| Biobank-driven genomic discovery yields new insight into atrial fibrillation biology JB Nielsen, RB Thorolfsdottir, LG Fritsche, W Zhou, MW Skov, SE Graham, ... Nature genetics 50 (9), 1234-1239, 2018 | 598 | 2018 |
| Computationally efficient whole-genome regression for quantitative and binary traits J Mbatchou, L Barnard, J Backman, A Marcketta, JA Kosmicki, ... Nature genetics 53 (7), 1097-1103, 2021 | 554 | 2021 |
| Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure S Shah, A Henry, C Roselli, H Lin, G Sveinbjörnsson, G Fatemifar, ... Nature communications 11 (1), 163, 2020 | 534 | 2020 |
| Exome sequencing and analysis of 454,787 UK Biobank participants JD Backman, AH Li, A Marcketta, D Sun, J Mbatchou, MD Kessler, ... Nature 599 (7886), 628-634, 2021 | 450 | 2021 |
| Exome sequencing and characterization of 49,960 individuals in the UK Biobank CV Van Hout, I Tachmazidou, JD Backman, JD Hoffman, D Liu, ... Nature 586 (7831), 749-756, 2020 | 392 | 2020 |
| Whole exome sequencing and characterization of coding variation in 49,960 individuals in the UK Biobank CV Van Hout, I Tachmazidou, JD Backman, JX Hoffman, B Ye, AK Pandey, ... BioRxiv, 572347, 2019 | 110 | 2019 |
| Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease JE Horowitz, JA Kosmicki, A Damask, D Sharma, GHL Roberts, AE Justice, ... Nature genetics 54 (4), 382-392, 2022 | 107 | 2022 |
| Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals JA Kosmicki, JE Horowitz, N Banerjee, R Lanche, A Marcketta, E Maxwell, ... The American Journal of Human Genetics 108 (7), 1350-1355, 2021 | 82 | 2021 |
| Pharmacogenomic polygenic response score predicts ischaemic events and cardiovascular mortality in clopidogrel-treated patients JP Lewis, JD Backman, JL Reny, TO Bergmeijer, BD Mitchell, MD Ritchie, ... European Heart Journal-Cardiovascular Pharmacotherapy 6 (4), 203-210, 2020 | 79 | 2020 |
| Genomewide association study of platelet reactivity and cardiovascular response in patients treated with clopidogrel: a study by the international clopidogrel pharmacogenomics … SS Verma, TO Bergmeijer, LI Gong, JL Reny, JP Lewis, BD Mitchell, ... Clinical Pharmacology & Therapeutics 108 (5), 1067-1077, 2020 | 42 | 2020 |
| Genetic variation in the platelet endothelial aggregation receptor 1 gene results in endothelial dysfunction AS Fisch, LM Yerges-Armstrong, JD Backman, H Wang, P Donnelly, ... PLoS One 10 (9), e0138795, 2015 | 35 | 2015 |
| Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure MG Levin, NL Tsao, P Singhal, C Liu, HMT Vy, I Paranjpe, JD Backman, ... Nature Communications 13 (1), 6914, 2022 | 31 | 2022 |
| Prospective evaluation of genetic variation in platelet endothelial aggregation receptor 1 reveals aspirin‐dependent effects on platelet aggregation pathways JD Backman, LM Yerges‐Armstrong, RB Horenstein, S Newcomer, ... Clinical and Translational Science 10 (2), 102-109, 2017 | 29 | 2017 |
| Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response JD Backman, JR O’Connell, K Tanner, CJ Peer, WD Figg, SD Spencer, ... Pharmacogenetics and genomics 27 (4), 159-163, 2017 | 26 | 2017 |
| Common genetic variants identify therapeutic targets for COVID-19 and individuals at high risk of severe disease JE Horowitz, JA Kosmicki, A Damask, D Sharma, GHL Roberts, AE Justice, ... MedRxiv, 2020 | 23 | 2020 |
| Genome-wide analysis in 756,646 individuals provides first genetic evidence that ACE2 expression influences COVID-19 risk and yields genetic risk scores predictive of severe … JE Horowitz, JA Kosmicki, A Damask, D Sharma, GHL Roberts, AE Justice, ... MedRxiv, 2021 | 20 | 2021 |
| MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk I Surakka, LG Fritsche, W Zhou, J Backman, JA Kosmicki, H Lu, ... Nature communications 11 (1), 4093, 2020 | 20 | 2020 |
| Exome-chip meta-analysis identifies association between variation in ANKRD26 and platelet aggregation MH Chen, LR Yanek, JD Backman, JD Eicher, JE Huffman, Y Ben-Shlomo, ... Platelets 30 (2), 164-173, 2019 | 18 | 2019 |
| A catalog of associations between rare coding variants and COVID-19 outcomes JA Kosmicki, JE Horowitz, N Banerjee, R Lanche, A Marcketta, E Maxwell, ... medRxiv, 2021 | 16 | 2021 |
| From Genotype to Phenotype: Nonsense Variants in SLC13A1 Are Associated with Decreased Serum Sulfate and Increased Serum Aminotransferases CG Tise, JA Perry, LE Anforth, MA Pavlovich, JD Backman, KA Ryan, ... G3: Genes, Genomes, Genetics 6 (9), 2909-2918, 2016 | 16 | 2016 |
