium Channel
T Leicher, R Bähring, D Isbrandt, O Pongs
Journal of Biological Chemistry 273 (52), 35095-35101, 1998
1031998
N-type inactivation features of Kv4. 2 channel gating
M Gebauer, D Isbrandt, K Sauter, B Callsen, A Nolting, O Pongs, ...
Biophysical journal 86 (1), 210-223, 2004
1012004
Gene structures and expression profiles of three human KCND (Kv4) potassium channels mediating A-type currents ITO and ISA
D Isbrandt, T Leicher, R Waldschütz, X Zhu, U Luhmann, U Michel, ...
Genomics 64 (2), 144-154, 2000
1002000
Disturbed energy metabolism and muscular dystrophy caused by pure creatine deficiency are reversible by creatine intake
CI Nabuurs, CU Choe, A Veltien, HE Kan, LJC van Loon, RJT Rodenburg, ...
The Journal of physiology 591 (2), 571-592, 2013
962013
l-arginine:glycine amidinotransferase deficiency protects from metabolic syndrome
C Choe, C Nabuurs, MC Stockebrand, A Neu, P Nunes, F Morellini, ...
Human molecular genetics 22 (1), 110-123, 2013
962013
Functional roles of Cav1.3, Cav3.1 and HCN channels in automaticity of mouse atrioventricular cells: Insights into the atrioventricular pacemaker mechanism
L Marger, P Mesirca, J Alig, A Torrente, S Dübel, B Engeland, S Kanani, ...
Channels 5 (3), 251-261, 2011
932011
Cardiac arrhythmia induced by genetic silencing of ‘funny’ (f) channels is rescued by GIRK4 inactivation
P Mesirca, J Alig, AG Torrente, JC Müller, L Marger, A Rollin, C Marquilly, ...
Nature communications 5 (1), 4664, 2014
882014
Identification and functional characterization of a novel KCNE2 (MiRP1) mutation that alters HERG channel kinetics
D Isbrandt, P Friederich, A Solth, W Haverkamp, A Ebneth, M Borggrefe, ...
Journal of molecular medicine 80, 524-532, 2002
852002
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