| Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules BJ Moeller, Y Cao, CY Li, MW Dewhirst Cancer cell 5 (5), 429-441, 2004 | 997 | 2004 |
| Caspase 3–mediated stimulation of tumor cell repopulation during cancer radiotherapy Q Huang, F Li, X Liu, W Li, W Shi, FF Liu, B O'sullivan, Z He, Y Peng, ... Nature medicine 17 (7), 860-866, 2011 | 618 | 2011 |
| Regulation of HIF-1α stability through S-nitrosylation F Li, P Sonveaux, ZN Rabbani, S Liu, B Yan, Q Huang, Z Vujaskovic, ... Molecular cell 26 (1), 63-74, 2007 | 460 | 2007 |
| Initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent models CY Li, S Shan, Q Huang, RD Braun, J Lanzen, K Hu, P Lin, MW Dewhirst Journal of the National Cancer Institute 92 (2), 143-147, 2000 | 442 | 2000 |
| Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity BJ Moeller, MR Dreher, ZN Rabbani, T Schroeder, Y Cao, CY Li, ... Cancer cell 8 (2), 99-110, 2005 | 417 | 2005 |
| Apoptotic cells activate the “phoenix rising” pathway to promote wound healing and tissue regeneration F Li, Q Huang, J Chen, Y Peng, DR Roop, JS Bedford, CY Li Science signaling 3 (110), ra13-ra13, 2010 | 407 | 2010 |
| Potential role of WAF1/Cip1/p21 as a mediator of TGF-β cytoinhibitory effect CY Li, L Suardet, JB Little Journal of Biological Chemistry 270 (10), 4971-4974, 1995 | 290 | 1995 |
| Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells X Liu, F Li, EA Stubblefield, B Blanchard, TL Richards, GA Larson, Y He, ... Cell research 22 (2), 321-332, 2012 | 175 | 2012 |
| Heat-induced gene expression as a novel targeted cancer gene therapy strategy Q Huang, JK Hu, F Lohr, L Zhang, R Braun, J Lanzen, JB Little, ... Cancer research 60 (13), 3435-3439, 2000 | 170 | 2000 |
| GW112, a novel antiapoptotic protein that promotes tumor growth X Zhang, Q Huang, Z Yang, Y Li, CY Li Cancer research 64 (7), 2474-2481, 2004 | 154 | 2004 |
| Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status JB Little, H Nagasawa, PC Keng, Y Yu, CY Li Journal of Biological Chemistry 270 (19), 11033-11036, 1995 | 152 | 1995 |
| Enhancement of hypoxia-induced tumor cell death in vitro and radiation therapy in vivo by use of small interfering RNA targeted to hypoxia-inducible factor-1α X Zhang, T Kon, H Wang, F Li, Q Huang, ZN Rabbani, JP Kirkpatrick, ... Cancer research 64 (22), 8139-8142, 2004 | 150 | 2004 |
| Effective tumor therapy with plasmid-encoded cytokines combined with in vivo electroporation F Lohr, DY Lo, DA Zaharoff, K Hu, X Zhang, Y Li, Y Zhao, MW Dewhirst, ... Cancer research 61 (8), 3281-3284, 2001 | 150 | 2001 |
| Tumor necrosis factor-α is a potent endogenous mutagen that promotes cellular transformation B Yan, H Wang, ZN Rabbani, Y Zhao, W Li, Y Yuan, F Li, MW Dewhirst, ... Cancer Research 66 (24), 11565-11570, 2006 | 148 | 2006 |
| Tetrandrine inhibits Wnt/β-catenin signaling and suppresses tumor growth of human colorectal cancer BC He, JL Gao, BQ Zhang, Q Luo, Q Shi, SH Kim, E Huang, Y Gao, ... Molecular pharmacology 79 (2), 211-219, 2011 | 144 | 2011 |
| Caspase-3 promotes genetic instability and carcinogenesis X Liu, Y He, F Li, Q Huang, TA Kato, RP Hall, CY Li Molecular cell 58 (2), 284-296, 2015 | 139 | 2015 |
| Systemic overexpression of angiopoietin-2 promotes tumor microvessel regression and inhibits angiogenesis and tumor growth Y Cao, P Sonveaux, S Liu, Y Zhao, J Mi, BM Clary, CY Li, CD Kontos, ... Cancer research 67 (8), 3835-3844, 2007 | 121 | 2007 |
| Observation of incipient tumor angiogenesis that is independent of hypoxia and hypoxia inducible factor-1 activation Y Cao, CY Li, BJ Moeller, D Yu, Y Zhao, MR Dreher, S Shan, ... Cancer research 65 (13), 5498-5505, 2005 | 118 | 2005 |
| GRP94 (gp96) and GRP94 N-Terminal Geldanamycin Binding Domain Elicit Tissue Nonrestricted Tumor Suppression JC Baker-LePain, M Sarzotti, TA Fields, CY Li, CV Nicchitta The Journal of experimental medicine 196 (11), 1447-1459, 2002 | 117 | 2002 |
| Abrogation of p53 function by transfection of HPV16 E6 gene enhances the resistance of human diploid fibroblasts to ionizing radiation. NM Tsang, H Nagasawa, C Li, JB Little Oncogene 10 (12), 2403, 1995 | 117 | 1995 |
John B. LittleProfessor HarvardVerified email at hsph.harvard.edu
