Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers M Soula, RA Weber, O Zilka, H Alwaseem, K La, F Yen, H Molina, ... Nature chemical biology 16 (12), 1351-1360, 2020 | 400 | 2020 |
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation RA Weber, FS Yen, SPV Nicholson, H Alwaseem, EC Bayraktar, M Alam, ... Molecular cell 77 (3), 645-655. e7, 2020 | 167 | 2020 |
Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior J Blaze, A Navickas, HL Phillips, S Heissel, A Plaza-Jennings, S Miglani, ... Nature communications 12 (1), 4913, 2021 | 53 | 2021 |
Anticancer activity profiling of parthenolide analogs generated via P450-mediated chemoenzymatic synthesis H Alwaseem, BJ Frisch, R Fasan Bioorganic & medicinal chemistry 26 (7), 1365-1373, 2018 | 39 | 2018 |
Catalytic transfer hydrogenation of castor oil H Alwaseem, CJ Donahue, S Marincean Journal of Chemical Education 91 (4), 575-578, 2014 | 38 | 2014 |
Chemoenzymatic synthesis and antileukemic activity of novel C9-and C14-functionalized parthenolide analogs V Tyagi, H Alwaseem, KM O’Dwyer, J Ponder, QY Li, CT Jordan, R Fasan Bioorganic & medicinal chemistry 24 (17), 3876-3886, 2016 | 37 | 2016 |
Metabolic coessentiality mapping identifies C12orf49 as a regulator of SREBP processing and cholesterol metabolism EC Bayraktar, K La, K Karpman, G Unlu, C Ozerdem, DJ Ritter, ... Nature metabolism 2 (6), 487-498, 2020 | 36 | 2020 |
A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs X Liu, W Mei, V Padmanaban, H Alwaseem, H Molina, MC Passarelli, ... Molecular cell 82 (14), 2604-2617. e8, 2022 | 35 | 2022 |
Analysis of the mechanosensor channel functionality of TACAN Y Niu, X Tao, G Vaisey, PDB Olinares, H Alwaseem, BT Chait, ... Elife 10, e71188, 2021 | 33 | 2021 |
Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxia J Garcia-Bermudez, MA Badgley, S Prasad, L Baudrier, Y Liu, K La, ... Nature metabolism 4 (6), 724-738, 2022 | 25 | 2022 |
The pupal moulting fluid has evolved social functions in ants O Snir, H Alwaseem, S Heissel, A Sharma, S Valdés-Rodríguez, ... Nature 612 (7940), 488-494, 2022 | 24 | 2022 |
A deep intronic splice mutation of STAT3 underlies hyper IgE syndrome by negative dominance J Khourieh, G Rao, T Habib, DT Avery, A Lefèvre-Utile, MO Chandesris, ... Proceedings of the National Academy of Sciences 116 (33), 16463-16472, 2019 | 24 | 2019 |
Stabilization of the Reductase Domain in the Catalytically Self‐Sufficient Cytochrome P450BM3 by Consensus‐Guided Mutagenesis G Saab‐Rincón, H Alwaseem, V Guzmán‐Luna, L Olvera, R Fasan ChemBioChem 19 (6), 622-632, 2018 | 22 | 2018 |
Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals TC Kenny, A Khan, Y Son, L Yue, S Heissel, A Sharma, HA Pasolli, Y Liu, ... Cell metabolism 35 (6), 1057-1071. e12, 2023 | 21 | 2023 |
Comprehensive Structure–Activity Profiling of Micheliolide and its Targeted Proteome in Leukemia Cells via Probe-Guided Late-Stage C–H Functionalization H Alwaseem, S Giovani, M Crotti, K Welle, CT Jordan, S Ghaemmaghami, ... ACS Central Science 7 (5), 841-857, 2021 | 21 | 2021 |
Aldehyde and Ketone Synthesis by P450‐Catalyzed Oxidative Deamination of Alkyl Azides S Giovani, H Alwaseem, R Fasan ChemCatChem 8 (16), 2609-2613, 2016 | 18 | 2016 |
ALKBH7 mediates necrosis via rewiring of glyoxal metabolism CA Kulkarni, SM Nadtochiy, L Kennedy, J Zhang, S Chhim, H Alwaseem, ... Elife 9, e58573, 2020 | 17 | 2020 |
Autoregulatory control of mitochondrial glutathione homeostasis Y Liu, S Liu, A Tomar, FS Yen, G Unlu, N Ropek, RA Weber, Y Wang, ... Science 382 (6672), 820-828, 2023 | 14 | 2023 |
Dietary thiamine influences l-asparaginase sensitivity in a subset of leukemia cells R Guarecuco, RT Williams, L Baudrier, K La, MC Passarelli, N Ekizoglu, ... Science Advances 6 (41), eabc7120, 2020 | 12 | 2020 |
Systemic adeno-associated virus-mediated gene therapy prevents the multiorgan disorders associated with aldehyde dehydrogenase 2 deficiency and chronic ethanol ingestion Y Matsumura, N Li, H Alwaseem, OE Pagovich, RG Crystal, ... Human Gene Therapy 31 (3-4), 163-182, 2020 | 8 | 2020 |