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Hao Chen
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A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity
S Liang, E Tran, X Du, J Dong, H Sudholz, H Chen, Z Qu, ND Huntington, ...
Nature Communications 14 (1), 4524, 2023
202023
Design and characterization of a heterobifunctional degrader of KEAP1
H Chen, NH Nguyen, CM Magtoto, SA Cobbold, GM Bidgood, ...
Redox Biology 59, 102552, 2023
162023
The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells
Z Wang, H Hu, L Heitink, K Rogers, Y You, T Tan, CLW Suen, A Garnham, ...
Cell Death & Differentiation 30 (4), 1033-1046, 2023
152023
Live cell imaging of the TGF-β/Smad3 signaling pathway in vitro and in vivo using an adenovirus reporter system
H Chen, TMB Ware, J Iaria, HJ Zhu
JoVE (Journal of Visualized Experiments), e57926, 2018
102018
Late stage phosphotyrosine mimetic functionalization of peptides employing metallaphotoredox catalysis
H Chen, R Mao, M Brzozowski, NH Nguyen, BE Sleebs
Organic Letters 23 (11), 4244-4249, 2021
62021
Optimization of phosphotyrosine peptides that target the SH2 domain of SOCS1 and block substrate ubiquitination
H Chen, Y Wu, K Li, I Currie, N Keating, F Dehkhoda, C Grohmann, ...
ACS Chemical Biology 17 (2), 449-462, 2022
52022
Structure guided studies of the interaction between PTP1B and JAK
R Morris, N Keating, C Tan, H Chen, A Laktyushin, T Saiyed, NPD Liau, ...
Communications Biology 6 (1), 641, 2023
32023
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