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Kerensa Broersen
Kerensa Broersen
Universiteit Twente, MIRA Instituut
Verified email at utwente.nl
Title
Cited by
Cited by
Year
Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio
I Kuperstein, K Broersen, I Benilova, J Rozenski, W Jonckheere, ...
The EMBO journal 29 (19), 3408-3420, 2010
6282010
The mechanism of γ‐secretase dysfunction in familial Alzheimer disease
L Chávez‐Gutiérrez, L Bammens, I Benilova, A Vandersteen, M Benurwar, ...
The EMBO journal 31 (10), 2261-2274, 2012
5962012
Structural basis for increased toxicity of pathological aβ42: aβ40 ratios in Alzheimer disease
K Pauwels, TL Williams, KL Morris, W Jonckheere, A Vandersteen, ...
Journal of biological chemistry 287 (8), 5650-5660, 2012
2832012
The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?
K Broersen, F Rousseau, J Schymkowitz
Alzheimer's research & therapy 2 (4), 1-14, 2010
1712010
Molecular mechanisms and genetics of oxidative stress in Alzheimer’s disease
F Cioffi, RHI Adam, K Broersen
Journal of Alzheimer's Disease 72 (4), 981-1017, 2019
1662019
A standardized and biocompatible preparation of aggregate-free amyloid beta peptide for biophysical and biological studies of Alzheimer's disease
K Broersen, W Jonckheere, J Rozenski, A Vandersteen, K Pauwels, ...
Protein Engineering, Design & Selection 24 (9), 743-750, 2011
1462011
Amyloid precursor protein mutation E682K at the alternative β‐secretase cleavage β′‐site increases Aβ generation
L Zhou, N Brouwers, I Benilova, A Vandersteen, M Mercken, K Van Laere, ...
EMBO molecular medicine 3 (5), 291-302, 2011
1312011
Glycoforms of β‐lactoglobulin with improved thermostability and preserved structural packing
K Broersen, AGJ Voragen, RJ Hamer, HHJ De Jongh
Biotechnology and Bioengineering 86 (1), 78-87, 2004
1132004
Mechanism of arachidonic acid action on syntaxin–Munc18
E Connell, F Darios, K Broersen, N Gatsby, SY Peak‐Chew, C Rickman, ...
EMBO reports 8 (4), 414-419, 2007
1082007
α-Synuclein adopts an α-helical conformation in the presence of polyunsaturated fatty acids to hinder micelle formation
K Broersen, D Van Den Brink, G Fraser, M Goedert, B Davletov
Biochemistry 45 (51), 15610-15616, 2006
932006
Transient dynamics of Aβ contribute to toxicity in Alzheimer’s disease
E Hubin, NAJ Van Nuland, K Broersen, K Pauwels
Cellular and Molecular Life Sciences 71, 3507-3521, 2014
872014
A comparative analysis of the aggregation behavior of amyloid-β peptide variants
A Vandersteen, E Hubin, R Sarroukh, G De Baets, J Schymkowitz, ...
FEBS letters 586 (23), 4088-4093, 2012
872012
Do sulfhydryl groups affect aggregation and gelation properties of ovalbumin?
K Broersen, AMM Van Teeffelen, A Vries, AGJ Voragen, RJ Hamer, ...
Journal of agricultural and food chemistry 54 (14), 5166-5174, 2006
812006
Alzheimer’s disease: Treatment strategies and their limitations
E Passeri, K Elkhoury, M Morsink, K Broersen, M Linder, A Tamayol, ...
International journal of molecular sciences 23 (22), 13954, 2022
792022
Optimized Triton X-114 assisted lipopolysaccharide (LPS) removal method reveals the immunomodulatory effect of food proteins
M Teodorowicz, O Perdijk, I Verhoek, C Govers, HFJ Savelkoul, Y Tang, ...
PloS one 12 (3), e0173778, 2017
772017
Glucosylation of β‐lactoglobulin lowers the heat capacity change of unfolding; a unique way to affect protein thermodynamics
AMM Van Teeffelen, K Broersen, HHJ de Jongh
Protein Science 14 (8), 2187-2194, 2005
622005
Mechanistic insights in glycation-induced protein aggregation
M Adrover, L Mariño, P Sanchis, K Pauwels, Y Kraan, P Lebrun, ...
Biomacromolecules 15 (9), 3449-3462, 2014
572014
Molecular plasticity regulates oligomerization and cytotoxicity of the multipeptide-length amyloid-β peptide pool
A Vandersteen, MF Masman, G De Baets, W Jonckheere, K Van Der Werf, ...
Journal of biological chemistry 287 (44), 36732-36743, 2012
522012
Multiplexed blood–brain barrier organ-on-chip
M Zakharova, MAP Do Carmo, MW Van Der Helm, MNS de Graaf, ...
Lab on a Chip 20 (17), 3132-3143, 2020
492020
Chemical processing as a tool to generate ovalbumin variants with changed stability
HA Kosters, K Broersen, J De Groot, JWFA Simons, P Wierenga, ...
Biotechnology and bioengineering 84 (1), 61-70, 2003
482003
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Articles 1–20