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Dieudonné Buh Kum
Dieudonné Buh Kum
Aligos Therapeutics
Verified email at aligos.com
Title
Cited by
Cited by
Year
Zika virus replicons for drug discovery
X Xie, J Zou, C Shan, Y Yang, DB Kum, K Dallmeier, J Neyts, PY Shi
EBioMedicine 12, 156-160, 2016
902016
A single-dose live-attenuated Zika virus vaccine with controlled infection rounds that protects against vertical transmission
X Xie, DB Kum, H Xia, H Luo, C Shan, J Zou, AE Muruato, DBA Medeiros, ...
Cell host & microbe 24 (4), 487-499. e5, 2018
542018
A yellow fever–Zika chimeric virus vaccine candidate protects against Zika infection and congenital malformations in mice
DB Kum, N Mishra, R Boudewijns, I Gladwyn-Ng, C Alfano, J Ma, ...
npj Vaccines 3 (1), 56, 2018
442018
Capsid assembly modulators as antiviral agents against HBV: molecular mechanisms and clinical perspectives
V Taverniti, G Ligat, Y Debing, DB Kum, TF Baumert, ER Verrier
Journal of clinical medicine 11 (5), 1349, 2022
382022
A chimeric yellow fever-Zika virus vaccine candidate fully protects against yellow fever virus infection in mice
DB Kum, R Boudewijns, J Ma, N Mishra, D Schols, J Neyts, K Dallmeier
Emerging microbes & infections 9 (1), 520-533, 2020
222020
Limited evolution of the yellow fever virus 17d in a mouse infection model
DB Kum, N Mishra, B Vrancken, HJ Thibaut, A Wilder-Smith, P Lemey, ...
Emerging microbes & infections 8 (1), 1734-1746, 2019
192019
A high-throughput yellow fever neutralization assay
M Rasulova, T Vercruysse, J Paulissen, C Coun, V Suin, L Heyndrickx, ...
Microbiology Spectrum 10 (3), e02548-21, 2022
122022
Class a capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation
DB Kum, H Vanrusselt, AA Sanchez, V Taverniti, ER Verrier, TF Baumert, ...
Hepatology 78 (4), 1252-1265, 2023
72023
Comparing immunogenicity and protective efficacy of the yellow fever 17D vaccine in mice
J Ma, R Boudewijns, L Sanchez-Felipe, N Mishra, T Vercruysse, ...
Emerging Microbes & Infections 10 (1), 2279-2290, 2021
72021
ALG-005398 is a potent non-HAP class I HBV capsid assembly modulator that strongly reduces HBsAg levels in vivo
Y Debing, D Buh Kum, AA Sanchez, H Vanrusselt, C Liu, J Deval, ...
Hepatology 74, 502A-503A, 2021
32021
Best-In-Class Preclinical Characteristics of Alg-000184, A Prodrug of The Capsid Assembly Modulator Alg-001075 for the Treatment of Chronic Hepatitis B
Q Zhang, A Jekle, V Serebryany, M Welch, J Liu, S Vendeville, Y Debing, ...
The Liver Meeting Digital Experience™, 2020
32020
Capsid assembly modulator ALG-000111 and its prodrug ALG-000286 display excellent in vitro and in vivo antiviral activity
Y Debing, DB Kum, C Liu, J Deval, H Vanrusselt, AA Sanchez, Q Zhang, ...
Cell 500, 4, 2021
22021
Novel non-HAP class A HBV capsid assembly modulators have distinct in vitro and in vivo profiles
H Vanrusselt, DB Kum, V Taverniti, C Liu, A Acosta Sanchez, N Corthout, ...
Journal of Virology 97 (10), e00722-23, 2023
12023
Non-HAP class I capsid assembly modulators have distinct profiles and a differentiated mechanism of action
Y Debing, H Vanrusselt, D Buh Kum, A Acosta Sanchez, V Taverniti, ...
AASLD 2022, 2022
12022
An in vivo duck hepatitis B virus model recapitulates key aspects of nucleic acid polymer treatment outcomes in chronic hepatitis B patients
Y Debing, H Vanrusselt, L Degrauwe, DAS de Oliveira, CK Kariuki, ...
Antiviral Research, 105835, 2024
2024
PRECLINICAL RESISTANCE PROFILE AND ANTIVIRAL ACTIVITY OF THE BESTIN-CLASS CAM-E ALG-001075, THE PARENT COMPOUND OF ALG000184
Y Debing, AA Sanchez, H Vanrusselt, D Kum, L Degrauwe, TI Lin, ...
HEPATOLOGY 78, S583-S583, 2023
2023
CLASS A CAMS INDUCE CELL DEATH THROUGH HBV CORE PROTEIN AGGREGATION AND POTENTIALLY ACTIVATE THE INNATE IMMUNE RESPONSE
V Taverniti, H Vanrusselt, D Kum, Y Debing, ER Verrier, TF Baumert
HEPATOLOGY 78, S561-S562, 2023
2023
HAP Class I Capsid Assembly Modulators Clear Hepatitis B Virus-Infected Hepatocytes Through Core-dependent Hepatocyte Death and Subsequent Proliferation
DB Kum, H Vanrusselt, AA Sanchez, V Taverniti, ER Verrier, TF Baumert, ...
HEPATOLOGY 76, S313-S314, 2022
2022
Chimeric yellow fever ZIKA virus strain
K Dallmeier, DB Kum, N Mishra, J Neyts, MA Schmid
US Patent 11,351,240, 2022
2022
Chimeric Zika-Japanese Encephalitis Virus
K Dallmeier, DB Kum, N Mishra, J Neyts
US Patent App. 17/602,532, 2022
2022
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