AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965 TA Dite, CG Langendorf, A Hoque, S Galic, RJ Rebello, AJ Ovens, ... Journal of Biological Chemistry 293 (23), 8874-8885, 2018 | 123 | 2018 |
Structural determinants for small-molecule activation of skeletal muscle AMPK α2β2γ1 by the glucose importagog SC4 KRW Ngoei, CG Langendorf, NXY Ling, A Hoque, S Varghese, ... Cell chemical biology 25 (6), 728-737. e9, 2018 | 49 | 2018 |
Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965 D Ahwazi, K Neopane, GR Markby, F Kopietz, AJ Ovens, M Dall, ... Biochemical Journal 478 (15), 2977-2997, 2021 | 28 | 2021 |
Import of extracellular ATP in yeast and man modulates AMPK and TORC1 signalling GM Forte, E Davie, S Lie, M Franz-Wachtel, AJ Ovens, T Wang, JS Oakhill, ... Journal of cell science 132 (7), jcs223925, 2019 | 25 | 2019 |
Post-translational modifications of the energy guardian AMP-activated protein kinase AJ Ovens, JW Scott, CG Langendorf, BE Kemp, JS Oakhill, WJ Smiles International journal of molecular sciences 22 (3), 1229, 2021 | 18 | 2021 |
Compound-and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle P Rhein, EM Desjardins, P Rong, D Ahwazi, N Bonhoure, J Stolte, ... Molecular Metabolism 51, 101228, 2021 | 14 | 2021 |
Genetic impairment of succinate metabolism disrupts bioenergetic sensing in adrenal neuroendocrine cancer P Gupta, K Strange, R Telange, A Guo, H Hatch, A Sobh, J Elie, AM Carter, ... Cell reports 40 (7), 2022 | 10 | 2022 |
Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator AJ Ovens, YS Gee, NXY Ling, D Yu, JP Hardee, JD Chung, KRW Ngoei, ... Biochemical Journal 479 (11), 1181-1204, 2022 | 7 | 2022 |
Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis K Neopane, N Kozlov, F Negoita, L Murray-Segal, R Brink, A Hoque, ... Cell Reports 41 (12), 2022 | 5 | 2022 |
Moving towards isoform-specific AMPK activation AJ Ovens Australian Catholic University, 2022 | | 2022 |
Novel torin1-sensitive phosphorylation sites on the metabolic regulator AMPK revealed by label-free mass spectrometry WJ Smiles, AJ Ovens, D Yu, NXY Ling, KR Morrison, A Hoque, JW Scott, ... bioRxiv, 2021.10. 20.462995, 2021 | | 2021 |