A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity S Liang, E Tran, X Du, J Dong, H Sudholz, H Chen, Z Qu, ND Huntington, ... Nature Communications 14 (1), 4524, 2023 | 20 | 2023 |
Design and characterization of a heterobifunctional degrader of KEAP1 H Chen, NH Nguyen, CM Magtoto, SA Cobbold, GM Bidgood, ... Redox Biology 59, 102552, 2023 | 16 | 2023 |
The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells Z Wang, H Hu, L Heitink, K Rogers, Y You, T Tan, CLW Suen, A Garnham, ... Cell Death & Differentiation 30 (4), 1033-1046, 2023 | 15 | 2023 |
Live cell imaging of the TGF-β/Smad3 signaling pathway in vitro and in vivo using an adenovirus reporter system H Chen, TMB Ware, J Iaria, HJ Zhu JoVE (Journal of Visualized Experiments), e57926, 2018 | 10 | 2018 |
Late stage phosphotyrosine mimetic functionalization of peptides employing metallaphotoredox catalysis H Chen, R Mao, M Brzozowski, NH Nguyen, BE Sleebs Organic Letters 23 (11), 4244-4249, 2021 | 6 | 2021 |
Optimization of phosphotyrosine peptides that target the SH2 domain of SOCS1 and block substrate ubiquitination H Chen, Y Wu, K Li, I Currie, N Keating, F Dehkhoda, C Grohmann, ... ACS Chemical Biology 17 (2), 449-462, 2022 | 5 | 2022 |
Structure guided studies of the interaction between PTP1B and JAK R Morris, N Keating, C Tan, H Chen, A Laktyushin, T Saiyed, NPD Liau, ... Communications Biology 6 (1), 641, 2023 | 3 | 2023 |