Palmitoleic acid reduces high fat diet-induced liver inflammation by promoting PPAR-γ-independent M2a polarization of myeloid cells CO Souza, AAS Teixeira, LA Biondo, LS Silveira, CN de Souza Breda, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2020 | 40 | 2020 |
Rational design of suprastat: a novel selective histone deacetylase 6 inhibitor with the ability to potentiate immunotherapy in melanoma models S Noonepalle, S Shen, J Ptáček, MT Tavares, G Zhang, J Stránský, ... Journal of Medicinal Chemistry 63 (18), 10246-10262, 2020 | 35 | 2020 |
The anti-inflammatory and immunomodulatory potential of braylin: Pharmacological properties and mechanisms by in silico, in vitro and in vivo approaches RF Espirito-Santo, CS Meira, RS Costa, OP Souza Filho, AF Evangelista, ... PLoS One 12 (6), e0179174, 2017 | 26 | 2017 |
Genomics, epigenomics and pharmacogenomics of familial hypercholesterolemia (FHBGEP): A study protocol JB Borges, VF de Oliveira, GM Ferreira, B Los, TKAA Barbosa, ... Research in social and administrative pharmacy 17 (7), 1347-1355, 2021 | 23 | 2021 |
Fragment‐based drug discovery as alternative strategy to the drug development for neglected diseases JFR Mello, RA Gomes, DG Vital‐Fujii, GM Ferreira, GHG Trossini Chemical biology & drug design 90 (6), 1067-1078, 2017 | 21 | 2017 |
Identification, in vitro testing and molecular docking studies of microginins’ mechanism of angiotensin-converting enzyme inhibition FCR Paiva, GM Ferreira, GHG Trossini, E Pinto Molecules 22 (12), 1884, 2017 | 18 | 2017 |
SARS-COV-2 Mpro conformational changes induced by covalently bound ligands GM Ferreira, T Kronenberger, AK Tonduru, RDC Hirata, MH Hirata, ... Journal of Biomolecular Structure and Dynamics 40 (22), 12347-12357, 2022 | 16 | 2022 |
Antiophidic activity of the secondary metabolite lupeol isolated from Zanthoxylum monogynum BM Dos Santos, GM Ferreira, MT Tavares, JC De Bona, MH Hirata, ... Toxicon 193, 38-47, 2021 | 12 | 2021 |
Inhibition of porcine aminopeptidase M (pAMP) by the pentapeptide microginins GM Ferreira, T Kronenberger, ÉC de Almeida, J Sampaio, CF Terra, ... Molecules 24 (23), 4369, 2019 | 12 | 2019 |
Synthesis, leishmanicidal activity, structural descriptors and structure–activity relationship of quinoline derivatives EJG Silva, A Bezerra-Souza, LFD Passero, MD Laurenti, GM Ferreira, ... Future Medicinal Chemistry 10 (17), 2069-2085, 2018 | 12 | 2018 |
Late response to rosuvastatin and statin-related myalgia due to SLCO1B1, SLCO1B3, ABCB11, and CYP3A5 variants in a patient with Familial Hypercholesterolemia: a case report C Dagli-Hernandez, RCC de Freitas, ESR Marçal, RM Gonçalves, ... Annals of Translational Medicine 9 (1), 2021 | 11 | 2021 |
Association of variants in MYH7, MYBPC3 and TNNT2 with sudden cardiac death-related risk factors in Brazilian patients with hypertrophic cardiomyopathy AA Mori, LR de Castro, RH Bortolin, GM Bastos, VF de Oliveira, ... Forensic Science International: Genetics 52, 102478, 2021 | 10 | 2021 |
Structure-activity relationship and mechanistic studies for a series of cinnamyl hydroxamate histone deacetylase inhibitors MT Tavares, LC de Almeida, T Kronenberger, GM Ferreira, TF de Divitiis, ... Bioorganic & Medicinal Chemistry 35, 116085, 2021 | 10 | 2021 |
Design, synthesis and biological activity of novel substituted 3-benzoic acid derivatives as MtDHFR inhibitors T Kronenberger, GM Ferreira, ADF de Souza, S da Silva Santos, A Poso, ... Bioorganic & Medicinal Chemistry 28 (15), 115600, 2020 | 10 | 2020 |
Turnover and Inactivation Mechanisms for (S)-3-Amino-4,4-difluorocyclopent-1-enecarboxylic Acid, a Selective Mechanism-Based Inactivator of Human Ornithine … S Shen, A Butrin, PF Doubleday, RD Melani, BA Beaupre, MT Tavares, ... Journal of the American Chemical Society 143 (23), 8689-8703, 2021 | 9 | 2021 |
LDLR missense variants disturb structural conformation and LDLR activity in T-lymphocytes of familial hypercholesterolemia patients TKA Barbosa, RDC Hirata, GM Ferreira, JB Borges, VF de Oliveira, ... Gene 853, 147084, 2023 | 8 | 2023 |
Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation … W Zhu, A Butrin, RD Melani, PF Doubleday, GM Ferreira, MT Tavares, ... Journal of the American Chemical Society 144 (12), 5629-5642, 2022 | 7 | 2022 |
Inhibitor induced conformational changes in SARS-COV-2 papain-like protease GM Ferreira, T Pillaiyar, MH Hirata, A Poso, T Kronenberger Scientific Reports 12 (1), 11585, 2022 | 6 | 2022 |
Isohemigossypolone: Antiophidic properties of a naphthoquinone isolated from Pachira aquatica Aubl. SAPB Vieira, BM Dos Santos, CDS Júnior, VF de Paula, MSR Gomes, ... Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2021 | 6 | 2021 |
QSAR studies on the human sirtuin 2 inhibition by non-covalent 7, 5, 2-anilinobenzamide derivatives GM Ferreira, JG de Magalhães, VG Maltarollo, T Kronenberger, ... Journal of Biomolecular Structure and Dynamics, 2019 | 6 | 2019 |