| Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 441 | 2021 |
| X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science immunology 6 (62), eabl4348, 2021 | 334 | 2021 |
| The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 128 | 2022 |
| Autoantibodies against type I interferons are associated with multi-organ failure in COVID-19 patients R Koning, P Bastard, JL Casanova, MC Brouwer, D van de Beek Intensive care medicine 47, 704-706, 2021 | 110 | 2021 |
| Clinical features and prognostic factors in Covid-19: a prospective cohort study S de Bruin, LD Bos, MA van Roon, AM Tuip-de Boer, AR Schuurman, ... EBioMedicine 67, 2021 | 92 | 2021 |
| Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo … APJ Vlaar, M Witzenrath, P van Paassen, LMA Heunks, B Mourvillier, ... The Lancet Respiratory Medicine 10 (12), 1137-1146, 2022 | 66 | 2022 |
| The diagnostic accuracy of lung auscultation in adult patients with acute pulmonary pathologies: a meta-analysis L Arts, EHT Lim, PM van de Ven, L Heunks, PR Tuinman Scientific reports 10 (1), 7347, 2020 | 66 | 2020 |
| EXpert consensus On Diaphragm UltraSonography in the critically ill (EXODUS): a Delphi consensus statement on the measurement of diaphragm ultrasound-derived parameters in a … ME Haaksma, JM Smit, A Boussuges, A Demoule, M Dres, G Ferrari, ... Critical Care 26 (1), 99, 2022 | 54 | 2022 |
| Indoleamine 2, 3‐dioxygenase (IDO)‐1 and IDO‐2 activity and severe course of COVID‐19 L Guo, B Schurink, E Roos, EJ Nossent, JW Duitman, APJ Vlaar, ... The Journal of pathology 256 (3), 256-261, 2022 | 32 | 2022 |
| Ultrasound to detect central venous catheter placement associated complications: a multicenter diagnostic accuracy study JM Smit, ME Haaksma, EHT Lim, TS Steenvoorden, MJ Blans, FH Bosch, ... Anesthesiology 132 (4), 781-794, 2020 | 29 | 2020 |
| Complement activation in COVID-19 and targeted therapeutic options: a scoping review EHT Lim, RBE van Amstel, VV de Boer, LA van Vught, S de Bruin, ... Blood Reviews 57, 100995, 2023 | 28 | 2023 |
| The anti‐C5a antibody vilobelimab efficiently inhibits C5a in patients with severe COVID‐19 APJ Vlaar, EHT Lim, S de Bruin, S Rückinger, K Pilz, MC Brouwer, ... Clinical and Translational Science 15 (4), 854-858, 2022 | 27 | 2022 |
| Holistic ultrasound to predict extubation failure in clinical practice ME Haaksma, JM Smit, MLA Heldeweg, JS Nooitgedacht, ... Respiratory care 66 (6), 994-1003, 2021 | 17 | 2021 |
| Complement inhibition in severe COVID-19–Blocking C5a seems to be key EHT Lim, APJ Vlaar, S de-Bruin, MC Brouwer, D van-de-Beek EClinicalMedicine 35, 2021 | 11 | 2021 |
| Neurofilament light increases over time in severe COVID-19 and is associated with delirium PJ Smeele, L Vermunt, S Blok, JW Duitman, EJ Nossent, MA van Agtmael, ... Brain Communications 4 (4), fcac195, 2022 | 9 | 2022 |
| Association between dexamethasone treatment and the host response in COVID-19 patients admitted to the general ward J de Brabander, EHA Michels, CCA van Linge, O Chouchane, RA Douma, ... Respiratory research 23 (1), 145, 2022 | 9 | 2022 |
| Age-related changes in plasma biomarkers and their association with mortality in COVID-19 EHA Michels, B Appelman, J de Brabander, RBE van Amstel, ... European Respiratory Journal 62 (1), 2023 | 8 | 2023 |
| Anti-C5a antibody vilobelimab treatment and the effect on biomarkers of inflammation and coagulation in patients with severe COVID-19: a substudy of the phase 2 PANAMO trial EHT Lim, APJ Vlaar, LDJ Bos, LA van Vught, AMT Boer, RWG Dujardin, ... Respiratory research 23 (1), 375, 2022 | 7 | 2022 |
| Inflammatory biomarkers at hospital discharge are associated with readmission and death in patients hospitalized for COVID-19 MA Slim, B Appelman, MCA Müller, MC Brouwer, APJ Vlaar, ... European Journal of Clinical Microbiology & Infectious Diseases 40, 2677-2683, 2021 | 4 | 2021 |
| Pharmacokinetic analysis of vilobelimab, anaphylatoxin C5a and antidrug antibodies in PANAMO: a phase 3 study in critically ill, invasively mechanically ventilated COVID-19 … EHT Lim, APJ Vlaar, S de Bruin, S Rückinger, C Thielert, M Habel, R Guo, ... Intensive Care Medicine Experimental 11 (1), 37, 2023 | 3 | 2023 |
