| Mendelian randomization study of PCSK9 and HMG-CoA reductase inhibition and cognitive function DB Rosoff, AS Bell, J Jung, J Wagner, LA Mavromatis, FW Lohoff Journal of the American College of Cardiology 80 (7), 653-662, 2022 | 44 | 2022 |
| Association Between Brain Structure and Alcohol Use Behaviors in Adults: A Mendelian Randomization and Multiomics Study LA Mavromatis, DB Rosoff, RB Cupertino, H Garavan, S Mackey, ... JAMA psychiatry 79 (9), 869-878, 2022 | 25 | 2022 |
| Additive effects of stress and alcohol exposure on accelerated epigenetic aging in alcohol use disorder J Jung, DL McCartney, J Wagner, J Yoo, AS Bell, LA Mavromatis, ... Biological Psychiatry 93 (4), 331-341, 2023 | 11 | 2023 |
| Comparing the Relationships of Genetically Proxied PCSK9 Inhibition With Mood Disorders, Cognition, and Dementia Between Men and Women: A Drug‐Target Mendelian Randomization Study AS Bell, DB Rosoff, LA Mavromatis, J Jung, J Wagner, FW Lohoff Journal of the American Heart Association 11 (21), e026122, 2022 | 11 | 2022 |
| Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging DB Rosoff, LA Mavromatis, AS Bell, J Wagner, J Jung, RE Marioni, ... Nature aging 3 (8), 1020-1035, 2023 | 7 | 2023 |
| Assessing the Impact of PCSK9 and HMGCR Inhibition on Liver Function: Drug-Target Mendelian Randomization Analyses in Four Ancestries DB Rosoff, AS Bell, J Wagner, LA Mavromatis, A Hamandi, L Park, J Jung, ... Cellular and Molecular Gastroenterology and Hepatology 17 (1), 29-40, 2024 | 4 | 2024 |
| Multi-omic underpinnings of epigenetic aging and human longevity LA Mavromatis, DB Rosoff, AS Bell, J Jung, J Wagner, FW Lohoff Nature Communications 14 (1), 2236, 2023 | 4 | 2023 |
| Multi-Omics Analyses of Cortical Proteome and Single Cell-Type Transcriptome Identifies Novel Drug Targets for Problematic Drinking Behavior and Alcohol Use Disorder D Rosoff, J Wagner, A Bell, L Mavromatis, J Jung, F Lohoff Biological Psychiatry 95 (10), S21, 2024 | | 2024 |
| PCSK9 inhibition attenuates alcohol-associated neuronal oxidative stress and cellular injury J Wagner, LM Park, P Mukhopadhyay, C Matyas, E Trojnar, R Damadzic, ... Brain, Behavior, and Immunity, 2024 | | 2024 |
| Evaluating the Cardiovascular Impact of Genetically Proxied PCSK9 and HMGCR Inhibition in East Asian and European Populations: A Drug-Target Mendelian Randomization Study DB Rosoff, AS Bell, LA Mavromatis, A Hamandi, L Park, J Jung, J Wagner, ... Circulation: Genomic and Precision Medicine 17 (1), e004224, 2024 | | 2024 |
| 62. A MENDELIAN RANDOMIZATION STUDY OF PROPROTEIN CONVERTASE SUBTILISIN KEXIN 9 INHIBITION AND STROKE: EVIDENCE FOR BENEFITS BEYOND LOW-DENSITY LIPOPROTEIN CHOLESTEROL LOWERING L Park, D Rosoff, L Mavromatis, A Bell, A Hamandi, J Jung, J Wagner, ... European Neuropsychopharmacology 75, S89, 2023 | | 2023 |
| Evaluating the hepatic efficacy and cardiometabolic profile of PNPLA3, TM6SF2, and other therapeutic targets for NALFD: a drug-target Mendelian randomization analysis D Rosoff, L Mavromatis, A Bell, A Hamandi, L Park, J Jung, J Wagner, ... Journal of Hepatology 78, S792-S793, 2023 | | 2023 |
| Novel Therapeutic Drug Target Discoveries for Alcohol Use Disorder and Problem Drinking: A Multi-Level Proteome-Wide Mendelian Randomization Study D Rosoff, J Wagner, A Bell, L Mavromatis, J Jung, F Lohoff Biological Psychiatry 93 (9), S30, 2023 | | 2023 |
| Stress and Alcohol Exposure Accelerate Epigenetic Aging J Jung, D McCartney, J Wagner, A Bell, L Mavromatis, D Rosoff, ... NEUROPSYCHOPHARMACOLOGY 47, 447-447, 2022 | | 2022 |
| Novel Underlying Biology and Therapeutic Targets for Alcohol Use Disorder and Problem Drinking Identified Using Proteomics and Mendelian Randomization D Rosoff, J Wagner, A Bell, L Mavromatis, J Jung, F Lohoff NEUROPSYCHOPHARMACOLOGY 47, 447-447, 2022 | | 2022 |
| A MULTIVARIABLE MENDELIAN RANDOMIZATION STUDY DISENTANGLING THE RELATIONSHIPS BETWEEN NEUROPSYCHIATRIC DISORDERS, SUBSTANCE USE BEHAVIORS, AND LONGEVITY D Rosoff, J Yoo, A Bell, L Mavromatis, J Jung, J Wagner, F Lohoff European Neuropsychopharmacology 63, e139, 2022 | | 2022 |
| P16. A Multivariable Mendelian Randomization Study Disentangling the Relationships Between Neuropsychiatric Disorders, Substance Use Behaviors, and Longevity D Rosoff, J Yoo, A Bell, L Mavromatis, J Jung, J Wagner, F Lohoff Biological Psychiatry 91 (9), S94, 2022 | | 2022 |
