SGLT2 inhibition by empagliflozin promotes fat utilization and browning and attenuates inflammation and insulin resistance by polarizing M2 macrophages in diet-induced obese mice L Xu, N Nagata, M Nagashimada, F Zhuge, Y Ni, G Chen, E Mayoux, ... EBioMedicine 20, 137-149, 2017 | 441 | 2017 |
Roles of chemokines and chemokine receptors in obesity-associated insulin resistance and nonalcoholic fatty liver disease L Xu, H Kitade, Y Ni, T Ota Biomolecules 5 (3), 1563-1579, 2015 | 228 | 2015 |
DPP-4 inhibition by linagliptin attenuates obesity-related inflammation and insulin resistance by regulating M1/M2 macrophage polarization F Zhuge, Y Ni, M Nagashimada, N Nagata, L Xu, N Mukaida, S Kaneko, ... Diabetes 65 (10), 2966-2979, 2016 | 201 | 2016 |
Glucoraphanin ameliorates obesity and insulin resistance through adipose tissue browning and reduction of metabolic endotoxemia in mice N Nagata, L Xu, S Kohno, Y Ushida, Y Aoki, R Umeda, N Fuke, F Zhuge, ... Diabetes 66 (5), 1222-1236, 2017 | 157 | 2017 |
Emerging roles of SGLT2 inhibitors in obesity and insulin resistance: Focus on fat browning and macrophage polarization L Xu, T Ota Adipocyte 7 (2), 121-128, 2017 | 128 | 2017 |
Empagliflozin reverses obesity and insulin resistance through fat browning and alternative macrophage activation in mice fed a high-fat diet L Xu, N Nagata, G Chen, M Nagashimada, F Zhuge, Y Ni, Y Sakai, ... BMJ Open Diabetes Research and Care 7 (1), e000783, 2019 | 95 | 2019 |
Adipose tissue macrophage phenotypes and characteristics: the key to insulin resistance in obesity and metabolic disorders Y Ni, L Ni, F Zhuge, L Xu, Z Fu, T Ota Obesity 28 (2), 225-234, 2020 | 88 | 2020 |
Micronutrient antioxidants and nonalcoholic fatty liver disease G Chen, Y Ni, N Nagata, L Xu, T Ota International journal of molecular sciences 17 (9), 1379, 2016 | 87 | 2016 |
Glucoraphanin: a broccoli sprout extract that ameliorates obesity-induced inflammation and insulin resistance L Xu, N Nagata, T Ota Adipocyte 7 (3), 218-225, 2018 | 83 | 2018 |
Lycopene prevents the progression of lipotoxicity-induced nonalcoholic steatohepatitis by decreasing oxidative stress in mice Y Ni, F Zhuge, M Nagashimada, N Nagata, L Xu, S Yamamoto, N Fuke, ... Free Radical Biology and Medicine 152, 571-582, 2020 | 61 | 2020 |
Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice T Nishikawa, N Nagata, T Shimakami, T Shirakura, C Matsui, Y Ni, ... Scientific reports 10 (1), 815, 2020 | 60 | 2020 |
Lycopene alleviates obesity‐induced inflammation and insulin resistance by regulating M1/M2 status of macrophages G Chen, Y Ni, N Nagata, F Zhuge, L Xu, M Nagashimada, S Yamamoto, ... Molecular nutrition & food research 63 (21), 1900602, 2019 | 56 | 2019 |
Impact of glucoraphanin-mediated activation of Nrf2 on non-alcoholic fatty liver disease with a focus on mitochondrial dysfunction L Xu, N Nagata, T Ota International journal of molecular sciences 20 (23), 5920, 2019 | 51 | 2019 |
CC chemokine ligand 3 deficiency ameliorates diet-induced steatohepatitis by regulating liver macrophage recruitment and M1/M2 status in mice L Xu, Y Chen, M Nagashimada, Y Ni, F Zhuge, G Chen, H Li, T Pan, ... Metabolism 125, 154914, 2021 | 48 | 2021 |
β‐Cryptoxanthin exerts greater cardioprotective effects on cardiac ischemia‐reperfusion injury than astaxanthin by attenuating mitochondrial dysfunction in mice W Pongkan, O Takatori, Y Ni, L Xu, N Nagata, SC Chattipakorn, S Usui, ... Molecular nutrition & food research 61 (10), 1601077, 2017 | 37 | 2017 |
CX3CL1–CX3CR1 signalling deficiency exacerbates obesity-induced inflammation and insulin resistance in male mice M Nagashimada, K Sawamoto, Y Ni, H Kitade, N Nagata, L Xu, M Kobori, ... Endocrinology, 2021 | 28 | 2021 |
Pirfenidone prevents and reverses hepatic insulin resistance and steatohepatitis by polarizing M2 macrophages G Chen, Y Ni, N Nagata, L Xu, F Zhuge, M Nagashimada, S Kaneko, ... Laboratory Investigation 99 (9), 1335-1348, 2019 | 25 | 2019 |
Swertiamarin supplementation prevents obesity-related chronic inflammation and insulin resistance in mice fed a high-fat diet L Xu, D Li, Y Zhu, S Cai, X Liang, Y Tang, S Jin, C Ding Adipocyte 10 (1), 160-173, 2021 | 23 | 2021 |
Suppression of obesity by melatonin through increasing energy expenditure and accelerating lipolysis in mice fed a high-fat diet L Xu, D Li, H Li, O Zhang, Y Huang, H Shao, Y Wang, S Cai, Y Zhu, S Jin, ... Nutrition & Diabetes 12 (1), 42, 2022 | 22 | 2022 |
An update on the chemokine system in the development of NAFLD N Nagata, G Chen, L Xu, H Ando Medicina 58 (6), 761, 2022 | 22 | 2022 |