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ayşegül DURAK
ayşegül DURAK
Verified email at ankara.edu.tr
Title
Cited by
Cited by
Year
A SGLT2 inhibitor dapagliflozin suppresses prolonged ventricular-repolarization through augmentation of mitochondrial function in insulin-resistant metabolic syndrome rats
A Durak, Y Olgar, S Degirmenci, E Akkus, E Tuncay, B Turan
Cardiovascular diabetology 17, 1-17, 2018
1402018
Hyperglycemia-induced changes in ZIP7 and ZnT7 expression cause Zn2+ release from the sarco (endo) plasmic reticulum and mediate ER stress in the heart
E Tuncay, VC Bitirim, A Durak, GRJ Carrat, KM Taylor, GA Rutter, B Turan
Diabetes 66 (5), 1346-1358, 2017
792017
Aging related functional and structural changes in the heart and aorta: MitoTEMPO improves aged-cardiovascular performance
Y Olgar, S Degirmenci, A Durak, D Billur, B Can, G Kayki-Mutlu, B Turan
Experimental Gerontology 110, 172-181, 2018
592018
Zn2+-transporters ZIP7 and ZnT7 play important role in progression of cardiac dysfunction via affecting sarco (endo) plasmic reticulum-mitochondria coupling in hyperglycemic …
E Tuncay, CV Bitirim, Y Olgar, A Durak, GA Rutter, B Turan
Mitochondrion 44, 41-52, 2019
482019
Electrophysiological basis of metabolic-syndrome-induced cardiac dysfunction
EN Okatan, AT Durak, B Turan
Canadian journal of physiology and pharmacology 94 (10), 1064-1073, 2016
392016
Enhancement of Cellular Antioxidant-Defence Preserves Diastolic Dysfunction via Regulation of Both Diastolic Zn2+ and Ca2+ and Prevention of RyR2-Leak …
E Tuncay, EN Okatan, A Toy, B Turan
Oxidative Medicine and Cellular Longevity 2014, 2014
342014
The relationship between metabolic syndrome development and tissue trace elements status and inflammatory markers
S Akdas, B Turan, A Durak, P Aribal Ayral, N Yazihan
Biological Trace Element Research 198, 16-24, 2020
292020
Increased free Zn2+ correlates induction of sarco(endo)plasmic reticulum stress via altered expression levels of Zn2+‐transporters in heart failure
Y Olgar, A Durak, E Tuncay, CV Bitirim, E Ozcinar, MB Inan, ...
Journal of Cellular and Molecular Medicine 22 (3), 1944-1956, 2018
292018
Onset of decreased heart work is correlated with increased heart rate and shortened QT interval in high-carbohydrate fed overweight rats
A Durak, Y Olgar, E Tuncay, I Karaomerlioglu, G Kayki Mutlu, ...
Canadian Journal of Physiology and Pharmacology 95 (11), 1335-1342, 2017
272017
Beta-blocker timolol alleviates hyperglycemia-induced cardiac damage via inhibition of endoplasmic reticulum stress
FA Cicek, A Toy, E Tuncay, B Can, B Turan
Journal of bioenergetics and biomembranes 46, 377-387, 2014
272014
Interplay Between Cytosolic Free Zn2+ and Mitochondrion Morphological Changes in Rat Ventricular Cardiomyocytes
D Billur, E Tuncay, EN Okatan, Y Olgar, AT Durak, S Degirmenci, B Can, ...
Biological trace element research 174, 177-188, 2016
222016
Titin and CK2α are new intracellular targets in acute insulin application-associated benefits on electrophysiological parameters of left ventricular cardiomyocytes from insulin …
A Durak, CV Bitirim, B Turan
Cardiovascular drugs and therapy 34, 487-501, 2020
202020
Cytosolic increased labile Zn2+ contributes to arrhythmogenic action potentials in left ventricular cardiomyocytes through protein thiol oxidation and cellular ATP depletion
S Degirmenci, Y Olgar, A Durak, E Tuncay, B Turan
Journal of Trace Elements in Medicine and Biology 48, 202-212, 2018
202018
Glucagon‐like peptide‐1 receptor agonist treatment of high carbohydrate intake‐induced metabolic syndrome provides pleiotropic effects on cardiac dysfunction through …
A Durak, E Akkus, AG Canpolat, E Tuncay, D Corapcioglu, B Turan
Clinical and Experimental Pharmacology and Physiology 49 (1), 46-59, 2022
142022
Ticagrelor reverses the mitochondrial dysfunction through preventing accumulated autophagosomes-dependent apoptosis and ER stress in insulin-resistant H9c2 myocytes
Y Olgar, E Tuncay, D Billur, A Durak, S Ozdemir, B Turan
Molecular and Cellular Biochemistry 469, 97-107, 2020
112020
Insulin acts as an atypical KCNQ1/KCNE1‐current activator and reverses long QT in insulin‐resistant aged rats by accelerating the ventricular action potential repolarization …
Y Olgar, A Durak, CV Bitirim, E Tuncay, B Turan
Journal of Cellular Physiology 237 (2), 1353-1371, 2022
102022
Liraglutide provides cardioprotection through the recovery of mitochondrial dysfunction and oxidative stress in aging hearts
A Durak, B Turan
Journal of physiology and biochemistry 79 (2), 297-311, 2023
82023
β3‐adrenergic receptor activation plays an important role in the depressed myocardial contractility via both elevated levels of cellular free Zn2+ and reactive …
E Tuncay, Y Olgar, A Durak, S Degirmenci, CV Bitirim, B Turan
Journal of Cellular Physiology 234 (8), 13370-13386, 2019
82019
Intermittent hypoxia induces beneficial cardiovascular remodeling in left ventricular function of type 1 diabetic rat
F Akat, H Ficicilar, A Durak, E Tuncay, A Dursun, F Topal Çelikkan, ...
Anatolian Journal of Cardiology 19 (4), 2018
82018
Theoretical studies on the inactivation mechanism of γ-aminobutyric acid aminotransferase
AT Durak, H Gökcan, FAS Konuklar
Organic & Biomolecular Chemistry 9 (14), 5162-5171, 2011
82011
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