| Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease BJ Ryan, S Hoek, EA Fon, R Wade-Martins Trends in biochemical sciences 40 (4), 200-210, 2015 | 618 | 2015 |
| ER stress and autophagic perturbations lead to elevated extracellular α-synuclein in GBA-N370S Parkinson's iPSC-derived dopamine neurons HJR Fernandes, EM Hartfield, HC Christian, E Emmanoulidou, Y Zheng, ... Stem cell reports 6 (3), 342-356, 2016 | 380 | 2016 |
| Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model S Janezic, S Threlfell, PD Dodson, MJ Dowie, TN Taylor, D Potgieter, ... Proceedings of the National Academy of Sciences 110 (42), E4016-E4025, 2013 | 375 | 2013 |
| Mitochondrial dysfunction and mitophagy in Parkinson’s disease: from mechanism to therapy AB Malpartida, M Williamson, DP Narendra, R Wade-Martins, BJ Ryan Trends in biochemical sciences 46 (4), 329-343, 2021 | 369 | 2021 |
| Single-cell sequencing of iPSC-dopamine neurons reconstructs disease progression and identifies HDAC4 as a regulator of Parkinson cell phenotypes C Lang*, KR Campbell*, BJ Ryan, P Carling, M Attar, J Vowles, ... Cell stem cell 24 (1), 93-106. e6, 2019 | 169 | 2019 |
| Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson’s iPSC-derived dopamine neurons F Zambon, M Cherubini, HJR Fernandes, C Lang, BJ Ryan, V Volpato, ... Human Molecular Genetics 28 (12), 2001-2013, 2019 | 157 | 2019 |
| Autoantibodies to posttranslational modifications in rheumatoid arthritis AN Burska, L Hunt, M Boissinot, R Strollo, BJ Ryan, E Vital, A Nissim, ... Mediators of Inflammation 2014 (1), 492873, 2014 | 126 | 2014 |
| Measurement and meaning of markers of reactive species of oxygen, nitrogen and sulfur in healthy human subjects and patients with inflammatory joint disease PG Winyard, B Ryan, P Eggleton, A Nissim, E Taylor, ML Lo Faro, ... Biochemical society transactions 39 (5), 1226-1232, 2011 | 119* | 2011 |
| Oxidative post-translational modifications and their involvement in the pathogenesis of autoimmune diseases BJ Ryan, A Nissim, PG Winyard Redox biology 2, 715-724, 2014 | 116 | 2014 |
| Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells AM Smith, C Depp, BJ Ryan, GI Johnston, J Alegre‐Abarrategui, S Evetts, ... Movement Disorders 33 (10), 1580-1590, 2018 | 100 | 2018 |
| Extracellular calreticulin is present in the joints of patients with rheumatoid arthritis and inhibits FasL (CD95L)–mediated apoptosis of T cells JM Tarr, PG Winyard, B Ryan, LW Harries, R Haigh, N Viner, P Eggleton Arthritis & Rheumatism 62 (10), 2919-2929, 2010 | 77 | 2010 |
| PARK2 Mutation Causes Metabolic Disturbances and Impaired Survival of Human iPSC-Derived Neurons H Bogetofte, P Jensen, M Ryding, SI Schmidt, J Okarmus, L Ritter, ... Frontiers in cellular neuroscience 13, 297, 2019 | 73 | 2019 |
| A novel role for endothelial tetrahydrobiopterin in mitochondrial redox balance J Bailey, A Shaw, R Fischer, BJ Ryan, BM Kessler, J McCullagh, ... Free Radical Biology and Medicine 104, 214-225, 2017 | 63 | 2017 |
| Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse TN Taylor, D Potgieter, S Anwar, SL Senior, S Janezic, S Threlfell, B Ryan, ... Neurobiology of disease 62, 193-207, 2014 | 60 | 2014 |
| Oxidative and other posttranslational modifications in extracellular vesicle biology K Szabó-Taylor, B Ryan, X Osteikoetxea, TG Szabó, B Sódar, M Holub, ... Seminars in cell & developmental biology 40, 8-16, 2015 | 58 | 2015 |
| C-type natriuretic peptide and natriuretic peptide receptor B signalling inhibits cardiac sympathetic neurotransmission and autonomic function J Buttgereit, J Shanks, D Li, G Hao, A Athwal, TH Langenickel, H Wright, ... Cardiovascular research 112 (3), 637-644, 2016 | 44 | 2016 |
| Lysosomal perturbations in human dopaminergic neurons derived from induced pluripotent stem cells with PARK2 mutation J Okarmus, H Bogetofte, SI Schmidt, M Ryding, S García-López, BJ Ryan, ... Scientific Reports 10 (1), 10278, 2020 | 39 | 2020 |
| Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation H Bogetofte, P Jensen, J Okarmus, SI Schmidt, M Agger, M Ryding, ... Neurobiology of Disease 132, 104581, 2019 | 38 | 2019 |
| A requirement for Gch1 and tetrahydrobiopterin in embryonic development G Douglas, AB Hale, MJ Crabtree, BJ Ryan, A Hansler, K Watschinger, ... Developmental biology 399 (1), 129-138, 2015 | 37 | 2015 |
| α-Synuclein and mitochondrial bioenergetics regulate tetrahydrobiopterin levels in a human dopaminergic model of Parkinson disease BJ Ryan, LL Lourenço-Venda, MJ Crabtree, AB Hale, KM Channon, ... Free Radical Biology and Medicine 67, 58-68, 2014 | 37 | 2014 |
Paul WinyardUniversity of Exeter and Watercress Research LimitedVerified email at exeter.ac.uk
