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Ivan Tochitsky
Ivan Tochitsky
Regeneron Pharmaceuticals, Inc.
Verified email at childrens.harvard.edu
Title
Cited by
Cited by
Year
Transcriptional reprogramming of distinct peripheral sensory neuron subtypes after axonal injury
W Renthal, I Tochitsky, L Yang, YC Cheng, E Li, R Kawaguchi, ...
Neuron 108 (1), 128-144. e9, 2020
2812020
Photochemical restoration of visual responses in blind mice
A Polosukhina, J Litt, I Tochitsky, J Nemargut, Y Sychev, ...
Neuron 75 (2), 271-282, 2012
2682012
LiGluR restores visual responses in rodent models of inherited blindness
N Caporale, KD Kolstad, T Lee, I Tochitsky, D Dalkara, D Trauner, ...
Molecular therapy 19 (7), 1212-1219, 2011
2012011
Restoring visual function to blind mice with a photoswitch that exploits electrophysiological remodeling of retinal ganglion cells
I Tochitsky, A Polosukhina, VE Degtyar, N Gallerani, CM Smith, ...
Neuron 81 (4), 800-813, 2014
2002014
Optochemical control of genetically engineered neuronal nicotinic acetylcholine receptors
I Tochitsky, MR Banghart, A Mourot, JZ Yao, B Gaub, RH Kramer, ...
Nature chemistry 4 (2), 105-111, 2012
1832012
Restoring vision to the blind with chemical photoswitches
I Tochitsky, MA Kienzler, E Isacoff, RH Kramer
Chemical reviews 118 (21), 10748-10773, 2018
1472018
Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin
M Sundberg, I Tochitsky, DE Buchholz, K Winden, V Kujala, K Kapur, ...
Molecular psychiatry 23 (11), 2167-2183, 2018
922018
How azobenzene photoswitches restore visual responses to the blind retina
I Tochitsky, Z Helft, V Meseguer, RB Fletcher, KA Vessey, M Telias, ...
Neuron 92 (1), 100-113, 2016
652016
Light at the end of the channel: optical manipulation of intrinsic neuronal excitability with chemical photoswitches
A Mourot, I Tochitsky, RH Kramer
Frontiers in molecular neuroscience 6, 5, 2013
582013
Photopharmacological control of bipolar cells restores visual function in blind mice
L Laprell, I Tochitsky, K Kaur, MB Manookin, M Stein, DM Barber, C Schön, ...
The Journal of clinical investigation 127 (7), 2598-2611, 2017
492017
Restoring visual function to the blind retina with a potent, safe and long-lasting photoswitch
I Tochitsky, J Trautman, N Gallerani, JG Malis, RH Kramer
Scientific reports 7 (1), 45487, 2017
472017
Optopharmacological tools for restoring visual function in degenerative retinal diseases
I Tochitsky, RH Kramer
Current opinion in neurobiology 34, 74-78, 2015
302015
Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons
YC Cheng, A Snavely, LB Barrett, X Zhang, C Herman, DJ Frost, P Riva, ...
Cell reports 36 (10), 2021
212021
Inhibition of inflammatory pain and cough by a novel charged sodium channel blocker
I Tochitsky, S Jo, N Andrews, M Kotoda, B Doyle, J Shim, S Talbot, ...
British journal of pharmacology 178 (19), 3905-3923, 2021
202021
Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia
SA Bhuiyan, M Xu, L Yang, E Semizoglou, P Bhatia, KI Pantaleo, ...
bioRxiv, 2023
82023
Isolation of nuclei from mouse dorsal root ganglia for single-nucleus genomics
L Yang, I Tochitsky, CJ Woolf, W Renthal
Bio-protocol 11 (15), e4102-e4102, 2021
52021
Photopharmacology: controlling native voltage-gated ion channels with light
A Mourot, T Fehrentz, M Kienzler, I Tochitsky, MR Banghart, D Trauner, ...
Biophysical Journal 98 (3), 212a, 2010
32010
Photochemical restoration of light sensitivity in the degenerated canine retina
S Nikonov, N Dolgova, R Sudharsan, I Tochitsky, S Iwabe, JM Guzman, ...
Pharmaceutics 14 (12), 2711, 2022
12022
Charged ion channel blockers and methods for use thereof
BP Bean, CJ Woolf, J Lee, JO Sooyeon, I Tochitsky
US Patent App. 16/733,762, 2020
12020
Azobenzene-based DENAQ photoswitch confers light sensitivity to degenerated but not to healthy canine retina
S Nikonov, N Dolgova, I Tochitsky, RN Van Gelder, R Kramer, GD Aguirre, ...
Investigative Ophthalmology & Visual Science 57 (12), 602-602, 2016
12016
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