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Jonas Mårtensson
Jonas Mårtensson
MD, PhD-student
No verified email
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Similarities and differences between the responses induced in human phagocytes through activation of the medium chain fatty acid receptor GPR84 and the short chain fatty acid …
M Sundqvist, K Christenson, A Holdfeldt, M Gabl, J Mårtensson, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1865 (5), 695-708, 2018
452018
The neutrophil response induced by an agonist for free fatty acid receptor 2 (GPR43) is primed by tumor necrosis factor alpha and by receptor uncoupling from the cytoskeleton …
L Björkman, J Mårtensson, M Winther, M Gabl, A Holdfeldt, M Uhrbom, ...
Molecular and Cellular Biology 36 (20), 2583-2595, 2016
432016
Neutrophil signaling that challenges dogmata of G protein-coupled receptor regulated functions
C Dahlgren, A Holdfeldt, S Lind, J Mårtensson, M Gabl, L Björkman, ...
ACS Pharmacology & Translational Science 3 (2), 203-220, 2020
332020
Neutrophil priming that turns natural FFA2R agonists into potent activators of the superoxide generating NADPH-oxidase
J Mårtensson, A Holdfeldt, M Sundqvist, M Gabl, TP Kenakin, L Björkman, ...
Journal of Leukocyte Biology 104 (6), 1117-1132, 2018
292018
Functional selective ATP receptor signaling controlled by the free fatty acid receptor 2 through a novel allosteric modulation mechanism
S Lind, A Holdfeldt, J Mårtensson, M Sundqvist, L Björkman, H Forsman, ...
The FASEB Journal 33 (6), 6887-6903, 2019
262019
Mitocryptides from human mitochondrial DNA–encoded proteins activate neutrophil formyl peptide receptors: receptor preference and signaling properties
M Gabl, M Sundqvist, A Holdfeldt, S Lind, J Mårtensson, K Christenson, ...
The Journal of Immunology 200 (9), 3269-3282, 2018
222018
Neutrophil recruitment to inflamed joints can occur without cellular priming
L Björkman, K Christenson, L Davidsson, J Mårtensson, F Amirbeagi, ...
Journal of Leukocyte Biology 105 (6), 1123-1130, 2019
212019
Interdependent allosteric free fatty acid receptor 2 modulators synergistically induce functional selective activation and desensitization in neutrophils
S Lind, A Holdfeldt, J Mårtensson, M Sundqvist, TP Kenakin, L Björkman, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (6), 118689, 2020
202020
The two formyl peptide receptors differently regulate GPR84-mediated neutrophil NADPH oxidase activity
J Mårtensson, M Sundqvist, A Manandhar, L Ieremias, L Zhang, T Ulven, ...
Journal of Innate Immunity 13 (4), 242-256, 2021
152021
G protein coupled pattern recognition receptors expressed in neutrophils: recognition, activation/modulation, signaling and receptor regulated functions
C Dahlgren, S Lind, J Mårtensson, L Björkman, Y Wu, M Sundqvist, ...
Immunological Reviews 314 (1), 69-92, 2023
142023
Identification of Residues Critical for FPR2 Activation by the Cryptic Peptide Mitocryptide-2 Originating from the Mitochondrial DNA–Encoded Cytochrome b
S Lind, M Gabl, A Holdfeldt, J Mårtensson, M Sundqvist, K Nishino, ...
The Journal of Immunology 202 (9), 2710-2719, 2019
132019
GRK2 selectively attenuates the neutrophil NADPH-oxidase response triggered by β-arrestin recruiting GPR84 agonists
J Fredriksson, A Holdfeldt, J Mårtensson, L Björkman, TC Møller, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1869 (7), 119262, 2022
92022
Multiple ligand recognition sites in free fatty acid receptor 2 (FFA2R) direct distinct neutrophil activation patterns
S Lind, A Holdfeldt, J Mårtensson, KL Granberg, H Forsman, C Dahlgren
Biochemical Pharmacology 193, 114762, 2021
82021
Function and regulation of GPR84 in human neutrophils
H Forsman, C Dahlgren, J Mårtensson, L Björkman, M Sundqvist
British Journal of Pharmacology 181 (10), 1536-1549, 2024
72024
The ketone body acetoacetate activates human neutrophils through FFAR2
J Mårtensson, L Björkman, S Lind, MB Viklund, L Zhang, S Gutierrez, ...
Journal of Leukocyte Biology 113 (6), 577-587, 2023
52023
AZ2158 is a more potent formyl peptide receptor 1 inhibitor than the commonly used peptide antagonists in abolishing neutrophil chemotaxis
H Forsman, Y Wu, J Mårtensson, L Björkman, KL Granberg, C Dahlgren, ...
Biochemical Pharmacology 211, 115529, 2023
42023
AB0067 Allosteric receptor modulation of a free fatty acid receptor turns natural agonists into potent activators of the superoxide generating neutrophil nadph-oxidase
L Björkman, J Mårtensson, A Holdfeldt, H Forsman, M Gabl, M Sundqvist, ...
Annals of the Rheumatic Diseases 77 (Suppl 2), 1232-1232, 2018
12018
Interdependent Allosteric FFA2R Modulators Synergistically Induce Functional Selective Activation and Desensitization in Neutrophils
S Lind, A Holdfeldt, J Mårtensson, M Sundqvist, TP Kenakin, L Björkman, ...
bioRxiv, 809061, 2019
2019
Allosteric receptor modulation of FFA2R turns natural agonists into potent activators of the superoxide generating neutrophil NADPH-oxidase
J Mårtensson, A Holdfeldt, M Sundqvist, M Gabl, L Björkman, H Forsman, ...
bioRxiv, 284935, 2018
2018
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