Alex K. Shalek
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Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets
EZ Macosko, A Basu, R Satija, J Nemesh, K Shekhar, M Goldman, I Tirosh, ...
Cell 161 (5), 1202-1214, 2015
41812015
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
AP Patel, I Tirosh, JJ Trombetta, AK Shalek, SM Gillespie, H Wakimoto, ...
Science 344 (6190), 1396-1401, 2014
27232014
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ...
Science 352 (6282), 189-196, 2016
20612016
SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues
CGK Ziegler, SJ Allon, SK Nyquist, IM Mbano, VN Miao, CN Tzouanas, ...
Cell 181 (5), 1016-1035. e19, 2020
12982020
Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells
AK Shalek, R Satija, X Adiconis, RS Gertner, JT Gaublomme, ...
Nature 498 (7453), 236-240, 2013
10812013
Science forum: the human cell atlas
A Regev, SA Teichmann, ES Lander, I Amit, C Benoist, E Birney, ...
elife 6, e27041, 2017
10372017
MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data
G Finak, A McDavid, M Yajima, J Deng, V Gersuk, AK Shalek, CK Slichter, ...
Genome biology 16 (1), 1-13, 2015
9982015
Single-cell RNA-seq reveals dynamic paracrine control of cellular variation
AK Shalek, R Satija, J Shuga, JJ Trombetta, D Gennert, D Lu, P Chen, ...
Nature 510 (7505), 363-369, 2014
7882014
Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells
ML Suvà, E Rheinbay, SM Gillespie, AP Patel, H Wakimoto, SD Rabkin, ...
Cell 157 (3), 580-594, 2014
6752014
Dynamic regulatory network controlling TH 17 cell differentiation
N Yosef, AK Shalek, JT Gaublomme, H Jin, Y Lee, A Awasthi, C Wu, ...
Nature 496 (7446), 461-468, 2013
6152013
Vertical silicon nanowires as a universal platform for delivering biomolecules into living cells
AK Shalek, JT Robinson, ES Karp, JS Lee, DR Ahn, MH Yoon, A Sutton, ...
Proceedings of the National Academy of Sciences 107 (5), 1870-1875, 2010
5372010
Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer
JG Lohr, VA Adalsteinsson, K Cibulskis, AD Choudhury, M Rosenberg, ...
Nature biotechnology 32 (5), 479-484, 2014
5092014
Vertical nanowire electrode arrays as a scalable platform for intracellular interfacing to neuronal circuits
JT Robinson, M Jorgolli, AK Shalek, MH Yoon, RS Gertner, H Park
Nature nanotechnology 7 (3), 180-184, 2012
4992012
Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput
TM Gierahn, MH Wadsworth, TK Hughes, BD Bryson, A Butler, R Satija, ...
Nature methods 14 (4), 395-398, 2017
4742017
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade
L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ...
Cell 175 (4), 984-997. e24, 2018
4512018
Single-cell genomics unveils critical regulators of Th17 cell pathogenicity
JT Gaublomme, N Yosef, Y Lee, RS Gertner, LV Yang, C Wu, PP Pandolfi, ...
Cell 163 (6), 1400-1412, 2015
3962015
Transcriptional and epigenetic dynamics during specification of human embryonic stem cells
CA Gifford, MJ Ziller, H Gu, C Trapnell, J Donaghey, A Tsankov, ...
Cell 153 (5), 1149-1163, 2013
3932013
Deconstructing transcriptional heterogeneity in pluripotent stem cells
RM Kumar, P Cahan, AK Shalek, R Satija, AJ DaleyKeyser, H Li, J Zhang, ...
Nature 516 (7529), 56-61, 2014
3352014
Intra-and inter-cellular rewiring of the human colon during ulcerative colitis
CS Smillie, M Biton, J Ordovas-Montanes, KM Sullivan, G Burgin, ...
Cell 178 (3), 714-730. e22, 2019
3212019
Single-cell RNA-seq reveals AML hierarchies relevant to disease progression and immunity
P van Galen, V Hovestadt, MH Wadsworth II, TK Hughes, GK Griffin, ...
Cell 176 (6), 1265-1281. e24, 2019
2772019
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