| Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency J Frew, A Baradaran-Heravi, AD Balgi, X Wu, TD Yan, S Arns, ... Molecular neurodegeneration 15, 1-19, 2020 | 22 | 2020 |
| Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice J Frew, HB Nygaard Acta Neuropathologica Communications 9 (1), 57, 2021 | 11 | 2021 |
| Simultaneous imaging of redox states in dystrophic neurites and microglia at Aβ plaques indicate lysosome accumulation not microglia correlate with increased oxidative stress S Wendt, S Johnson, NL Weilinger, C Groten, S Sorrentino, J Frew, ... Redox Biology 56, 102448, 2022 | 4 | 2022 |
| Generation of an induced pluripotent stem cell line (UBCi001-a) from a presymptomatic individual carrying the R418X progranulin gene mutation J Frew, X Wu, GY Hsiung, HH Feldman, IR Mackenzie, HB Nygaard Stem Cell Research 41, 101582, 2019 | 2 | 2019 |
| Premature termination codon readthrough restores progranulin expression in preclinical models of frontotemporal dementia and neuronal ceroid lipofuscinosis J Frew University of British Columbia, 2021 | 1 | 2021 |
| hiPSC-derived GRN-deficient astrocytes delay spiking activity of developing neurons C Lee, J Frew, NL Weilinger, S Wendt, W Cai, S Sorrentino, X Wu, ... Neurobiology of Disease 181, 106124, 2023 | | 2023 |
| INTRANEURONAL CA (2+) SIGNALING IN INDUCED PLURIPOTENT STEM CELLS FROM DRAVET SYNDROME PATIENTS N Fameli, J Frew, C van Breemen, M Connolly, H Nygaard, G Horvath MOLECULAR GENETICS AND METABOLISM 127 (3), 267-267, 2019 | | 2019 |
| A paradigm shift: does herpes simplex virus type 1 play a causal role in the progression of late-onset Alzheimer’s disease? JEMI-PEARLS. 1: 1-20 J Frew December 1, 2, 2015 | | 2015 |
