Ideal cardiovascular health influences cardiovascular disease risk associated with high lipoprotein (a) levels and genotype: the EPIC-Norfolk prospective population study N Perrot, R Verbeek, M Sandhu, SM Boekholdt, GK Hovingh, ... Atherosclerosis 256, 47-52, 2017 | 92 | 2017 |
Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease N Ghodsian, E Abner, CA Emdin, E Gobeil, N Taba, ME Haas, N Perrot, ... Cell Reports Medicine 2 (11), 2021 | 85 | 2021 |
Genetic and In Vitro Inhibition of PCSK9 and Calcific Aortic Valve Stenosis N Perrot, V Valerio, D Moschetta, SM Boekholdt, C Dina, HY Chen, ... Basic to Translational Science 5 (7), 649-661, 2020 | 59 | 2020 |
Elevated lipoprotein (a) and risk of atrial fibrillation: an observational and Mendelian randomization study P Mohammadi-Shemirani, M Chong, S Narula, N Perrot, D Conen, ... Journal of the American College of Cardiology 79 (16), 1579-1590, 2022 | 54 | 2022 |
Genetic variation in LPA, calcific aortic valve stenosis in patients undergoing cardiac surgery, and familial risk of aortic valve microcalcification N Perrot, S Thériault, C Dina, HY Chen, SM Boekholdt, S Rigade, ... JAMA cardiology 4 (7), 620-627, 2019 | 49 | 2019 |
Lipoprotein (a), oxidized phospholipids, and aortic valve microcalcification assessed by 18F-sodium fluoride positron emission tomography and computed tomography AA Després, N Perrot, A Poulin, L Tastet, M Shen, HY Chen, R Bourgeois, ... CJC open 1 (3), 131-140, 2019 | 46 | 2019 |
GWAS and ExWAS of blood mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia M Chong, P Mohammadi-Shemirani, N Perrot, W Nelson, R Morton, ... Elife 11, e70382, 2022 | 44 | 2022 |
Association of long-term exposure to elevated lipoprotein (a) levels with parental life span, chronic disease–free survival, and mortality risk: a Mendelian randomization analysis BJ Arsenault, W Pelletier, Y Kaiser, N Perrot, C Couture, KT Khaw, ... JAMA network open 3 (2), e200129-e200129, 2020 | 35 | 2020 |
Life's simple 7 and calcific aortic valve stenosis incidence in apparently healthy men and women N Perrot, SM Boekholdt, P Mathieu, NJ Wareham, KT Khaw, BJ Arsenault International journal of cardiology 269, 226-228, 2018 | 33 | 2018 |
Polygenic risk score for coronary artery disease improves the prediction of early-onset myocardial infarction and mortality in men HD Manikpurage, A Eslami, N Perrot, Z Li, C Couture, P Mathieu, Y Bossé, ... Circulation: Genomic and Precision Medicine 14 (6), e003452, 2021 | 25 | 2021 |
Does lifestyle contribute to disease severity in patients with inherited lipid disorders? BJ Arsenault, N Perrot, P Couture Current Opinion in Lipidology 28 (2), 177-185, 2017 | 20 | 2017 |
Lipoprotein proteomics and aortic valve transcriptomics identify biological pathways linking lipoprotein (a) levels to aortic stenosis R Bourgeois, J Bourgault, AA Despres, N Perrot, J Guertin, A Girard, ... Metabolites 11 (7), 459, 2021 | 18 | 2021 |
Interaction of autotaxin with lipoprotein (a) in patients with calcific aortic valve stenosis R Bourgeois, R Devillers, N Perrot, AA Després, MC Boulanger, ... Basic to Translational Science 5 (9), 888-897, 2020 | 17 | 2020 |
Lipoprotein-associated phospholipase A2 activity, genetics and calcific aortic valve stenosis in humans N Perrot, S Thériault, S Rigade, HY Chen, C Dina, A Martinsson, ... Heart 106 (18), 1407-1412, 2020 | 15 | 2020 |
Therapeutic agents targeting cardiometabolic risk for preventing and treating atherosclerotic cardiovascular diseases BJ Arsenault, N Perrot, R Puri Clinical Pharmacology & Therapeutics 104 (2), 257-268, 2018 | 14 | 2018 |
A comparative analysis of the lipoprotein (a) and low-density lipoprotein proteomic profiles combining mass spectrometry and Mendelian randomization R Bourgeois, A Girard, N Perrot, J Guertin, PL Mitchell, C Couture, C Gotti, ... CJC open 3 (4), 450-459, 2021 | 13 | 2021 |
Sex-Specific Associations of Genetically Predicted Circulating Lp(a) (Lipoprotein(a)) and Hepatic LPA Gene Expression Levels With Cardiovascular Outcomes … J Guertin, Y Kaiser, H Manikpurage, N Perrot, R Bourgeois, C Couture, ... Circulation: Genomic and Precision Medicine 14 (4), e003271, 2021 | 11 | 2021 |
A trans‐omic Mendelian randomization study of parental lifespan uncovers novel aging biology and therapeutic candidates for chronic diseases N Perrot, W Pelletier, J Bourgault, C Couture, Z Li, PL Mitchell, ... Aging Cell 20 (11), e13497, 2021 | 9 | 2021 |
Circulating galectin-3 levels are not associated with nonalcoholic fatty liver disease: A mendelian randomization study M Tremblay, N Perrot, N Ghodsian, É Gobeil, C Couture, PL Mitchell, ... The Journal of Clinical Endocrinology & Metabolism 106 (8), e3178-e3184, 2021 | 7 | 2021 |
A versatile, fast and unbiased method for estimation of gene-by-environment interaction effects on biobank-scale datasets M Di Scipio, M Khan, S Mao, M Chong, C Judge, N Pathan, N Perrot, ... Nature Communications 14 (1), 5196, 2023 | 6 | 2023 |