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Hanan Alwaseem
Hanan Alwaseem
University of Rochester, Rockefeller University
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Year
Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
M Soula, RA Weber, O Zilka, H Alwaseem, K La, F Yen, H Molina, ...
Nature chemical biology 16 (12), 1351-1360, 2020
4002020
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation
RA Weber, FS Yen, SPV Nicholson, H Alwaseem, EC Bayraktar, M Alam, ...
Molecular cell 77 (3), 645-655. e7, 2020
1672020
Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior
J Blaze, A Navickas, HL Phillips, S Heissel, A Plaza-Jennings, S Miglani, ...
Nature communications 12 (1), 4913, 2021
532021
Anticancer activity profiling of parthenolide analogs generated via P450-mediated chemoenzymatic synthesis
H Alwaseem, BJ Frisch, R Fasan
Bioorganic & medicinal chemistry 26 (7), 1365-1373, 2018
392018
Catalytic transfer hydrogenation of castor oil
H Alwaseem, CJ Donahue, S Marincean
Journal of Chemical Education 91 (4), 575-578, 2014
382014
Chemoenzymatic synthesis and antileukemic activity of novel C9-and C14-functionalized parthenolide analogs
V Tyagi, H Alwaseem, KM O’Dwyer, J Ponder, QY Li, CT Jordan, R Fasan
Bioorganic & medicinal chemistry 24 (17), 3876-3886, 2016
372016
Metabolic coessentiality mapping identifies C12orf49 as a regulator of SREBP processing and cholesterol metabolism
EC Bayraktar, K La, K Karpman, G Unlu, C Ozerdem, DJ Ritter, ...
Nature metabolism 2 (6), 487-498, 2020
362020
A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
X Liu, W Mei, V Padmanaban, H Alwaseem, H Molina, MC Passarelli, ...
Molecular cell 82 (14), 2604-2617. e8, 2022
352022
Analysis of the mechanosensor channel functionality of TACAN
Y Niu, X Tao, G Vaisey, PDB Olinares, H Alwaseem, BT Chait, ...
Elife 10, e71188, 2021
332021
Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxia
J Garcia-Bermudez, MA Badgley, S Prasad, L Baudrier, Y Liu, K La, ...
Nature metabolism 4 (6), 724-738, 2022
252022
The pupal moulting fluid has evolved social functions in ants
O Snir, H Alwaseem, S Heissel, A Sharma, S Valdés-Rodríguez, ...
Nature 612 (7940), 488-494, 2022
242022
A deep intronic splice mutation of STAT3 underlies hyper IgE syndrome by negative dominance
J Khourieh, G Rao, T Habib, DT Avery, A Lefèvre-Utile, MO Chandesris, ...
Proceedings of the National Academy of Sciences 116 (33), 16463-16472, 2019
242019
Stabilization of the Reductase Domain in the Catalytically Self‐Sufficient Cytochrome P450BM3 by Consensus‐Guided Mutagenesis
G Saab‐Rincón, H Alwaseem, V Guzmán‐Luna, L Olvera, R Fasan
ChemBioChem 19 (6), 622-632, 2018
222018
Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals
TC Kenny, A Khan, Y Son, L Yue, S Heissel, A Sharma, HA Pasolli, Y Liu, ...
Cell metabolism 35 (6), 1057-1071. e12, 2023
212023
Comprehensive Structure–Activity Profiling of Micheliolide and its Targeted Proteome in Leukemia Cells via Probe-Guided Late-Stage C–H Functionalization
H Alwaseem, S Giovani, M Crotti, K Welle, CT Jordan, S Ghaemmaghami, ...
ACS Central Science 7 (5), 841-857, 2021
212021
Aldehyde and Ketone Synthesis by P450‐Catalyzed Oxidative Deamination of Alkyl Azides
S Giovani, H Alwaseem, R Fasan
ChemCatChem 8 (16), 2609-2613, 2016
182016
ALKBH7 mediates necrosis via rewiring of glyoxal metabolism
CA Kulkarni, SM Nadtochiy, L Kennedy, J Zhang, S Chhim, H Alwaseem, ...
Elife 9, e58573, 2020
172020
Autoregulatory control of mitochondrial glutathione homeostasis
Y Liu, S Liu, A Tomar, FS Yen, G Unlu, N Ropek, RA Weber, Y Wang, ...
Science 382 (6672), 820-828, 2023
142023
Dietary thiamine influences l-asparaginase sensitivity in a subset of leukemia cells
R Guarecuco, RT Williams, L Baudrier, K La, MC Passarelli, N Ekizoglu, ...
Science Advances 6 (41), eabc7120, 2020
122020
Systemic adeno-associated virus-mediated gene therapy prevents the multiorgan disorders associated with aldehyde dehydrogenase 2 deficiency and chronic ethanol ingestion
Y Matsumura, N Li, H Alwaseem, OE Pagovich, RG Crystal, ...
Human Gene Therapy 31 (3-4), 163-182, 2020
82020
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Articles 1–20