| Optimized delivery of siRNA into 3D tumor spheroid cultures in situ RG Morgan, AC Chambers, DN Legge, SJ Coles, A Greenhough, ... Scientific reports 8 (1), 7952, 2018 | 34 | 2018 |
| BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells DN Legge, AP Shephard, TJ Collard, A Greenhough, AC Chambers, ... Disease Models & Mechanisms 12 (3), dmm037697, 2019 | 30 | 2019 |
| The role of B-Cell Lymphoma-3 (BCL-3) in enabling the hallmarks of cancer: implications for the treatment of colorectal carcinogenesis DN Legge, AC Chambers, CT Parker, P Timms, TJ Collard, AC Williams Carcinogenesis 41 (3), 249-256, 2020 | 26 | 2020 |
| Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study M Gormley, J Yarmolinsky, T Dudding, K Burrows, RM Martin, S Thomas, ... PLoS Genetics 17 (4), e1009525, 2021 | 16 | 2021 |
| LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity RG Morgan, E Mortensson, DN Legge, B Gupta, TJ Collard, ... British journal of cancer 118 (4), 558-565, 2018 | 15 | 2018 |
| 5-Aminosalicylic acid inhibits stem cell function in human adenoma-derived cells: implications for chemoprophylaxis in colorectal tumorigenesis SW Dixon, TJ Collard, EMH Mortensson, DN Legge, AC Chambers, ... British Journal of Cancer 124 (12), 1959-1969, 2021 | 11 | 2021 |
| Evaluating the effect of metabolic traits on oral and oropharyngeal cancer risk using Mendelian randomization M Gormley, T Dudding, SJ Thomas, J Tyrrell, AR Ness, M Pring, D Legge, ... Elife 12, e82674, 2023 | 10 | 2023 |
| The epithelial splicing regulator ESRP2 is epigenetically repressed by DNA hypermethylation in Wilms tumour and acts as a tumour suppressor D Legge, L Li, W Moriarty, D Lee, M Szemes, A Zahed, L Panousopoulos, ... Molecular Oncology 16 (3), 630-647, 2022 | 4 | 2022 |
| Aspirin and the metabolic hallmark of cancer: novel therapeutic opportunities for colorectal cancer AJ Hoskin, AK Holt, DN Legge, TJ Collard, AC Williams, EE Vincent Exploration of Targeted Anti-tumor Therapy 4 (4), 600, 2023 | 3 | 2023 |
| In-silico and in-vitro morphometric analysis of intestinal organoids S Montes-Olivas, D Legge, A Lund, AG Fletcher, AC Williams, L Marucci, ... PLoS Computational Biology 19 (8), e1011386, 2023 | 2 | 2023 |
| Identifying metabolic features of colorectal cancer liability using Mendelian randomization C Bull, E Hazelwood, JA Bell, V Tan, AE Constantinescu, C Borges, ... Elife 12, RP87894, 2023 | 1 | 2023 |
| Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition AK Holt, AK Najumudeen, TJ Collard, H Li, LM Millett, AJ Hoskin, ... Cancer & Metabolism 11 (1), 18, 2023 | 1 | 2023 |
| Glutamine addiction is targetable via altering splicing of nutrient sensors and epitranscriptome regulators J Bojko, M Kollareddy, M Szemes, J Bellamy, E Poon, A Moukachar, ... bioRxiv, 2024.02. 28.582087, 2024 | | 2024 |
| Impact of weight loss on cancer-related proteins in serum: results from a cluster randomised controlled trial of individuals with type 2 diabetes CJ Bull, E Hazelwood, DN Legge, LJ Corbin, TG Richardson, M Lee, ... EBioMedicine 100, 2024 | | 2024 |
| In-silicoandin-vitromorphometric analysis of intestinal organoids S Montes-Olivas, D Legge, A Lund, AG Fletcher, AC Williams, L Marucci, ... | | 2022 |
| The effect of metabolic traits on oral and oropharyngeal cancer risk: a Mendelian randomization analysis M Gormley, T Dudding, SJ Thomas, J Tyrrell, AR Ness, M Pring, D Legge, ... medRxiv, 2022.08. 10.22278617, 2022 | | 2022 |
| Identifying targetable metabolic dependencies across colorectal cancer progression DN Legge, E Stanko, AK Holt, CJ Bull, TJ Collard, M Kollareddy, ... bioRxiv, 2022.03. 23.485483, 2022 | | 2022 |
| First person–Danny Legge D Legge Disease Models & Mechanisms 12 (3), 2019 | | 2019 |
| First posted online on 21 February 2019 as 10.1242/dmm. 037697 DN Legge, AP Shephard, TJ Collard, A Greenhough, AC Chambers, ... | | 2019 |
| Investigating the role of BCL-3 in promoting a cancer stem cell phenotype in colorectal cancer DN Legge University of Bristol, 2018 | | 2018 |
