| Genomic instability and aging-like phenotype in the absence of mammalian SIRT6 R Mostoslavsky, KF Chua, DB Lombard, WW Pang, MR Fischer, L Gellon, ... Cell 124 (2), 315-329, 2006 | 1836 | 2006 |
| SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation MD Hirschey, T Shimazu, E Goetzman, E Jing, B Schwer, DB Lombard, ... Nature 464 (7285), 121-125, 2010 | 1733 | 2010 |
| A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy IH Lee, L Cao, R Mostoslavsky, DB Lombard, J Liu, NE Bruns, M Tsokos, ... Proceedings of the National Academy of Sciences 105 (9), 3374-3379, 2008 | 1559 | 2008 |
| Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation DB Lombard, FW Alt, HL Cheng, J Bunkenborg, RS Streeper, ... Molecular and cellular biology 27 (24), 8807-8814, 2007 | 1384 | 2007 |
| DNA repair, genome stability, and aging DB Lombard, KF Chua, R Mostoslavsky, S Franco, M Gostissa, FW Alt Cell 120 (4), 497-512, 2005 | 1085 | 2005 |
| SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways J Park, Y Chen, DX Tishkoff, C Peng, M Tan, L Dai, Z Xie, Y Zhang, ... Molecular cell 50 (6), 919-930, 2013 | 902 | 2013 |
| The first identification of lysine malonylation substrates and its regulatory enzyme C Peng, Z Lu, Z Xie, Z Cheng, Y Chen, M Tan, H Luo, Y Zhang, W He, ... Molecular & cellular proteomics 10 (12), 2011 | 754 | 2011 |
| Lysine glutarylation is a protein posttranslational modification regulated by SIRT5 M Tan, C Peng, KA Anderson, P Chhoy, Z Xie, L Dai, J Park, Y Chen, ... Cell metabolism 19 (4), 605-617, 2014 | 750 | 2014 |
| The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism C Sebastián, BMM Zwaans, DM Silberman, M Gymrek, A Goren, L Zhong, ... Cell 151 (6), 1185-1199, 2012 | 695 | 2012 |
| Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally Y Zhang, SH Kwon, T Yamaguchi, F Cubizolles, S Rousseaux, M Kneissel, ... Molecular and cellular biology 28 (5), 1688-1701, 2008 | 641 | 2008 |
| Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production E Jing, B Emanuelli, MD Hirschey, J Boucher, KY Lee, D Lombard, ... Proceedings of the national academy of sciences 108 (35), 14608-14613, 2011 | 537 | 2011 |
| Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7. GJ Freeman, GS Gray, CD Gimmi, DB Lombard, LJ Zhou, M White, ... The Journal of experimental medicine 174 (3), 625-631, 1991 | 536 | 1991 |
| Essential role of limiting telomeres in the pathogenesis of Werner syndrome S Chang, AS Multani, NG Cabrera, ML Naylor, P Laud, D Lombard, ... Nature genetics 36 (8), 877-882, 2004 | 522 | 2004 |
| SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production T Shimazu, MD Hirschey, L Hua, KE Dittenhafer-Reed, B Schwer, ... Cell metabolism 12 (6), 654-661, 2010 | 521 | 2010 |
| Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice GJ Freeman, F Borriello, RJ Hodes, H Reiser, KS Hathcock, G Laszlo, ... Science 262 (5135), 907-909, 1993 | 519 | 1993 |
| Characterization of CTLA-4 structure and expression on human T cells. T Lindsten, KP Lee, ES Harris, B Petryniak, N Craighead, PJ Reynolds, ... Journal of immunology (Baltimore, Md.: 1950) 151 (7), 3489-3499, 1993 | 471 | 1993 |
| Metabolic regulation of gene expression by histone lysine β-hydroxybutyrylation Z Xie, D Zhang, D Chung, Z Tang, H Huang, L Dai, S Qi, J Li, G Colak, ... Molecular cell 62 (2), 194-206, 2016 | 470 | 2016 |
| The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun NR Sundaresan, P Vasudevan, L Zhong, G Kim, S Samant, V Parekh, ... Nature medicine 18 (11), 1643-1650, 2012 | 467 | 2012 |
| Leaky Scid phenotype associated with defective V (D) J coding end processing in Artemis-deficient mice S Rooney, JA Sekiguchi, C Zhu, HL Cheng, J Manis, S Whitlow, J DeVido, ... Molecular cell 10 (6), 1379-1390, 2002 | 328 | 2002 |
| H2AX prevents DNA breaks from progressing to chromosome breaks and translocations S Franco, M Gostissa, S Zha, DB Lombard, MM Murphy, AA Zarrin, C Yan, ... Molecular cell 21 (2), 201-214, 2006 | 312 | 2006 |
