Tamoxifen inhibits TGF‐β‐mediated activation of myofibroblasts by blocking non‐Smad signaling through ERK1/2 JM Carthy, A Sundqvist, A Heldin, H Van Dam, D Kletsas, CH Heldin, ... Journal of cellular physiology 230 (12), 3084-3092, 2015 | 76 | 2015 |
Synergistic rescue of nonsense mutant tumor suppressor p53 by combination treatment with aminoglycosides and Mdm2 inhibitors M Zhang, A Heldin, M Palomar-Siles, S Öhlin, VJN Bykov, KG Wiman Frontiers in oncology 7, 323, 2018 | 35 | 2018 |
Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation JM Carthy, M Stöter, C Bellomo, M Vanlandewijck, A Heldin, A Morén, ... Scientific Reports 6 (1), 29868, 2016 | 15 | 2016 |
Translational readthrough of nonsense mutant TP53 by mRNA incorporation of 5-Fluorouridine M Palomar-Siles, A Heldin, M Zhang, C Strandgren, V Yurevych, ... Cell Death & Disease 13 (11), 997, 2022 | 12 | 2022 |
Pharmacological reactivation of p53 in the era of precision anticancer medicine A Tuval, C Strandgren, A Heldin, M Palomar-Siles, KG Wiman Nature Reviews Clinical Oncology 21 (2), 106-120, 2024 | 7 | 2024 |
Novel compounds that synergize with aminoglycoside G418 or eRF3 degraders for translational readthrough of nonsense mutant TP53 and PTEN A Heldin, M Cancer, M Palomar-Siles, S Öhlin, M Zhang, A Sun-Zhang, ... RNA biology 20 (1), 368-383, 2023 | | 2023 |
Pharmacological Targeting of Nonsense Mutant TP53 and PTEN in Cancer A Heldin PQDT-Global, 2023 | | 2023 |
Screening for chemical regulators of epithelial plasticity points to a nuclear receptor pathway controlling myofibroblast differentiation J Carthy, M Stöter, C Bellomo, M Vanlandewijck, A Heldin, A Morén, ... | | |
Original Research Article Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling through ERK1/2 J CARTHY, A SUNDQVIST, A HELDIN, H VAN DAM, D KLETSAS, ... | | |