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Thomas Binz
Thomas Binz
Verified email at mh-hannover.de
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Year
Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25
J Blasi, ER Chapman, E Link, T Binz, S Yamasaki, PD Camilli, TC Südhof, ...
Nature 365 (6442), 160-163, 1993
15391993
Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly.
T Hayashi, H McMahon, S Yamasaki, T Binz, Y Hata, TC Südhof, ...
The EMBO journal 13 (21), 5051-5061, 1994
9741994
Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC‐1/syntaxin.
J Blasi, ER Chapman, S Yamasaki, T Binz, H Niemann, R Jahn
The EMBO journal 12 (12), 4821-4828, 1993
7011993
Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein
HT McMahon, YA Ushkaryov, L Edelmann, E Link, T Binz, H Niemann, ...
Nature 364 (6435), 346-349, 1993
6081993
Proteolysis of SNAP-25 by types E and A botulinal neurotoxins.
T Binz, J Blasi, S Yamasaki, A Baumeister, E Link, TC Südhof, R Jahn, ...
Journal of biological chemistry 269 (3), 1617-1620, 1994
5271994
Tetanus toxin action: inhibition of neurotransmitter release linked to synaptobrevin proteolysis
E Link, L Edelmann, JH Chou, T Binz, S Yamasaki, U Eisel, M Baumert, ...
Biochemical and biophysical research communications 189 (2), 1017-1023, 1992
4061992
The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves
S Mahrhold, A Rummel, H Bigalke, B Davletov, T Binz
FEBS letters 580 (8), 2011-2014, 2006
3902006
The complete sequence of botulinum neurotoxin type A and comparison with other clostridial neurotoxins.
T Binz, H Kurazono, M Wille, J Frevert, K Wernars, H Niemann
Journal of Biological Chemistry 265 (16), 9153-9158, 1990
3891990
Multiple kinetic components of exocytosis distinguished by neurotoxin sensitivity
T Xu, T Binz, H Niemann, E Neher
Nature neuroscience 1 (3), 192-200, 1998
3881998
Cleavage of members of the synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin.
S Yamasaki, A Baumeister, T Binz, J Blasi, E Link, F Cornille, B Roques, ...
Journal of biological chemistry 269 (17), 12764-12772, 1994
3261994
Disassembly of the reconstituted synaptic vesicle membrane fusion complex in vitro.
T Hayashi, S Yamasaki, S Nauenburg, T Binz, H Niemann
The EMBO journal 14 (10), 2317-2325, 1995
3251995
Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G
A Rummel, T Karnath, T Henke, H Bigalke, T Binz
Journal of Biological Chemistry 279 (29), 30865-30870, 2004
3072004
The HCC‐domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction
A Rummel, S Mahrhold, H Bigalke, T Binz
Molecular microbiology 51 (3), 631-643, 2004
2902004
Tetanus toxin-mediated cleavage of cellubrevin impairs exocytosis of transferrin receptor-containing vesicles in CHO cells.
T Galli, T Chilcote, O Mundigl, T Binz, H Niemann, P De Camilli
The Journal of cell biology 125 (5), 1015-1024, 1994
2881994
Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity
R Jin, A Rummel, T Binz, AT Brunger
Nature 444 (7122), 1092-1095, 2006
2732006
Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25
G Nagy, K Reim, U Matti, N Brose, T Binz, J Rettig, E Neher, JB Sørensen
Neuron 41 (3), 417-429, 2004
2692004
Proteolysis of SNAP‐25 isoforms by botulinum neurotoxin types A, C, and E: domains and amino acid residues controlling the formation of enzyme‐substrate complexes and cleavage
VV Vaidyanathan, K Yoshino, M Jahnz, C Dörries, S Bade, S Nauenburg, ...
Journal of neurochemistry 72 (1), 327-337, 1999
2641999
Cell entry strategy of clostridial neurotoxins
T Binz, A Rummel
Journal of neurochemistry 109 (6), 1584-1595, 2009
2222009
Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept
A Rummel, T Eichner, T Weil, T Karnath, A Gutcaits, S Mahrhold, ...
Proceedings of the National Academy of Sciences 104 (1), 359-364, 2007
2082007
Protein kinase C-dependent phosphorylation of synaptosome-associated protein of 25 kDa at Ser187 potentiates vesicle recruitment
G Nagy, U Matti, RB Nehring, T Binz, J Rettig, E Neher, JB Sørensen
Journal of Neuroscience 22 (21), 9278-9286, 2002
2022002
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