PPARγ-p53-mediated vasculoregenerative program to reverse pulmonary hypertension JK Hennigs, A Cao, CG Li, M Shi, J Mienert, K Miyagawa, J Körbelin, ... Circulation research 128 (3), 401-418, 2021 | 43 | 2021 |
BMPR 2 gene therapy for PAH acts via S mad and non‐S mad signalling RL Harper, AM Reynolds, CS Bonder, PN Reynolds Respirology 21 (4), 727-733, 2016 | 42 | 2016 |
BMPR 2 gene delivery reduces mutation‐related PAH and counteracts TGF‐β‐mediated pulmonary cell signalling F Feng, RL Harper, PN Reynolds Respirology 21 (3), 526-532, 2016 | 36 | 2016 |
BMPR2‐expressing bone marrow‐derived endothelial‐like progenitor cells alleviate pulmonary arterial hypertension in vivo RL Harper, S Maiolo, RJ Ward, J Seyfang, MP Cockshell, CS Bonder, ... Respirology 24 (11), 1095-1103, 2019 | 33 | 2019 |
Role of endothelial cells in pulmonary fibrosis via SREBP2 activation M Martin, J Zhang, Y Miao, M He, J Kang, HY Huang, CH Chou, ... JCI insight 6 (22), 2021 | 27 | 2021 |
Monocyte-released HERV-K dUTPase engages TLR4 and MCAM causing endothelial mesenchymal transition S Otsuki, T Saito, S Taylor, D Li, JR Moonen, DP Marciano, RL Harper, ... JCI insight 6 (15), 2021 | 22 | 2021 |
iPSC–endothelial cell phenotypic drug screening and in silico analyses identify tyrphostin-AG1296 for pulmonary arterial hypertension M Gu, M Donato, M Guo, N Wary, Y Miao, S Mao, T Saito, S Otsuki, ... Science translational medicine 13 (592), eaba6480, 2021 | 21 | 2021 |
Dysregulated smooth muscle cell BMPR2–ARRB2 axis causes pulmonary hypertension L Wang, JR Moonen, A Cao, S Isobe, CG Li, NF Tojais, S Taylor, ... Circulation Research 132 (5), 545-564, 2023 | 9 | 2023 |
Dysregulated zinc and sphingosine‐1‐phosphate signaling in pulmonary hypertension: Potential effects by targeting of bone morphogenetic protein receptor type 2 in pulmonary … HB Tran, S Maiolo, R Harper, PD Zalewski, PN Reynolds, S Hodge Cell Biology International 45 (11), 2368-2379, 2021 | 8 | 2021 |
Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome AA de Jesus, G Chen, D Yang, T Brdicka, NM Ruth, D Bennin, ... Nature Communications 14 (1), 1502, 2023 | 7 | 2023 |
Development of vascular disease models to explore disease causation and pathomechanisms of rare vascular diseases RL Harper, EA Ferrante, M Boehm Seminars in immunopathology 44 (3), 259-268, 2022 | 5 | 2022 |
Reduced FOXF1 links unrepaired DNA damage to pulmonary arterial hypertension S Isobe, RV Nair, HY Kang, L Wang, JR Moonen, T Shinohara, A Cao, ... Nature Communications 14 (1), 7578, 2023 | 3 | 2023 |
Mast cell activation and degranulation in acute artery injury: A target for post‐operative therapy RL Harper, F Fang, H San, A Negro, C St. Hilaire, D Yang, G Chen, Z Yu, ... The FASEB Journal 37 (7), e23029, 2023 | 3 | 2023 |
Characteristics and utility of exosomes obtained from peripheral blood derived endothelial progenitor cells of PAH patients R Harper, M Cockshell, C Bonder, P Reynolds European Respiratory Journal 50 (suppl 61), 2017 | 1 | 2017 |
Culture of PAH peripheral blood derived endothelial progenitor cells allows isolation of exosomes and analysis of their surface markers R Harper, M Cockshell, CS Bonder, PN Reynolds A28. EXOSOMES AND MICRORNA, A1221-A1221, 2017 | 1 | 2017 |
Derived myeloid lineage induced pluripotent stem as a platform to study human CC chemokine receptor type 5Δ32 homozygotes G Chen, F Calcaterra, Y Ma, X Ping, E Pontarini, D Yang, F Oriolo, Z Yu, ... Iscience 26 (11), 2023 | | 2023 |
Human induced pluripotent stem cells generated from a patient with a homozygous mutation in the Lyn kinase gene (vol 64, 102933, 2022) R Harper, Q Yu, Y Liu, D Yang, J Zou, J Beers, AA Rasheed, ... STEM CELL RESEARCH 69, 2023 | | 2023 |
Corrigendum to" Human induced pluripotent stem cells generated from a patient with a homozygous mutation in the Lyn kinase gene"[Stem Cell Res. 64 (2022) 102933] R Harper, Q Yu, Y Liu, D Yang, J Zou, J Beers, AA de Jesus Rasheed, ... Stem cell research 69, 103059, 2023 | | 2023 |
Human induced pluripotent stem cells generated from a patient with a homozygous mutation in the Lyn kinase gene R Harper, Q Yu, Y Liu, D Yang, J Zou, J Beers, AA de Jesus Rasheed, ... Stem cell research 64, 102933, 2022 | | 2022 |
Gain-of-Function Mutations in Lyn Kinase Cause a Novel Autoinflammatory Disease with Small Vessel Vasculitis and Liver Fibrosis AA de Jesus, G Chen, D Yang, T Brdicka, N Ruth, D Bennin, ... ARTHRITIS & RHEUMATOLOGY 74, 1150-1151, 2022 | | 2022 |