Laurence Cooper
Laurence Cooper
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CD28 costimulation provided through a CD19-specific chimeric antigen receptor enhances in vivo persistence and antitumor efficacy of adoptively transferred T cells
CM Kowolik, MS Topp, S Gonzalez, T Pfeiffer, S Olivares, N Gonzalez, ...
Cancer research 66 (22), 10995-11004, 2006
Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism
H Zhao, L Yang, J Baddour, A Achreja, V Bernard, T Moss, JC Marini, ...
elife 5, e10250, 2016
Antitransgene rejection responses contribute to attenuated persistence of adoptively transferred CD20/CD19-specific chimeric antigen receptor redirected T cells in humans
MC Jensen, L Popplewell, LJ Cooper, D DiGiusto, M Kalos, JR Ostberg, ...
Biology of blood and marrow transplantation 16 (9), 1245-1256, 2010
Transplantation of ex vivo expanded cord blood
EJ Shpall, R Quinones, R Giller, C Zeng, AE Baron, RB Jones, ...
Biology of Blood and Marrow Transplantation 8 (7), 368-376, 2002
A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR
H Torikai, A Reik, PQ Liu, Y Zhou, L Zhang, S Maiti, H Huls, JC Miller, ...
Blood, The Journal of the American Society of Hematology 119 (24), 5697-5705, 2012
Cord-blood engraftment with ex vivo mesenchymal-cell coculture
M De Lima, I McNiece, SN Robinson, M Munsell, M Eapen, M Horowitz, ...
New England Journal of Medicine 367 (24), 2305-2315, 2012
Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells
CJ Denman, VV Senyukov, SS Somanchi, PV Phatarpekar, LM Kopp, ...
PloS one 7 (1), e30264, 2012
Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor
B Jena, G Dotti, LJN Cooper
Blood, The Journal of the American Society of Hematology 116 (7), 1035-1044, 2010
Specific recognition and killing of glioblastoma multiforme by interleukin 13-zetakine redirected cytolytic T cells
KS Kahlon, C Brown, LJN Cooper, A Raubitschek, SJ Forman, ...
Cancer research 64 (24), 9160-9166, 2004
Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells
P Kebriaei, H Singh, MH Huls, MJ Figliola, R Bassett, S Olivares, B Jena, ...
The Journal of clinical investigation 126 (9), 3363-3376, 2016
Delayed immune reconstitution after cord blood transplantation is characterized by impaired thymopoiesis and late memory T-cell skewing
KV Komanduri, LS St. John, M De Lima, J McMannis, S Rosinski, ...
Blood, The Journal of the American Society of Hematology 110 (13), 4543-4551, 2007
T-cell clones can be rendered specific for CD19: Toward the selective augmentation of the graft-versus-B–lineage leukemia effect
LJN Cooper, MS Topp, LM Serrano, S Gonzalez, WC Chang, A Naranjo, ...
Blood, The Journal of the American Society of Hematology 101 (4), 1637-1644, 2003
Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system
H Singh, PR Manuri, S Olivares, N Dara, MJ Dawson, H Huls, PB Hackett, ...
Cancer research 68 (8), 2961-2971, 2008
Tuning sensitivity of CAR to EGFR density limits recognition of normal tissue while maintaining potent antitumor activity
HG Caruso, LV Hurton, A Najjar, D Rushworth, S Ang, S Olivares, T Mi, ...
Cancer research 75 (17), 3505-3518, 2015
Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype
K Gabrusiewicz, B Rodriguez, J Wei, Y Hashimoto, LM Healy, SN Maiti, ...
JCI insight 1 (2), 2016
A transposon and transposase system for human application
PB Hackett, DA Largaespada, LJN Cooper
Molecular therapy 18 (4), 674-683, 2010
Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer
BA Rabinovich, Y Ye, T Etto, JQ Chen, HI Levitsky, WW Overwijk, ...
Proceedings of the National Academy of Sciences 105 (38), 14342-14346, 2008
Transfer of specificity for human immunodeficiency virus type 1 into primary human T lymphocytes by introduction of T-cell receptor genes
LJN Cooper, M Kalos, DA Lewinsohn, SR Riddell, PD Greenberg
Journal of virology 74 (17), 8207-8212, 2000
Toward eliminating HLA class I expression to generate universal cells from allogeneic donors
H Torikai, A Reik, F Soldner, EH Warren, C Yuen, Y Zhou, DL Crossland, ...
Blood, The Journal of the American Society of Hematology 122 (8), 1341-1349, 2013
Phase 1 studies of central memory–derived CD19 CAR T–cell therapy following autologous HSCT in patients with B-cell NHL
X Wang, LL Popplewell, JR Wagner, A Naranjo, MS Blanchard, MR Mott, ...
Blood, The Journal of the American Society of Hematology 127 (24), 2980-2990, 2016
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