Clustering of aromatic residues in prion-like domains can tune the formation, state, and organization of biomolecular condensates: published as part of the biochemistry virtual … AS Holehouse, GM Ginell, D Griffith, E Boke Biochemistry 60 (47), 3566-3581, 2021 | 64 | 2021 |
Revealing the hidden sensitivity of intrinsically disordered proteins to their chemical environment D Moses, F Yu, GM Ginell, NM Shamoon, PS Koenig, AS Holehouse, ... The journal of physical chemistry letters 11 (23), 10131-10136, 2020 | 55 | 2020 |
Conservation of structure and immune antagonist functions of filoviral VP35 homologs present in microbat genomes MR Edwards, H Liu, RS Shabman, GM Ginell, P Luthra, P Ramanan, ... Cell reports 24 (4), 861-872. e6, 2018 | 22 | 2018 |
Intrinsically disordered regions are poised to act as sensors of cellular chemistry D Moses, GM Ginell, AS Holehouse, S Sukenik Trends in biochemical sciences, 2023 | 20 | 2023 |
An introduction to the stickers-and-spacers framework as applied to biomolecular condensates GM Ginell, AS Holehouse Phase-Separated Biomolecular Condensates: Methods and Protocols, 95-116, 2022 | 19 | 2022 |
Direct prediction of intrinsically disordered protein conformational properties from sequence JM Lotthammer, GM Ginell, D Griffith, R Emenecker, AS Holehouse Biophysical Journal 123 (3), 43a, 2024 | 18 | 2024 |
Analyzing the sequences of intrinsically disordered regions with CIDER and localCIDER GM Ginell, AS Holehouse Intrinsically Disordered Proteins: Methods and Protocols, 103-126, 2020 | 12 | 2020 |
The analytical Flory random coil is a simple-to-use reference model for unfolded and disordered proteins JJ Alston, GM Ginell, A Soranno, AS Holehouse The Journal of Physical Chemistry B 127 (21), 4746-4760, 2023 | 8 | 2023 |
Aberrant phase separation is a common killing strategy of positively charged peptides in biology and human disease S Boeynaems, XR Ma, V Yeong, GM Ginell, JH Chen, JA Blum, ... bioRxiv, 2023 | 7 | 2023 |
The formation of a fuzzy complex in the negative arm regulates the robustness of the circadian clock MS Jankowski, D Griffith, DG Shastry, JF Pelham, GM Ginell, J Thomas, ... bioRxiv, 2022.01. 04.474980, 2022 | 5 | 2022 |
SHEPHARD: a modular and extensible software architecture for analyzing and annotating large protein datasets GM Ginell, AJ Flynn, AS Holehouse Bioinformatics 39 (8), btad488, 2023 | 3 | 2023 |
Probing the hidden sensitivity of intrinsically disordered proteins to their chemical environment D Moses, F Yu, GM Ginell, NM Shamoon, PS Koenig, AS Holehouse, ... biorxiv, 2020.08. 17.252478, 2020 | 3 | 2020 |
Labile assembly of a tardigrade protein induces biostasis S Sanchez-Martinez, K Nguyen, S Biswas, V Nicholson, AV Romanyuk, ... bioRxiv, 2023.06. 30.547219, 2023 | 2 | 2023 |
Helicity of a tardigrade disordered protein promotes desiccation tolerance S Biswas, E Gollub, F Yu, G Ginell, AS Holehouse, S Sukenik, TC Boothby bioRxiv, 2023.07. 06.548010, 2023 | 1 | 2023 |
Disordered clock protein interactions and charge blocks turn an hourglass into a persistent circadian oscillator MS Jankowski, D Griffith, DG Shastry, JF Pelham, GM Ginell, J Thomas, ... Nature Communications 15 (1), 3523, 2024 | | 2024 |
Helicity of a tardigrade disordered protein contributes to its protective function during desiccation S Biswas, E Gollub, F Yu, G Ginell, A Holehouse, S Sukenik, TC Boothby Protein Science 33 (2), e4872, 2024 | | 2024 |
Intramolecular and intermolecular effects of aromatic sticker residue strength on intrinsically disordered protein regions D Moses, GM Ginell, AS Holehouse, S Sukenik Biophysical Journal 122 (3), 62a, 2023 | | 2023 |
Understanding the Chemical Context of Interactions in Intrinsically Disordered Proteins G Ginell | | 2023 |
Hyperphosphorylation tunes TDP‐43 solubility GM Ginell, AS Holehouse The EMBO Journal 41 (8), e111062, 2022 | | 2022 |
A fuzzy complex in the negative arm regulates circadian clock robustness. J Hurley, M Jankowski, D Griffith, D Shastry, J Pelham, G Ginell, J Thomas, ... | | 2022 |