| Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia R Tirtakusuma, K Szoltysek, P Milne, VV Grinev, A Ptasinska, PS Chin, ... Blood, The Journal of the American Society of Hematology 140 (17), 1875-1890, 2022 | 33 | 2022 |
| PLCG1 is required for AML1-ETO leukemia stem cell self-renewal TM Schnoeder, A Schwarzer, AK Jayavelu, CJ Hsu, J Kirkpatrick, ... Blood, The Journal of the American Society of Hematology 139 (7), 1080-1097, 2022 | 17 | 2022 |
| Different mutant RUNX1 oncoproteins program alternate haematopoietic differentiation trajectories SG Kellaway, P Keane, B Edginton-White, K Regha, E Kennett, C Bonifer Life Science Alliance 4 (2), 2021 | 17 | 2021 |
| A genome-wide relay of signalling-responsive enhancers drives hematopoietic specification B Edginton-White, A Maytum, SG Kellaway, DK Goode, P Keane, ... Nature Communications 14 (1), 267, 2023 | 12 | 2023 |
| Molecular basis of hematological disease caused by inherited or acquired RUNX1 mutations SG Kellaway, DJL Coleman, PN Cockerill, M Raghavan, C Bonifer Experimental Hematology 111, 1-12, 2022 | 12 | 2022 |
| RUNX1-EVI1 disrupts lineage determination and the cell cycle by interfering with RUNX1 and EVI1 driven gene regulatory networks SG Kellaway, P Keane, E Kennett, C Bonifer haematologica 106 (6), 1569, 2021 | 11 | 2021 |
| t (8; 21) acute myeloid leukemia as a paradigm for the understanding of leukemogenesis at the level of gene regulation and chromatin programming S Kellaway, PS Chin, F Barneh, C Bonifer, O Heidenreich Cells 9 (12), 2681, 2020 | 10 | 2020 |
| Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia A Adamo, P Chin, P Keane, SA Assi, S Potluri, SG Kellaway, D Coleman, ... Leukemia 37 (1), 102-112, 2023 | 6 | 2023 |
| Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth DJL Coleman, P Keane, R Luque-Martin, PS Chin, H Blair, L Ames, ... Cell reports 42 (12), 2023 | 4 | 2023 |
| Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth SG Kellaway, S Potluri, P Keane, HJ Blair, L Ames, A Worker, PS Chin, ... Nature Communications 15 (1), 1359, 2024 | 3* | 2024 |
| Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism SG Kellaway, K Mosinska, Z Mohamed, A Ryan, S Richardson, ... Plos one 14 (9), e0222350, 2019 | 3 | 2019 |
| Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1 DJL Coleman, P Keane, PS Chin, L Ames, S Kellaway, H Blair, N Khan, ... Iscience 27 (4), 2024 | | 2024 |
| Gene regulation in t (6; 9) DEK:: NUP214 Acute Myeloid Leukemia resembles that of FLT3-ITD/NPM1 Acute Myeloid Leukemia but with an altered HOX/MEIS axis S Potluri, SG Kellaway, DJL Coleman, P Keane, MR Imperato, SA Assi, ... Leukemia, 1-5, 2024 | | 2024 |
Peter KeaneUniversity of BirminghamVerified email at bham.ac.uk
