Pimozide alleviates hyperglycemia in diet-induced obesity by inhibiting skeletal muscle ketone oxidation R Al Batran, K Gopal, ME Capozzi, JJ Chahade, B Saleme, ... Cell Metabolism 31 (5), 909-919. e8, 2020 | 56 | 2020 |
FoxO1 inhibition alleviates type 2 diabetes-related diastolic dysfunction by increasing myocardial pyruvate dehydrogenase activity K Gopal, R Al Batran, TR Altamimi, AA Greenwell, CT Saed, SAT Dakhili, ... Cell Reports 35 (1), 2021 | 50 | 2021 |
Untying the knot of transcription factor druggability: Molecular modeling study of FOXM1 inhibitors SA Tabatabaei-Dakhili, R Aguayo-Ortiz, L Domínguez, ... Journal of Molecular Graphics and Modelling 80, 197-210, 2018 | 33 | 2018 |
A structure-activity relationship study of Forkhead Domain Inhibitors (FDI): The importance of halogen binding interactions SAT Dakhili, DJ Pérez, K Gopal, SYT Dakhili, JR Ussher, ... Bioorganic chemistry 93, 103269, 2019 | 24 | 2019 |
SP1-independent inhibition of FOXM1 by modified thiazolidinediones SAT Dakhili, DJ Pérez, K Gopal, M Haque, JR Ussher, K Kashfi, ... European Journal of Medicinal Chemistry 209, 112902, 2021 | 22 | 2021 |
Aldose reductase inhibition alleviates diabetic cardiomyopathy and is associated with a decrease in myocardial fatty acid oxidation K Gopal, QG Karwi, SA Tabatabaei Dakhili, CS Wagg, L Zhang, Q Sun, ... Cardiovascular Diabetology 22 (1), 73, 2023 | 21 | 2023 |
Pyruvate dehydrogenase as a therapeutic target for nonalcoholic fatty liver disease CT Saed, SA Tabatabaei Dakhili, JR Ussher ACS Pharmacology & Translational Science 4 (2), 582-588, 2021 | 21 | 2021 |
Barth syndrome-related cardiomyopathy is associated with a reduction in myocardial glucose oxidation AA Greenwell, K Gopal, TR Altamimi, CT Saed, F Wang, ... American Journal of Physiology-Heart and Circulatory Physiology 320 (6 …, 2021 | 15 | 2021 |
The antipsychotic dopamine 2 receptor antagonist diphenylbutylpiperidines improve glycemia in experimental obesity by inhibiting succinyl-CoA: 3-ketoacid CoA transferase SA Tabatabaei Dakhili, AA Greenwell, K Yang, R Abou Farraj, CT Saed, ... Diabetes 72 (1), 126-134, 2023 | 11 | 2023 |
SNPs for genes encoding the mitochondrial proteins Sirtuin3 and uncoupling protein 2 are associated with disease severity, type 2 diabetes, and outcomes in patients with … Y Zhang, SD Zervopoulos, AE Boukouris, MA Lorenzana‐Carrillo, ... Journal of the American Heart Association 10 (23), e020451, 2021 | 11 | 2021 |
An isoproteic cocoa butter-based ketogenic diet fails to improve glucose homeostasis and promote weight loss in obese mice AA Greenwell, CT Saed, SAT Dakhili, KL Ho, K Gopal, JSF Chan, ... American Journal of Physiology-Endocrinology and Metabolism, 2022 | 10 | 2022 |
Myeloperoxidase-mediated oxidation of edaravone produces an apparent non-toxic free radical metabolite and modulates hydrogen peroxide-mediated cytotoxicity in HL-60 cells LYK Suh, D Babu, L Tonoyan, B Reiz, R Whittal, SA Tabatabaei-Dakhili, ... Free Radical Biology and Medicine 143, 422-432, 2019 | 10 | 2019 |
Ketone ester administration improves glycemia in obese mice SA Tabatabaei Dakhili, K Yang, CAA Locatelli, CT Saed, AA Greenwell, ... American Journal of Physiology-Cell Physiology 325 (3), C750-C757, 2023 | 9 | 2023 |
Biodistribution and activity of EGFR targeted polymeric micelles delivering a new inhibitor of DNA repair to Orthotopic colorectal Cancer xenografts with metastasis IM de Paiva, MR Vakili, AH Soleimani, SA Tabatabaei Dakhili, S Munira, ... Molecular Pharmaceutics 19 (6), 1825-1838, 2022 | 8 | 2022 |
Defective muscle ketone body oxidation disrupts BCAA catabolism by altering mitochondrial branched-chain aminotransferase H Mechchate, AM Abdualkader, JB Bernacchi, K Gopal, ... American Journal of Physiology-Endocrinology and Metabolism 324 (5), E425-E436, 2023 | 7 | 2023 |
Pyruvate dehydrogenase complex and glucose oxidation as a therapeutic target in diabetic heart disease SAT Dakhili, AA Greenwell, JR Ussher Journal of Lipid and Atherosclerosis 12 (1), 47, 2022 | 7 | 2022 |
Structure–Activity Relationship of N-Phenylthieno[2,3-b]pyridine-2-carboxamide Derivatives Designed as Forkhead Box M1 Inhibitors: The Effect of Electron … CS Huerta-García, DJ Pérez, CA Velázquez-Martínez, ... Pharmaceuticals 15 (3), 283, 2022 | 7 | 2022 |
Reversible and irreversible inhibitors of coronavirus Nsp15 endoribonuclease J Chen, R Abou Farraj, D Limonta, SAT Dakhili, EM Kerek, ... Journal of Biological Chemistry 299 (11), 2023 | 6 | 2023 |
The therapeutic potential of ketones in cardiometabolic disease: impact on heart and skeletal muscle S Soni, SA Tabatabaei Dakhili, JR Ussher, JRB Dyck American Journal of Physiology-Cell Physiology 326 (2), C551-C566, 2024 | 4 | 2024 |
FOXM1 Inhibitors as Potential Diagnostic Agents: First Generation of a PET Probe Targeting FOXM1 To Detect Triple‐Negative Breast Cancer in vitro and in vivo DJ Pérez, S Amirhossein Tabatabaei Dakhili, C Bergman, J Dufour, ... ChemMedChem 16 (24), 3720-3729, 2021 | 4 | 2021 |