Napoleone Ferrara
Napoleone Ferrara
Distinguished Professor, Hildyard Endowed Chair in Eye Disease, UCSD Moores Cancer Center
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Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
H Hurwitz, L Fehrenbacher, W Novotny, T Cartwright, J Hainsworth, ...
New England journal of medicine 350 (23), 2335-2342, 2004
The biology of VEGF and its receptors
N Ferrara, HP Gerber, J LeCouter
Nature medicine 9 (6), 669-676, 2003
Vascular endothelial growth factor is a secreted angiogenic mitogen
DW Leung, G Cachianes, WJ Kuang, DV Goeddel, N Ferrara
The biology of vascular endothelial growth factor
N Ferrara, T Davis-Smyth
Endocrine reviews 18 (1), 4-25, 1997
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
KJ Kim, B Li, J Winer, M Armanini, N Gillett, HS Phillips, N Ferrara
Nature 362 (6423), 841-844, 1993
Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders
LP Aiello, RL Avery, PG Arrigg, BA Keyt, HD Jampel, ST Shah, ...
New England Journal of Medicine 331 (22), 1480-1487, 1994
Vascular endothelial growth factor: basic science and clinical progress
N Ferrara
Endocrine reviews 25 (4), 581-611, 2004
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
N Ferrara, K Carver-Moore, H Chen, M Dowd, L Lu, KS O'Shea, ...
Nature 380 (6573), 439-442, 1996
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
N Ferrara, WJ Henzel
Biochemical and biophysical research communications 161 (2), 851-858, 1989
Angiogenesis as a therapeutic target
N Ferrara, RS Kerbel
Nature 438 (7070), 967-974, 2005
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
N Ferrara, KJ Hillan, HP Gerber, W Novotny
Nature reviews Drug discovery 3 (5), 391-400, 2004
The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
C De Vries, JA Escobedo, H Ueno, K Houck, N Ferrara, LT Williams
Science 255 (5047), 989-991, 1992
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway: requirement for Flk-1/KDR …
HP Gerber, A McMurtrey, J Kowalski, M Yan, BA Keyt, V Dixit, N Ferrara
Journal of Biological Chemistry 273 (46), 30336-30343, 1998
VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
HP Gerber, TH Vu, AM Ryan, J Kowalski, Z Werb, N Ferrara
Nature medicine 5 (6), 623-628, 1999
HIF-1α is essential for myeloid cell-mediated inflammation
T Cramer, Y Yamanishi, BE Clausen, I Förster, R Pawlinski, N Mackman, ...
Cell 112 (5), 645-657, 2003
Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
LG Presta, H Chen, SJ O'Connor, V Chisholm, YG Meng, L Krummen, ...
Cancer research 57 (20), 4593-4599, 1997
Molecular and biological properties of the vascular endothelial growth factor family of proteins
N Ferrara, K Houck, LYN Jakeman, DW Leung
Endocrine reviews 13 (1), 18-32, 1992
VEGF and the quest for tumour angiogenesis factors
N Ferrara
Nature Reviews Cancer 2 (10), 795-803, 2002
The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA
KA Houck, N Ferrara, J Winer, G Cachianes, B Li, DW Leung
Molecular endocrinology 5 (12), 1806-1814, 1991
VEGF in signaling and disease: beyond discovery and development
RS Apte, DS Chen, N Ferrara
Cell 176 (6), 1248-1264, 2019
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