| Comparison of the exposure time dependence of the activities of synthetic ozonide antimalarials and dihydroartemisinin against K13 wild-type and mutant Plasmodium falciparum … T Yang, SC Xie, P Cao, C Giannangelo, J McCaw, DJ Creek, ... Antimicrobial agents and chemotherapy 60 (8), 4501-4510, 2016 | 60 | 2016 |
| Ozonide antimalarial activity in the context of artemisinin-resistant malaria C Giannangelo, FJI Fowkes, JA Simpson, SA Charman, DJ Creek Trends in parasitology 35 (7), 529-543, 2019 | 48 | 2019 |
| Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy SC Xie, RD Metcalfe, E Dunn, CJ Morton, SC Huang, T Puhalovich, Y Du, ... Science 376 (6597), 1074-1079, 2022 | 31 | 2022 |
| Peroxide Antimalarial Drugs Target Redox Homeostasis in Plasmodium falciparum Infected Red Blood Cells G Siddiqui, C Giannangelo, A De Paoli, AK Schuh, KC Heimsch, ... ACS infectious diseases 8 (1), 210-226, 2022 | 25 | 2022 |
| System-wide biochemical analysis reveals ozonide antimalarials initially act by disrupting Plasmodium falciparum haemoglobin digestion C Giannangelo, G Siddiqui, A De Paoli, BM Anderson, ... PLoS Pathogens 16 (6), e1008485, 2020 | 22 | 2020 |
| Parasite-Mediated Degradation of Synthetic Ozonide Antimalarials Impacts In Vitro Antimalarial Activity C Giannangelo, L Stingelin, T Yang, L Tilley, SA Charman, DJ Creek Antimicrobial Agents and Chemotherapy 62 (3), 10.1128/aac. 01566-17, 2018 | 16 | 2018 |
| Ozonide Antimalarials Alkylate Heme in the Malaria Parasite Plasmodium falciparum C Giannangelo, D Anderson, X Wang, JL Vennerstrom, SA Charman, ... ACS infectious diseases 5 (12), 2076-2086, 2019 | 15 | 2019 |
| Dimeric artesunate glycerophosphocholine conjugate nano-assemblies as slow-release antimalarials to overcome Kelch 13 mutant artemisinin resistance Y Du, C Giannangelo, W He, GJ Shami, W Zhou, T Yang, DJ Creek, ... Antimicrobial Agents and Chemotherapy 66 (5), e02065-21, 2022 | 11 | 2022 |
| The role of metabolomics in antiparasitic drug discovery CR Giannangelo, KM Ellis, AE Sexton, D Stoessel, DJ Creek Comprehensive Analysis of Parasite Biology: From Metabolism to Drug …, 2016 | 5 | 2016 |
| Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as an antimalarial strategy D Creek, C Giannangelo, M Challis, G Siddiqui, R Edgar, T Malcolm, ... eLife 13, 2024 | 1 | 2024 |
| On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity RCS Edgar, TR Malcolm, G Siddiqui, C Giannangelo, NA Counihan, ... Mbio, e00966-24, 2024 | | 2024 |
| Promising antimalarial hits from phenotypic screens: a review of recently-described multi-stage actives and their modes of action AP Luo, C Giannangelo, G Siddiqui, DJ Creek Frontiers in Cellular and Infection Microbiology 13, 2023 | | 2023 |
| [KEYNOTE] Defining complex drug mechanisms with metabolomics (Video) D Creek, C Giannangelo, G Siddiqui, S Charman MDPI AG, 2018 | | 2018 |
| Biochemical pathways and molecular targets involved in the mechanism of action of ozonide antimalarials in Plasmodium falciparum C GIANNANGELO Monash University, 2018 | | 2018 |
| PHYSIOLOGICALLY RELEVANT EXPOSURE TO SYNTHETIC OZONIDE ANTIMALARIALS KILLS K13 WILDTYPE AND MUTANT PLASMODIUM FALCIPARUM MORE EFFECTIVELY THAN DIHYDROARTEMISININ T Yang, SC Xie, P Cao, C Giannangelo, J McCaw, DJ Creek, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 95 (5), 78-78, 2017 | | 2017 |
