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Arjun Baghela
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Predicting sepsis severity at first clinical presentation: The role of endotypes and mechanistic signatures
A Baghela, OM Pena, AH Lee, B Baquir, R Falsafi, A An, SW Farmer, ...
EBioMedicine 75, 2022
792022
Systems biology approaches to understanding the human immune system
BK Dhillon, M Smith, A Baghela, AHY Lee, REW Hancock
Frontiers in Immunology 11, 542199, 2020
362020
An overview of biological and computational methods for designing mechanism-informed anti-biofilm agents
AY An, KYG Choi, AS Baghela, REW Hancock
Frontiers in Microbiology 12, 640787, 2021
342021
The stringent stress response controls proteases and global regulators under optimal growth conditions in Pseudomonas aeruginosa
D Pletzer, TM Blimkie, H Wolfmeier, Y Li, A Baghela, AHY Lee, R Falsafi, ...
MSystems 5 (4), 10.1128/msystems. 00495-20, 2020
252020
Predicting severity in COVID-19 disease using sepsis blood gene expression signatures
A Baghela, A An, P Zhang, E Acton, J Gauthier, E Brunet-Ratnasingham, ...
Scientific Reports 13 (1), 1247, 2023
242023
NtrBC regulates invasiveness and virulence of Pseudomonas aeruginosa during high-density infection
MA Alford, A Baghela, ATY Yeung, D Pletzer, REW Hancock
Frontiers in microbiology 11, 533374, 2020
222020
Gene expression profiling: Identification of novel pathways and potential biomarkers in severe acute pancreatitis
M Nesvaderani, BK Dhillon, T Chew, B Tang, A Baghela, REW Hancock, ...
Journal of the American College of Surgeons 234 (5), 803-815, 2022
192022
Predicting sepsis severity at first clinical presentation: The role of endotypes and mechanistic signatures. EBioMedicine. 2022; 75: 103776
A Baghela, OM Pena, AH Lee, B Baquir, R Falsafi, A An, SW Farmer, ...
72021
Severe COVID-19 and non-COVID-19 severe sepsis converge transcriptionally after a week in the intensive care unit, indicating common disease mechanisms
AY An, A Baghela, P Zhang, R Falsafi, AH Lee, U Trahtemberg, AJ Baker, ...
Frontiers in Immunology 14, 1167917, 2023
52023
Facilitating systems-level analyses of all-cause and Covid-mediated sepsis through SeptiSearch, a manually-curated compendium of dysregulated gene sets
AS Baghela, J Tam, TM Blimkie, BK Dhillon, REW Hancock
Frontiers in Immunology 14, 1135859, 2023
32023
The stringent stress response controls proteases and global regulators under optimal growth conditions in Pseudomonas aeruginosa. mSystems 5: e00495-20
D Pletzer, TM Blimkie, H Wolfmeier, Y Li, A Baghela, AHY Lee, R Falsafi, ...
32020
Gene Expression Profiling in Pediatric Appendicitis
BK Dhillon, S Kortbeek, A Baghela, M Brindle, DA Martin, CN Jenne, ...
JAMA pediatrics, 2024
22024
Hackathon-driven tutorial development
BM Grande, A Baghela, A Cavalla, F Privé, P Zhang, Y Zhen
F1000Research 7, 1974, 2018
22018
Persistence is key: unresolved immune dysfunction is lethal in both COVID-19 and non-COVID-19 sepsis
AY An, A Baghela, P Zhang, R Falsafi, AH Lee, U Trahtemberg, AJ Baker, ...
Frontiers in Immunology 14, 1254873, 2023
12023
Post-COVID symptoms are associated with endotypes reflecting poor inflammatory and hemostatic modulation
AY An, A Baghela, PGY Zhang, TM Blimkie, J Gauthier, DE Kaufmann, ...
Frontiers in Immunology 14, 1243689, 2023
12023
Dynamic gene expression analysis reveals distinct severity phases of immune and cellular dysregulation in COVID-19 (preprint)
A An, A Baghela, P Zhang, TM Blimkie, J Gauthier, DE Kaufmann, E Acton, ...
2023
Dynamic gene expression analysis reveals distinct severity phases of immune and cellular dysregulation in COVID-19
A An, A Baghela, P Zhang, TM Blimkie, J Gauthier, DE Kaufmann, E Acton, ...
bioRxiv, 2023.11. 04.565404, 2023
2023
Identifying predictive gene expression signatures of sepsis severity
A Baghela
University of British Columbia, 2022
2022
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Articles 1–18