Improved virus purification processes for vaccines and gene therapy P Nestola, C Peixoto, RRJS Silva, PM Alves, JPB Mota, MJT Carrondo Biotechnology and bioengineering 112 (5), 843-857, 2015 | 139 | 2015 |
Current challenges in biotherapeutic particles manufacturing MG Moleirinho, RJS Silva, PM Alves, MJT Carrondo, C Peixoto Expert opinion on biological therapy 20 (5), 451-465, 2020 | 102 | 2020 |
Adenovirus purification by two-column, size-exclusion, simulated countercurrent chromatography P Nestola, RJS Silva, C Peixoto, PM Alves, MJT Carrondo, JPB Mota Journal of Chromatography A 1347, 111-121, 2014 | 63 | 2014 |
Exploring continuous and integrated strategies for the up-and downstream processing of human mesenchymal stem cells B Cunha, T Aguiar, MM Silva, RJS Silva, MFQ Sousa, E Pineda, C Peixoto, ... Journal of biotechnology 213, 97-108, 2015 | 62 | 2015 |
Membrane‐based approach for the downstream processing of influenza virus‐like particles SB Carvalho, RJS Silva, MG Moleirinho, B Cunha, AS Moreira, ... Biotechnology journal 14 (8), 1800570, 2019 | 43 | 2019 |
Robust design of adenovirus purification by two-column, simulated moving-bed, size-exclusion chromatography P Nestola, RJS Silva, C Peixoto, PM Alves, MJT Carrondo, JPB Mota Journal of Biotechnology 213, 109-119, 2015 | 40 | 2015 |
A new multicolumn, open-loop process for center-cut separation by solvent-gradient chromatography RJS Silva, RCR Rodrigues, H Osuna-Sanchez, M Bailly, E Valéry, ... Journal of Chromatography A 1217 (52), 8257-8269, 2010 | 37 | 2010 |
Clinical-grade oncolytic adenovirus purification using polysorbate 20 as an alternative for cell lysis MG Moleirinho, S Rosa, MJT Carrondo, RJS Silva, Å Hagner-McWhirter, ... Current gene therapy 18 (6), 366-374, 2018 | 31 | 2018 |
Exosome-based therapeutics: Purification using semi-continuous multi-column chromatography MG Moleirinho, RJS Silva, MJT Carrondo, PM Alves, C Peixoto Separation and Purification Technology 224, 515-523, 2019 | 30 | 2019 |
Streamlined, two-column, simulated countercurrent chromatography for binary separation RCR Rodrigues, RJS Silva, JPB Mota Journal of Chromatography A 1217 (20), 3382-3391, 2010 | 30 | 2010 |
3D-printed ordered bed structures for chromatographic purification of enveloped and non-enveloped viral particles MG Moleirinho, S Feast, AS Moreira, RJS Silva, PM Alves, MJT Carrondo, ... Separation and Purification Technology 254, 117681, 2021 | 29 | 2021 |
Efficient filtration strategies for the clarification of influenza virus-like particles derived from insect cells SB Carvalho, RJS Silva, AS Moreira, B Cunha, JJ Clemente, PM Alves, ... Separation and Purification Technology 218, 81-88, 2019 | 27 | 2019 |
Relay simulated moving bed chromatography: Concept and design criteria RJS Silva, RCR Rodrigues, JPB Mota Journal of Chromatography A 1260, 132-142, 2012 | 22 | 2012 |
Improving the downstream processing of vaccine and gene therapy vectors with continuous chromatography RJS Silva, JPB Mota, C Peixoto, PM Alves, MJT Carrondo Pharmaceutical Bioprocessing 3 (8), 489-505, 2015 | 21 | 2015 |
Development, construction, and operation of a multisample volumetric apparatus for the study of gas adsorption equilibrium RPPL Ribeiro, RJS Silva, IAAC Esteves, JPB Mota Journal of Chemical Education 92 (4), 757-761, 2015 | 20 | 2015 |
Improving washing strategies of human mesenchymal stem cells using negative mode expanded bed chromatography B Cunha, RJS Silva, T Aguiar, M Serra, J Daicic, JL Maloisel, J Clachan, ... Journal of Chromatography A 1429, 292-303, 2016 | 19 | 2016 |
Single-column simulated moving-bed process with recycle lag: analysis and applications JMM Araújo, RCR Rodrigues, RJS Silva, JPB Mota Adsorption Science & Technology 25 (9), 647-659, 2007 | 18 | 2007 |
Downstream processing for influenza vaccines and candidates: An update S B. Carvalho, C Peixoto, MJ T. Carrondo, RJ S. Silva Biotechnology and Bioengineering 118 (8), 2845-2869, 2021 | 16 | 2021 |
Baculovirus affinity removal in viral-based bioprocesses MG Moleirinho, RP Fernandes, SB Carvalho, S Bezemer, F Detmers, ... Separation and Purification Technology 241, 116693, 2020 | 13 | 2020 |
AAV process intensification by perfusion bioreaction and integrated clarification JP Mendes, B Fernandes, E Pineda, S Kudugunti, M Bransby, R Gantier, ... Frontiers in Bioengineering and Biotechnology 10, 1020174, 2022 | 12 | 2022 |