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dr.nisar malik
dr.nisar malik
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NASH limits anti-tumour surveillance in immunotherapy-treated HCC
D Pfister, NG Núñez, R Pinyol, O Govaere, M Pinter, M Szydlowska, ...
Nature 592 (7854), 450-456, 2021
8052021
Caspase 8 small interfering RNA prevents acute liver failure in mice
L Zender, S Hütker, C Liedtke, HL Tillmann, S Zender, B Mundt, ...
Proceedings of the National Academy of Sciences 100 (13), 7797-7802, 2003
5222003
A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase
NP Malek, H Sundberg, S McGrew, K Nakayama, TR Kyriakidis, ...
Nature 413 (6853), 323-327, 2001
3332001
In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer
R Rudalska, D Dauch, T Longerich, K McJunkin, T Wuestefeld, TW Kang, ...
Nature medicine 20 (10), 1138-1146, 2014
3042014
A MYC–aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer
D Dauch, R Rudalska, G Cossa, JC Nault, TW Kang, T Wuestefeld, ...
Nature medicine 22 (7), 744-753, 2016
2782016
A critical role for notch signaling in the formation of cholangiocellular carcinomas
S Zender, I Nickeleit, T Wuestefeld, I Sörensen, D Dauch, P Bozko, ...
Cancer cell 23 (6), 784-795, 2013
2362013
Skp2-dependent degradation of p27kip1 is essential for cell cycle progression
U Kossatz, N Dietrich, L Zender, J Buer, MP Manns, NP Malek
Genes & development 18 (21), 2602-2607, 2004
2252004
NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer
C Heining, P Horak, S Uhrig, PL Codo, B Klink, B Hutter, M Fröhlich, ...
Cancer discovery 8 (9), 1087-1095, 2018
2182018
Argyrin A reveals a critical role for the tumor suppressor protein p27kip1 in mediating antitumor activities in response to proteasome inhibition
I Nickeleit, S Zender, F Sasse, R Geffers, G Brandes, I Sörensen, ...
Cancer cell 14 (1), 23-35, 2008
2162008
Antibody-induced procoagulant platelets in severe COVID-19 infection
K Althaus, I Marini, J Zlamal, L Pelzl, A Singh, H Häberle, M Mehrländer, ...
Blood, The Journal of the American Society of Hematology 137 (8), 1061-1071, 2021
1892021
The SCF–FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication
A Puklowski, Y Homsi, D Keller, M May, S Chauhan, U Kossatz, ...
Nature cell biology 13 (8), 1004-1009, 2011
1812011
A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration
T Wuestefeld, M Pesic, R Rudalska, D Dauch, T Longerich, TW Kang, ...
Cell 153 (2), 389-401, 2013
1662013
Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT
AM Mirza, S Gysin, N Malek, K Nakayama, JM Roberts, M McMahon
Molecular and cellular biology 24 (24), 10868-10881, 2004
1652004
NF-κB determines between apoptosis and proliferation in hepatocytes during liver regeneration
J Plümpe, NP Malek, CT Bock, T Rakemann, MP Manns, C Trautwein
American Journal of Physiology-Gastrointestinal and Liver Physiology 278 (1 …, 2000
1452000
The diagnosis and treatment of hepatocellular carcinoma
NP Malek, S Schmidt, P Huber, MP Manns, TF Greten
Deutsches Ärzteblatt International 111 (7), 101, 2014
1442014
Resminostat plus sorafenib as second-line therapy of advanced hepatocellular carcinoma–the SHELTER study
M Bitzer, M Horger, EG Giannini, TM Ganten, MA Wörns, JT Siveke, ...
Journal of hepatology 65 (2), 280-288, 2016
1302016
Diagnosis of and therapy for hepatocellular carcinoma
TF Greten, NP Malek, S Schmidt, J Arends, P Bartenstein, W Bechstein, ...
Zeitschrift fur Gastroenterologie 51 (11), 1269, 2013
1292013
Delayed versus immediate treatment for patients with acute hepatitis C: a randomised controlled non-inferiority trial
K Deterding, N Grüner, P Buggisch, J Wiegand, PR Galle, U Spengler, ...
The Lancet infectious diseases 13 (6), 497-506, 2013
1262013
The cellular level of telomere dysfunction determines induction of senescence or apoptosis in vivo
A Lechel, A Satyanarayana, Z Ju, RR Plentz, S Schaetzlein, C Rudolph, ...
EMBO reports 6 (3), 275-281, 2005
1242005
Epidemiological trends in incidence and mortality of hepatobiliary cancers in Germany
T Von Hahn, S Ciesek, G Wegener, RR Plentz, TJ Weismüller, ...
Scandinavian journal of gastroenterology 46 (9), 1092-1098, 2011
1232011
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