A review of PAT strategies in secondary solid oral dosage manufacturing of small molecules S Laske, A Paudel, O Scheibelhofer, S Sacher, T Hoermann, J Khinast, ... Journal of pharmaceutical sciences 106 (3), 667-712, 2017 | 88 | 2017 |
Raw material variability of an active pharmaceutical ingredient and its relevance for processability in secondary continuous pharmaceutical manufacturing F Stauffer, V Vanhoorne, G Pilcer, PF Chavez, S Rome, MA Schubert, ... European Journal of Pharmaceutics and Biopharmaceutics 127, 92-103, 2018 | 54 | 2018 |
Managing API raw material variability in a continuous manufacturing line–Prediction of process robustness F Stauffer, V Vanhoorne, G Pilcer, PF Chavez, C Vervaet, T De Beer International Journal of Pharmaceutics 569, 118525, 2019 | 32 | 2019 |
Managing active pharmaceutical ingredient raw material variability during twin-screw blend feeding F Stauffer, V Vanhoorne, G Pilcer, PF Chavez, MA Schubert, C Vervaet, ... European Journal of Pharmaceutics and Biopharmaceutics 135, 49-60, 2019 | 31 | 2019 |
Managing API raw material variability during continuous twin-screw wet granulation F Stauffer, V Vanhoorne, G Pilcer, PF Chavez, C Vervaet, T De Beer International Journal of Pharmaceutics 561, 265-273, 2019 | 26 | 2019 |
Feeding of particle-based materials in continuous solid dosage manufacturing: a material science perspective WK Hsiao, TR Hörmann, P Toson, A Paudel, P Ghiotti, F Stauffer, F Bauer, ... Drug Discovery Today 25 (4), 800-806, 2020 | 21 | 2020 |
Heat transfer evaluation during twin-screw wet granulation in view of detailed process understanding F Stauffer, A Ryckaert, D Van Hauwermeiren, A Funke, D Djuric, I Nopens, ... Aaps Pharmscitech 20, 1-13, 2019 | 17 | 2019 |
Evaluation of torque as an in-process control for granule size during twin-screw wet granulation A Ryckaert, F Stauffer, A Funke, D Djuric, V Vanhoorne, C Vervaet, ... International Journal of Pharmaceutics 602, 120642, 2021 | 15 | 2021 |
Polyelectrolytes layer-by-layer surface modification of PDMS microchips for the production of simple O/W and double W/O/W emulsions: From global to localized treatment F Stauffer, B Peter, H Alem, D Funfschilling, N Dumas, CA Serra, ... Chemical Engineering and Processing-Process Intensification 146, 107685, 2019 | 12 | 2019 |
The use of partially hydrolysed polyvinyl alcohol for the production of high drug-loaded sustained release pellets via extrusion-spheronisation and coating: In vitro and in … G Verstraete, W De Jaeghere, J Vercruysse, W Grymonpré, V Vanhoorne, ... International Journal of Pharmaceutics 517 (1-2), 88-95, 2017 | 12 | 2017 |
La préparation d’émulsions doubles par un système microfluidique F Stauffer Sciences pharma-ceutiques, 2014 | 10 | 2014 |
Evaluation of the influence of material properties and process parameters on granule porosity in twin-screw wet granulation M Peeters, AAB Jiménez, K Matsunami, F Stauffer, I Nopens, T De Beer International Journal of Pharmaceutics 641, 123010, 2023 | 7 | 2023 |
Linking material properties to 1D-PBM parameters towards a generic model for twin-screw wet granulation AAB Jiménez, K Matsunami, D Van Hauwermeiren, M Peeters, F Stauffer, ... Chemical Engineering Research and Design 193, 713-724, 2023 | 6 | 2023 |
Sampling and diversion strategy for twin-screw granulation lines using batch statistical process monitoring F Stauffer, E Boulanger, G Pilcer European Journal of Pharmaceutical Sciences 171, 106126, 2022 | 6 | 2022 |
Analysis of the effect of formulation properties and process parameters on granule formation in twin-screw wet granulation M Peeters, AAB Jiménez, K Matsunami, M Ghijs, E dos Santos Schultz, ... International Journal of Pharmaceutics 650, 123671, 2024 | 4 | 2024 |
Mechanistic modeling of semicontinuous fluidized bed drying of pharmaceutical granules by incorporating single particle and bulk drying kinetics T Vandeputte, M Ghijs, D Van Hauwermeiren, EDS Schultz, E Schäfer, ... International Journal of Pharmaceutics 646, 123447, 2023 | 4 | 2023 |
Partial least squares regression to calculate population balance model parameters from material properties in continuous twin-screw wet granulation AAB Jiménez, K Matsunami, D Van Hauwermeiren, M Peeters, F Stauffer, ... International Journal of Pharmaceutics 640, 123040, 2023 | 4 | 2023 |
Model development and calibration of two-dimensional population balance model for twin-screw wet granulation based on particle size distribution and porosity AAB Jiménez, K Matsunami, M Ghijs, D Van Hauwermeiren, M Peeters, ... Powder Technology 419, 118334, 2023 | 4 | 2023 |
Predicting powder feedability: a workflow for assessing the risk of flow stagnation and defining the operating space for different powder-feeder combinations TR Hörmann-Kincses, M Beretta, J Kruisz, F Stauffer, G Birk, PM Piccione, ... International Journal of Pharmaceutics 629, 122364, 2022 | 4 | 2022 |
Control strategy definition for a drug product continuous wet granulation process: Industrial case study PF Chavez, F Stauffer, F Eeckman, N Bostijn, D Didion, C Schaefer, ... International Journal of Pharmaceutics 624, 121970, 2022 | 4 | 2022 |