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Hao Zhang
Hao Zhang
Weill Cornell Medicine
Verified email at med.cornell.edu
Title
Cited by
Cited by
Year
Activity of epigenetic inhibitors against Plasmodium falciparum asexual and sexual blood stages
LN Vanheer, H Zhang, G Lin, BFC Kafsack
Antimicrobial agents and chemotherapy 64 (7), 10.1128/aac. 02523-19, 2020
392020
Improvement of Asparagine Ethylenediamines as Anti-malarial Plasmodium-Selective Proteasome Inhibitors
W Zhan, J Visone, T Ouellette, JC Harris, R Wang, H Zhang, PK Singh, ...
Journal of medicinal chemistry 62 (13), 6137-6145, 2019
342019
Development of a highly selective Plasmodium falciparum proteasome inhibitor with anti‐malaria activity in humanized mice
G Lin, W Zhan, H Zhang, J Ginn, A Leung, YJ Liu, M Michino, A Toita, ...
Angewandte Chemie International Edition, 2021
272021
Total synthesis of (−)-gardmultimine A
P Chen, H Yang, H Zhang, W Chen, Z Zhang, J Zhang, H Li, X Wang, ...
Organic letters 22 (5), 2022-2025, 2020
232020
Microbial proteasomes as drug targets
H Zhang, G Lin
PLoS Pathogens 17 (12), e1010058, 2021
212021
Biomimetic Total Syntheses of (+)-Dihydrolyfoline and (−)-5-epi-Dihydrolyfoline
R Mei, D Xu, H Hu, D Song, H Zhang, D Ma, X Xie, X She
Organic letters 17 (9), 2230-2233, 2015
192015
Palladium-promoted neutral 1, 4-Brook rearrangement/intramolecular allylic cyclization cascade reaction: A strategy for the construction of vinyl cyclobutanols
H Zhang, S Ma, Z Yuan, P Chen, X Xie, X Wang, X She
Organic letters 19 (13), 3478-3481, 2017
162017
Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome
I Deni, BH Stokes, KE Ward, KJ Fairhurst, CFA Pasaje, T Yeo, S Akbar, ...
Cell chemical biology 30 (5), 470-485. e6, 2023
142023
Total synthesis of conosilane A via a site-selective C–H functionalization strategy
Z Yuan, X Hu, H Zhang, L Liu, P Chen, M He, X Xie, X Wang, X She
Chemical Communications 54 (8), 912-915, 2018
132018
Design, synthesis, and optimization of macrocyclic peptides as species-selective antimalaria proteasome inhibitors
H Zhang, J Ginn, W Zhan, YJ Liu, A Leung, A Toita, R Okamoto, TT Wong, ...
Journal of medicinal chemistry 65 (13), 9350-9375, 2022
112022
Bioinspired total synthesis of (−)-gymnothelignan L
P Chen, L Huo, H Li, L Liu, Z Yuan, H Zhang, S Feng, X Xie, X Wang, ...
Organic Chemistry Frontiers 5 (7), 1124-1128, 2018
112018
Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome
H Zhang, HC Hsu, SC Kahne, R Hara, W Zhan, X Jiang, K Burns-Huang, ...
Journal of medicinal chemistry 64 (9), 6262-6272, 2021
92021
Rapid Construction of The 6/6/5 Tricyclic Framework via a tandem radical cyclization reaction and its application to the synthesis of 5-epi-7-deoxy-isoabietenin A
H Zhang, S Ma, Z Xing, L Liu, B Fang, X Xie, X She
Organic Chemistry Frontiers 4 (11), 2211-2215, 2017
92017
Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance
W Zhan, D Li, SB Subramanyaswamy, YJ Liu, C Yang, H Zhang, JC Harris, ...
Cell chemical biology 30 (5), 457-469. e11, 2023
72023
Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors
HC Hsu, D Li, W Zhan, J Ye, YJ Liu, A Leung, J Qin, B Crespo, FJ Gamo, ...
Nature Communications 14 (1), 8302, 2023
52023
Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum
JM Bennett, KE Ward, RK Muir, S Kabeche, E Yoo, T Yeo, G Lam, ...
ACS Infectious Diseases 9 (10), 2036-2047, 2023
52023
Structure–Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II
H Zhang, J Ginn, W Zhan, A Leung, YJ Liu, A Toita, R Okamoto, TT Wong, ...
Journal of medicinal chemistry 66 (2), 1484-1508, 2023
52023
Concise Total Synthesis of Isospongian Diterpenoid (±)‐Polyrhaphin D
Z Wang, Z Xing, L Liu, H Zhang, Z Zhong, DX Xie, X She
ChemistrySelect 1 (10), 2225-2227, 2016
52016
Discovery of highly selective inhibitors of the human constitutive proteasome β5c chymotryptic subunit
W Zhan, D Li, P Saha, R Wang, H Zhang, AK Ajay, C Deban, G Sukenick, ...
Journal of medicinal chemistry 66 (2), 1172-1185, 2023
32023
High-Throughput/High Content Imaging Screen Identifies Novel Small Molecule Inhibitors and Immunoproteasomes as Therapeutic Targets for Chordoma
AK Ajay, P Chu, P Patel, C Deban, C Roychowdhury, R Heda, A Halawi, ...
Pharmaceutics 15 (4), 1274, 2023
12023
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