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Garrett M. Ginell
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Clustering of aromatic residues in prion-like domains can tune the formation, state, and organization of biomolecular condensates: published as part of the biochemistry virtual …
AS Holehouse, GM Ginell, D Griffith, E Boke
Biochemistry 60 (47), 3566-3581, 2021
642021
Revealing the hidden sensitivity of intrinsically disordered proteins to their chemical environment
D Moses, F Yu, GM Ginell, NM Shamoon, PS Koenig, AS Holehouse, ...
The journal of physical chemistry letters 11 (23), 10131-10136, 2020
552020
Conservation of structure and immune antagonist functions of filoviral VP35 homologs present in microbat genomes
MR Edwards, H Liu, RS Shabman, GM Ginell, P Luthra, P Ramanan, ...
Cell reports 24 (4), 861-872. e6, 2018
222018
Intrinsically disordered regions are poised to act as sensors of cellular chemistry
D Moses, GM Ginell, AS Holehouse, S Sukenik
Trends in biochemical sciences, 2023
202023
An introduction to the stickers-and-spacers framework as applied to biomolecular condensates
GM Ginell, AS Holehouse
Phase-Separated Biomolecular Condensates: Methods and Protocols, 95-116, 2022
192022
Direct prediction of intrinsically disordered protein conformational properties from sequence
JM Lotthammer, GM Ginell, D Griffith, R Emenecker, AS Holehouse
Biophysical Journal 123 (3), 43a, 2024
182024
Analyzing the sequences of intrinsically disordered regions with CIDER and localCIDER
GM Ginell, AS Holehouse
Intrinsically Disordered Proteins: Methods and Protocols, 103-126, 2020
122020
The analytical Flory random coil is a simple-to-use reference model for unfolded and disordered proteins
JJ Alston, GM Ginell, A Soranno, AS Holehouse
The Journal of Physical Chemistry B 127 (21), 4746-4760, 2023
82023
Aberrant phase separation is a common killing strategy of positively charged peptides in biology and human disease
S Boeynaems, XR Ma, V Yeong, GM Ginell, JH Chen, JA Blum, ...
bioRxiv, 2023
72023
The formation of a fuzzy complex in the negative arm regulates the robustness of the circadian clock
MS Jankowski, D Griffith, DG Shastry, JF Pelham, GM Ginell, J Thomas, ...
bioRxiv, 2022.01. 04.474980, 2022
52022
SHEPHARD: a modular and extensible software architecture for analyzing and annotating large protein datasets
GM Ginell, AJ Flynn, AS Holehouse
Bioinformatics 39 (8), btad488, 2023
32023
Probing the hidden sensitivity of intrinsically disordered proteins to their chemical environment
D Moses, F Yu, GM Ginell, NM Shamoon, PS Koenig, AS Holehouse, ...
biorxiv, 2020.08. 17.252478, 2020
32020
Labile assembly of a tardigrade protein induces biostasis
S Sanchez-Martinez, K Nguyen, S Biswas, V Nicholson, AV Romanyuk, ...
bioRxiv, 2023.06. 30.547219, 2023
22023
Helicity of a tardigrade disordered protein promotes desiccation tolerance
S Biswas, E Gollub, F Yu, G Ginell, AS Holehouse, S Sukenik, TC Boothby
bioRxiv, 2023.07. 06.548010, 2023
12023
Disordered clock protein interactions and charge blocks turn an hourglass into a persistent circadian oscillator
MS Jankowski, D Griffith, DG Shastry, JF Pelham, GM Ginell, J Thomas, ...
Nature Communications 15 (1), 3523, 2024
2024
Helicity of a tardigrade disordered protein contributes to its protective function during desiccation
S Biswas, E Gollub, F Yu, G Ginell, A Holehouse, S Sukenik, TC Boothby
Protein Science 33 (2), e4872, 2024
2024
Intramolecular and intermolecular effects of aromatic sticker residue strength on intrinsically disordered protein regions
D Moses, GM Ginell, AS Holehouse, S Sukenik
Biophysical Journal 122 (3), 62a, 2023
2023
Understanding the Chemical Context of Interactions in Intrinsically Disordered Proteins
G Ginell
2023
Hyperphosphorylation tunes TDP‐43 solubility
GM Ginell, AS Holehouse
The EMBO Journal 41 (8), e111062, 2022
2022
A fuzzy complex in the negative arm regulates circadian clock robustness.
J Hurley, M Jankowski, D Griffith, D Shastry, J Pelham, G Ginell, J Thomas, ...
2022
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Articles 1–20