Haptoglobin administration into the subarachnoid space prevents hemoglobin-induced cerebral vasospasm M Hugelshofer, RM Buzzi, CA Schaer, H Richter, K Akeret, ... The Journal of clinical investigation 129 (12), 5219-5235, 2019 | 72 | 2019 |
Hemolysis transforms liver macrophages into anti-inflammatory erythrophagocytes M Pfefferlé, G Ingoglia, CA Schaer, A Yalamanoglu, RM Buzzi, IL Dubach, ... The Journal of Clinical Investigation, 2020 | 57 | 2020 |
Cerebrospinal fluid hemoglobin drives subarachnoid hemorrhage-related secondary brain injury K Akeret, RM Buzzi, CA Schaer, BR Thomson, F Vallelian, S Wang, ... Journal of Cerebral Blood Flow & Metabolism 41 (11), 3000-3015, 2021 | 42 | 2021 |
Cell-free oxyhemoglobin in cerebrospinal fluid after aneurysmal subarachnoid hemorrhage: biomarker and potential therapeutic target M Hugelshofer, CM Sikorski, M Seule, J Deuel, CI Muroi, M Seboek, ... World neurosurgery 120, e660-e666, 2018 | 32 | 2018 |
Serotonin promotes acinar dedifferentiation following pancreatitis‐induced regeneration in the adult pancreas E Saponara, K Grabliauskaite, M Bombardo, R Buzzi, AB Silva, ... The Journal of pathology 237 (4), 495-507, 2015 | 24 | 2015 |
The oral ferroportin inhibitor vamifeport improves hemodynamics in a mouse model of sickle cell disease N Nyffenegger, R Zennadi, N Kalleda, A Flace, G Ingoglia, RM Buzzi, ... Blood, The Journal of the American Society of Hematology 140 (7), 769-781, 2022 | 22 | 2022 |
Spatial transcriptome analysis defines heme as a hemopexin-targetable inflammatoxin in the brain RM Buzzi, K Akeret, N Schwendinger, J Klohs, F Vallelian, M Hugelshofer, ... Free Radical Biology and Medicine 179, 277-287, 2022 | 19 | 2022 |
Heme-stress activated NRF2 skews fate trajectories of bone marrow cells from dendritic cells towards red pulp-like macrophages in hemolytic anemia F Vallelian, RM Buzzi, M Pfefferlé, A Yalamanoglu, IL Dubach, A Wassmer, ... Cell Death & Differentiation 29 (8), 1450-1465, 2022 | 17 | 2022 |
Hemopexin dosing improves cardiopulmonary dysfunction in murine sickle cell disease PW Buehler, D Swindle, DI Pak, SM Majka, V Karoor, R Moldovan, ... Free Radical Biology and Medicine 175, 95-107, 2021 | 15 | 2021 |
Modular Platform for the Development of Recombinant Hemoglobin Scavenger Biotherapeutics RM Buzzi, CM Owczarek, K Akeret, A Tester, N Pereira, R Butcher, ... Molecular Pharmaceutics 18 (8), 3158-3170, 2021 | 9 | 2021 |
Hemorrhage-activated NRF2 in tumor-associated macrophages drives cancer growth, invasion, and immunotherapy resistance DJ Schaer, N Schulthess-Lutz, L Baselgia, K Hansen, RM Buzzi, E Dürst, ... The Journal of Clinical Investigation 134 (3), 2024 | 8 | 2024 |
Antibody-induced erythrophagocyte reprogramming of Kupffer cells prevents anti-CD40 cancer immunotherapy-associated liver toxicity M Pfefferlé, IL Dubach, RM Buzzi, E Dürst, N Schulthess-Lutz, L Baselgia, ... Journal for Immunotherapy of Cancer 11 (1), 2023 | 8 | 2023 |
MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and secondary brain edema in a mouse model of intracerebral hemorrhage K Akeret, RM Buzzi, BR Thomson, N Schwendinger, J Klohs, ... Journal of Neuroinflammation 19 (1), 290, 2022 | 7 | 2022 |
Spatial transcriptome data from coronal mouse brain sections after striatal injection of heme and heme-hemopexin K Akeret, M Hugelshofer, DJ Schaer, RM Buzzi Data in brief 41, 107866, 2022 | 7 | 2022 |
The HeMoVal study protocol: a prospective international multicenter cohort study to validate cerebrospinal fluid hemoglobin as a monitoring biomarker for aneurysmal … K Akeret, RM Buzzi, M Saxenhofer, K Bieri, D Chiavi, BR Thomson, ... BMC neurology 22 (1), 267, 2022 | 5 | 2022 |
A model to visualize the fate of iron after intracranial hemorrhage using isotopic tracers and elemental bioimaging P Bücker, RM Buzzi, K Akeret, L Mosberger, H Richter, M Sperling, ... Metallomics 14 (8), mfac057, 2022 | 3 | 2022 |
Determining the Optimal Normalization Factor of Different Target Arteries for ex vivo Vascular Function Experiments: A New Standardized Procedure M Hugelshofer, JW Deuel, RM Buzzi, R Humar, DJ Schaer, CA Schaer Journal of vascular research 57 (2), 106-112, 2020 | 3 | 2020 |
Clinical potential of automated convolutional neural network-based hematoma volumetry after aneurysmal subarachnoid hemorrhage BR Thomson, F Gürlek, RM Buzzi, N Schwendinger, E Keller, L Regli, ... Journal of Stroke and Cerebrovascular Diseases 32 (11), 107357, 2023 | 2 | 2023 |
Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity BR Thomson, H Richter, K Akeret, RM Buzzi, V Anagnostakou, ... Journal of Stroke and Cerebrovascular Diseases 32 (3), 106985, 2023 | 2 | 2023 |
Multimodal anatomy of the human forniceal commissure K Akeret, SJ Forkel, RM Buzzi, F Vasella, I Amrein, G Colacicco, C Serra, ... Communications biology 5 (1), 1-11, 2022 | 2 | 2022 |