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Lizhe Zhu
Lizhe Zhu
Assistant Professor @ The Chinese University of Hong Kong (Shenzhen)
在 cuhk.edu.cn 的电子邮件经过验证
标题
引用次数
引用次数
年份
miRTarBase update 2022: an informative resource for experimentally validated miRNA–target interactions
HY Huang, YCD Lin, S Cui, Y Huang, Y Tang, J Xu, J Bao, Y Li, J Wen, ...
Nucleic acids research 50 (D1), D222-D230, 2022
3372022
Constructing Markov State Models to elucidate the functional conformational changes of complex biomolecules
W Wang, S Cao, L Zhu, X Huang
Wiley Interdisciplinary Reviews: Computational Molecular Science 6, e1343, 2017
1362017
Unraveling the aggregation effect on amorphous phase AIE luminogens: a computational study
X Zheng, Q Peng, L Zhu, Y Xie, X Huang, Z Shuai
Nanoscale 8 (33), 15173-15180, 2016
1172016
Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes
P Xiao, W Yan, L Gou, YN Zhong, L Kong, C Wu, X Wen, Y Yuan, S Cao, ...
Cell 184 (4), 943-956. e18, 2021
902021
A deep learning framework to predict binding preference of RNA constituents on protein surface
JH Lam, Y Li, L Zhu, R Umarov, H Jiang, A Héliou, FK Sheong, T Liu, ...
Nature communications 10 (1), 4941, 2019
832019
Markov state models reveal a two-step mechanism of miRNA loading into the human argonaute protein: selective binding followed by structural re-arrangement
H Jiang, FK Sheong, L Zhu, X Gao, J Bernauer, X Huang
PLoS computational biology 11 (7), e1004404, 2015
612015
dbAMP 2.0: updated resource for antimicrobial peptides with an enhanced scanning method for genomic and proteomic data
JH Jhong, L Yao, Y Pang, Z Li, CR Chung, R Wang, S Li, W Li, M Luo, ...
Nucleic acids research 50 (D1), D460-D470, 2022
552022
Discovery of an orally active VHL-recruiting PROTAC that achieves robust HMGCR degradation and potent hypolipidemic activity in vivo
G Luo, Z Li, X Lin, X Li, Y Chen, K Xi, M Xiao, H Wei, L Zhu, H Xiang
Acta Pharmaceutica Sinica B 11 (5), 1300-1314, 2021
532021
Adaptive partitioning by local densitypeaks: An efficient densitybased clustering algorithm for analyzing molecular dynamics trajectories
S Liu, L Zhu, FK Sheong, W Wang, X Huang
Journal of Computational Chemistry 38 (3), 152-160, 2017
412017
Molecular mechanisms of RNA polymerase II transcription elongation elucidated by kinetic network models
IC Unarta, L Zhu, CKM Tse, PPH Cheung, J Yu, X Huang
Current Opinion in Structural Biology 49, 54-62, 2018
292018
Single-molecule investigations of conformation adaptation of porphyrins on surfaces
Q Zhang, X Zheng, G Kuang, W Wang, L Zhu, R Pang, X Shi, X Shang, ...
The Journal of Physical Chemistry Letters 8 (6), 1241-1247, 2017
292017
Kinetics-controlled amphiphile self-assembly processes
X Zheng, L Zhu, X Zeng, L Meng, L Zhang, D Wang, X Huang
The journal of physical chemistry letters 8 (8), 1798-1803, 2017
272017
Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism
Y Han, Q Zhuang, B Sun, W Lv, S Wang, Q Xiao, B Pang, Y Zhou, F Wang, ...
Nature Communications 12 (1), 449, 2021
252021
Structural insights into sphingosine-1-phosphate receptor activation
L Yu, L He, B Gan, R Ti, Q Xiao, X Yang, H Hu, L Zhu, S Wang, R Ren
Proceedings of the National Academy of Sciences 119 (16), e2117716119, 2022
242022
A Flexible Domain-Domain Hinge Promotes an Induced-fit Dominant Mechanism for the Loading of Guide-DNA into Argonaute Protein in Thermus thermophilus
L Zhu, H Jiang, FK Sheong, X Cui, X Gao, Y Wang, X Huang
The Journal of Physical Chemistry B 120 (10), 2709-2720, 2016
232016
Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns
G Chen, X Wang, Q Liao, Y Ge, H Jiao, Q Chen, Y Liu, W Lyu, L Zhu, ...
Nature communications 13 (1), 5232, 2022
222022
Elucidating dominant pathways of the nano-particle self-assembly process
X Zeng, B Li, Q Qiao, L Zhu, ZY Lu, X Huang
Physical Chemistry Chemical Physics 18 (34), 23494-23499, 2016
202016
Elucidation of the conformational dynamics of multi-body systems by construction of Markov state models
L Zhu, FK Sheong, X Zeng, X Huang
Physical Chemistry Chemical Physics 18 (44), 30228-30235, 2016
202016
TAPS: A traveling-salesman based automated path searching method for functional conformational changes of biological macromolecules
L Zhu, FK Sheong, S Cao, S Liu, IC Unarta, X Huang
The Journal of Chemical Physics 150 (12), 2019
192019
The HAMP signal relay domain adopts multiple conformational states through collective piston and tilt motions
L Zhu, PG Bolhuis, J Vreede
PLOS Computational Biology 9 (2), e1002913, 2013
182013
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