Hyperphysiological compression of articular cartilage induces an osteoarthritic phenotype in a cartilage-on-a-chip model P Occhetta, A Mainardi, E Votta, Q Vallmajo-Martin, M Ehrbar, I Martin, ... Nature biomedical engineering 3 (7), 545-557, 2019 | 162 | 2019 |
Chondrocyte hypertrophy in osteoarthritis: mechanistic studies and models for the identification of new therapeutic strategies S Chawla, A Mainardi, N Majumder, L Dönges, B Kumar, P Occhetta, ... Cells 11 (24), 4034, 2022 | 23 | 2022 |
Generation of functional cardiac microtissues in a beating heart-on-a-chip GS Ugolini, R Visone, D Cruz-Moreira, A Mainardi, M Rasponi Methods in cell biology 146, 69-84, 2018 | 21 | 2018 |
A dynamic microscale mid-throughput fibrosis model to investigate the effects of different ratios of cardiomyocytes and fibroblasts A Mainardi, F Carminati, GS Ugolini, P Occhetta, G Isu, DR Diaz, G Reid, ... Lab on a Chip 21 (21), 4177-4195, 2021 | 17 | 2021 |
Intervertebral Disc-on-a-Chip as Advanced In Vitro Model for Mechanobiology Research and Drug Testing: A Review and Perspective A Mainardi, E Cambria, P Occhetta, I Martin, A Barbero, S Schären, ... Frontiers in Bioengineering and Biotechnology 9, 826867, 2022 | 12 | 2022 |
Modeling in vitro osteoarthritis phenotypes in a vascularized bone model based on a bone-marrow derived mesenchymal cell line and endothelial cells A Pirosa, EB Tankus, A Mainardi, P Occhetta, L Dönges, C Baum, ... International Journal of Molecular Sciences 22 (17), 9581, 2021 | 9 | 2021 |
Cholangiocarcinoma-on-a-chip: A human 3D platform for personalised medicine MA Polidoro, E Ferrari, C Soldani, B Franceschini, G Saladino, A Rosina, ... JHEP Reports 6 (1), 100910, 2024 | 3 | 2024 |
Mechanical induction of osteoarthritis traits in a cartilage-on-a-chip model A Mainardi, P Occhetta, M Rasponi Organ-on-a-Chip: Methods and Protocols, 231-251, 2022 | 2 | 2022 |
Towards Modelling The Joint On A Chip: A Mechanically Active Microfluidic System Designed For Engineered 3d Multi-Layer Osteochondral Tissues A Mainardi, P Occhetta, I Martin, M Rasponi, A Barbero Osteoarthritis and Cartilage 31, S56-S57, 2023 | 1 | 2023 |
Organ-on-chips for studying tissue barriers: standard techniques and a novel method for including porous membranes within microfluidic devices M Ballerini, M Jouybar, A Mainardi, M Rasponi, GS Ugolini Organ-on-a-Chip: Methods and Protocols, 21-38, 2022 | 1 | 2022 |
Beating organs-on-chips as advanced preclinical tools for drug screening and disease modelling P Occhetta, R Visone, A Mainardi, S Piazza, A Barbero, M Rasponi E-Abstracts-EUROoCs-2020, 156-156, 2020 | 1 | 2020 |
Towards the knee on a chip: development of a microfluidic platform for the mechanical stimulation of three dimensional cartilaginous constructs A Mainardi, P Occhetta, E Votta, M Rasponi Politecnico di Milano, 2015 | 1 | 2015 |
Engineered human osteoarthritic cartilage organoids L Dönges, A Damle, A Mainardi, T Bock, M Schönenberger, I Martin, ... Biomaterials 308, 122549, 2024 | | 2024 |
Design and development of an Organ-on-Chip model to study the role of mechanical stimuli on cartilage development and pathological onset E Monti, A Mainardi, C Palma, A Barbero, M Rasponi, P Occhetta Osteoarthritis and Cartilage 32, S285-S286, 2024 | | 2024 |
A NASAL CHONDROCYTE-BASED INFLAMMATION RESISTANT THERAPY APPROACH FOR OSTEOARTHRITIS A Damle, K Sovdagarova, B Dasen, C Egloff, I Martin, A Mainardi, ... Osteoarthritis and Cartilage 32, S384, 2024 | | 2024 |
3D bioprinting of a hypoxia-gradient for generating heterogenous cartilage scaffolds EB Tankusi, G Miklosic, A Mainardi, N Sharma, MD Este, A Barbero, ... TISSUE ENGINEERING PART A 29 (13-14), 2023 | | 2023 |
Towards modeling the joint on a chip: a mechanically active microfluidic system to engineer 3D multi-layer osteochondral tissues A Mainardi, P Occhetta, M Ehrbar, I Martin, A Barbero, EB Tankus TISSUE ENGINEERING PART A 29 (13-14), 2023 | | 2023 |
Modelling Osteoarthritis pathogenesis through Mechanical Loading in an Osteochondral Unit-on-Chip A Mainardi, A Boersch, P Occhetta, R Ivanek, M Ehrbar, LA Krattiger, ... bioRxiv, 2023.08. 29.555292, 2023 | | 2023 |
DEVELOPMENT OF A VASCULARISED BONE MODEL TO STUDY ROLE OF VASCULATURE ON OSTEOARTHRITIS ONSET A Pirosa, A Mainardi, P Occhetta, M Erhbar, I Martin, M Rasponi, ... TISSUE ENGINEERING PART A 28, S69-S70, 2022 | | 2022 |
BEATING ORGANS-ON-CHIPS AS ADVANCED PRECLINICAL TOOLS FOR DRUG SCREENING AND DISEASE MODELLING APPLICATIONS P Occhetta, R Visone, A Mainardi, A Barbero, M Rasponi TISSUE ENGINEERING PART A 28, S25-S25, 2022 | | 2022 |