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Angelos Heldin
Angelos Heldin
PhD student, Karolionska institutet
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Tamoxifen inhibits TGF‐β‐mediated activation of myofibroblasts by blocking non‐Smad signaling through ERK1/2
JM Carthy, A Sundqvist, A Heldin, H Van Dam, D Kletsas, CH Heldin, ...
Journal of cellular physiology 230 (12), 3084-3092, 2015
762015
Synergistic rescue of nonsense mutant tumor suppressor p53 by combination treatment with aminoglycosides and Mdm2 inhibitors
M Zhang, A Heldin, M Palomar-Siles, S Öhlin, VJN Bykov, KG Wiman
Frontiers in oncology 7, 323, 2018
352018
Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation
JM Carthy, M Stöter, C Bellomo, M Vanlandewijck, A Heldin, A Morén, ...
Scientific Reports 6 (1), 29868, 2016
152016
Translational readthrough of nonsense mutant TP53 by mRNA incorporation of 5-Fluorouridine
M Palomar-Siles, A Heldin, M Zhang, C Strandgren, V Yurevych, ...
Cell Death & Disease 13 (11), 997, 2022
122022
Pharmacological reactivation of p53 in the era of precision anticancer medicine
A Tuval, C Strandgren, A Heldin, M Palomar-Siles, KG Wiman
Nature Reviews Clinical Oncology 21 (2), 106-120, 2024
72024
Novel compounds that synergize with aminoglycoside G418 or eRF3 degraders for translational readthrough of nonsense mutant TP53 and PTEN
A Heldin, M Cancer, M Palomar-Siles, S Öhlin, M Zhang, A Sun-Zhang, ...
RNA biology 20 (1), 368-383, 2023
2023
Pharmacological Targeting of Nonsense Mutant TP53 and PTEN in Cancer
A Heldin
PQDT-Global, 2023
2023
Screening for chemical regulators of epithelial plasticity points to a nuclear receptor pathway controlling myofibroblast differentiation
J Carthy, M Stöter, C Bellomo, M Vanlandewijck, A Heldin, A Morén, ...
Original Research Article Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling through ERK1/2
J CARTHY, A SUNDQVIST, A HELDIN, H VAN DAM, D KLETSAS, ...
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