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Caspase 8 small interfering RNA prevents acute liver failure in mice L Zender, S Hütker, C Liedtke, HL Tillmann, S Zender, B Mundt, ... Proceedings of the National Academy of Sciences 100 (13), 7797-7802, 2003 | 522 | 2003 |
A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase NP Malek, H Sundberg, S McGrew, K Nakayama, TR Kyriakidis, ... Nature 413 (6853), 323-327, 2001 | 333 | 2001 |
In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer R Rudalska, D Dauch, T Longerich, K McJunkin, T Wuestefeld, TW Kang, ... Nature medicine 20 (10), 1138-1146, 2014 | 304 | 2014 |
A MYC–aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer D Dauch, R Rudalska, G Cossa, JC Nault, TW Kang, T Wuestefeld, ... Nature medicine 22 (7), 744-753, 2016 | 278 | 2016 |
A critical role for notch signaling in the formation of cholangiocellular carcinomas S Zender, I Nickeleit, T Wuestefeld, I Sörensen, D Dauch, P Bozko, ... Cancer cell 23 (6), 784-795, 2013 | 236 | 2013 |
Skp2-dependent degradation of p27kip1 is essential for cell cycle progression U Kossatz, N Dietrich, L Zender, J Buer, MP Manns, NP Malek Genes & development 18 (21), 2602-2607, 2004 | 225 | 2004 |
NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer C Heining, P Horak, S Uhrig, PL Codo, B Klink, B Hutter, M Fröhlich, ... Cancer discovery 8 (9), 1087-1095, 2018 | 218 | 2018 |
Argyrin A reveals a critical role for the tumor suppressor protein p27kip1 in mediating antitumor activities in response to proteasome inhibition I Nickeleit, S Zender, F Sasse, R Geffers, G Brandes, I Sörensen, ... Cancer cell 14 (1), 23-35, 2008 | 216 | 2008 |
Antibody-induced procoagulant platelets in severe COVID-19 infection K Althaus, I Marini, J Zlamal, L Pelzl, A Singh, H Häberle, M Mehrländer, ... Blood, The Journal of the American Society of Hematology 137 (8), 1061-1071, 2021 | 189 | 2021 |
The SCF–FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication A Puklowski, Y Homsi, D Keller, M May, S Chauhan, U Kossatz, ... Nature cell biology 13 (8), 1004-1009, 2011 | 181 | 2011 |
A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration T Wuestefeld, M Pesic, R Rudalska, D Dauch, T Longerich, TW Kang, ... Cell 153 (2), 389-401, 2013 | 166 | 2013 |
Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT AM Mirza, S Gysin, N Malek, K Nakayama, JM Roberts, M McMahon Molecular and cellular biology 24 (24), 10868-10881, 2004 | 165 | 2004 |
NF-κB determines between apoptosis and proliferation in hepatocytes during liver regeneration J Plümpe, NP Malek, CT Bock, T Rakemann, MP Manns, C Trautwein American Journal of Physiology-Gastrointestinal and Liver Physiology 278 (1 …, 2000 | 145 | 2000 |
The diagnosis and treatment of hepatocellular carcinoma NP Malek, S Schmidt, P Huber, MP Manns, TF Greten Deutsches Ärzteblatt International 111 (7), 101, 2014 | 144 | 2014 |
Resminostat plus sorafenib as second-line therapy of advanced hepatocellular carcinoma–the SHELTER study M Bitzer, M Horger, EG Giannini, TM Ganten, MA Wörns, JT Siveke, ... Journal of hepatology 65 (2), 280-288, 2016 | 130 | 2016 |
Diagnosis of and therapy for hepatocellular carcinoma TF Greten, NP Malek, S Schmidt, J Arends, P Bartenstein, W Bechstein, ... Zeitschrift fur Gastroenterologie 51 (11), 1269, 2013 | 129 | 2013 |
Delayed versus immediate treatment for patients with acute hepatitis C: a randomised controlled non-inferiority trial K Deterding, N Grüner, P Buggisch, J Wiegand, PR Galle, U Spengler, ... The Lancet infectious diseases 13 (6), 497-506, 2013 | 126 | 2013 |
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