| A roadmap to success in photopharmacology J Broichhagen, JA Frank, D Trauner Accounts of chemical research 48 (7), 1947-1960, 2015 | 658 | 2015 |
| Beta cell hubs dictate pancreatic islet responses to glucose NR Johnston, RK Mitchell, E Haythorne, MP Pessoa, F Semplici, J Ferrer, ... Cell metabolism 24 (3), 389-401, 2016 | 433 | 2016 |
| Strain-promoted alkyne azide cycloaddition for the functionalization of poly (amide)-based dendrons and dendrimers C Ornelas, J Broichhagen, M Weck Journal of the American Chemical Society 132 (11), 3923-3931, 2010 | 165 | 2010 |
| Optical control of insulin release using a photoswitchable sulfonylurea J Broichhagen, M Schönberger, SC Cork, JA Frank, P Marchetti, ... Nature communications 5 (1), 5116, 2014 | 130 | 2014 |
| Orthogonal optical control of a G protein-coupled receptor with a SNAP-tethered photochromic ligand J Broichhagen, A Damijonaitis, J Levitz, KR Sokol, P Leippe, D Konrad, ... ACS central science 1 (7), 383-393, 2015 | 117 | 2015 |
| Optical control of insulin secretion using an incretin switch J Broichhagen, T Podewin, H Meyer‐Berg, Y Von Ohlen, NR Johnston, ... Angewandte Chemie International Edition 54 (51), 15565-15569, 2015 | 101 | 2015 |
| Optical control of acetylcholinesterase with a tacrine switch J Broichhagen, I Jurastow, K Iwan, W Kummer, D Trauner Angewandte Chemie International Edition 53 (29), 7657-7660, 2014 | 95 | 2014 |
| Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics J Ast, A Arvaniti, NHF Fine, D Nasteska, FB Ashford, Z Stamataki, ... Nature Communications 11 (1), 467, 2020 | 89 | 2020 |
| Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor MH Berry, A Holt, J Levitz, J Broichhagen, BM Gaub, M Visel, C Stanley, ... Nature communications 8 (1), 1862, 2017 | 80 | 2017 |
| Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors J Levitz, J Broichhagen, P Leippe, D Konrad, D Trauner, EY Isacoff Proceedings of the National Academy of Sciences 114 (17), E3546-E3554, 2017 | 72 | 2017 |
| The in vivo chemistry of photoswitched tethered ligands J Broichhagen, D Trauner Current opinion in chemical biology 21, 121-127, 2014 | 64 | 2014 |
| A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function J Broichhagen, JA Frank, NR Johnston, RK Mitchell, K Šmid, P Marchetti, ... Chemical Communications 51 (27), 6018-6021, 2015 | 59 | 2015 |
| Branched photoswitchable tethered ligands enable ultra-efficient optical control and detection of G protein-coupled receptors in vivo A Acosta-Ruiz, VA Gutzeit, MJ Skelly, S Meadows, J Lee, P Parekh, ... Neuron 105 (3), 446-463. e13, 2020 | 58 | 2020 |
| Genetically targeted optical control of an endogenous G protein-coupled receptor PC Donthamsetti, J Broichhagen, V Vyklicky, C Stanley, Z Fu, M Visel, ... Journal of the American Chemical Society 141 (29), 11522-11530, 2019 | 58 | 2019 |
| AzoCholine enables optical control of alpha 7 nicotinic acetylcholine receptors in neural networks A Damijonaitis, J Broichhagen, T Urushima, K Hüll, J Nagpal, L Laprell, ... ACS chemical neuroscience 6 (5), 701-707, 2015 | 56 | 2015 |
| Allosteric optical control of a class BG‐protein‐coupled receptor J Broichhagen, NR Johnston, Y Von Ohlen, H Meyer‐Berg, BJ Jones, ... Angewandte Chemie International Edition 55 (19), 5865-5868, 2016 | 47 | 2016 |
| SNAP-Tagged Nanobodies Enable Reversible Optical Control of a G Protein-Coupled Receptor via a Remotely Tethered Photoswitchable Ligand H Farrants, VA Gutzeit, A Acosta-Ruiz, D Trauner, K Johnsson, J Levitz, ... ACS chemical biology 13 (9), 2682-2688, 2018 | 46 | 2018 |
| Optical control of GPR40 signalling in pancreatic β-cells JA Frank, DA Yushchenko, NHF Fine, M Duca, M Citir, J Broichhagen, ... Chemical science 8 (11), 7604-7610, 2017 | 46 | 2017 |
| Remote control of glucose homeostasis in vivo using photopharmacology ZB Mehta, NR Johnston, MS Nguyen-Tu, J Broichhagen, P Schultz, ... Scientific reports 7 (1), 291, 2017 | 44 | 2017 |
| GLP1R attenuates sympathetic response to high glucose via carotid body inhibition AG Pauza, P Thakkar, T Tasic, I Felippe, P Bishop, MP Greenwood, ... Circulation research 130 (5), 694-707, 2022 | 40 | 2022 |
Dirk TraunerUniversity of PennsylvaniaVerified email at upenn.edu
