Oxidative stress: The core pathogenesis and mechanism of Alzheimer’s disease R Bai, J Guo, XY Ye, Y Xie, T Xie Ageing research reviews 77, 101619, 2022 | 196 | 2022 |
Discovery of natural anti-inflammatory alkaloids: Potential leads for the drug discovery for the treatment of inflammation R Bai, C Yao, Z Zhong, J Ge, Z Bai, X Ye, T Xie, Y Xie European Journal of Medicinal Chemistry 213, 113165, 2021 | 92 | 2021 |
Design, synthesis, and biological evaluation of 1, 2, 4-triazole bearing 5-substituted biphenyl-2-sulfonamide derivatives as potential antihypertensive candidates J Liu, Q Liu, X Yang, S Xu, H Zhang, R Bai, H Yao, J Jiang, M Shen, X Wu, ... Bioorganic & medicinal chemistry 21 (24), 7742-7751, 2013 | 72 | 2013 |
Chemical approaches for the enhancement of porphyrin skeleton-based photodynamic therapy Y Lin, T Zhou, R Bai, Y Xie Journal of enzyme inhibition and medicinal chemistry 35 (1), 1080-1099, 2020 | 62 | 2020 |
Design, synthesis and biological evaluation of hydroxypyridinone-coumarin hybrids as multimodal monoamine oxidase B inhibitors and iron chelates against Alzheimer's disease C Zhang, K Yang, S Yu, J Su, S Yuan, J Han, Y Chen, J Gu, T Zhou, R Bai, ... European Journal of Medicinal Chemistry 180, 367-382, 2019 | 55 | 2019 |
Anti-tumor drug discovery based on natural product β-elemene: Anti-tumor mechanisms and structural modification Z Bai, C Yao, J Zhu, Y Xie, XY Ye, R Bai, T Xie Molecules 26 (6), 1499, 2021 | 50 | 2021 |
Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities X Jiang, K Wu, R Bai, P Zhang, Y Zhang European Journal of Medicinal Chemistry 229, 114085, 2022 | 46 | 2022 |
Medicinal chemistry updates of novel HDACs inhibitors (2020 to present) X He, Z Hui, L Xu, R Bai, Y Gao, Z Wang, T Xie, XY Ye European Journal of Medicinal Chemistry 227, 113946, 2022 | 46 | 2022 |
Current natural products with antihypertensive activity BAI Ren-Ren, WU Xiao-Ming, XU Jin-Yi Chinese journal of natural medicines 13 (10), 721-729, 2015 | 46 | 2015 |
Discovery of novel tacrine–pyrimidone hybrids as potent dual AChE/GSK-3 inhibitors for the treatment of Alzheimer’s disease H Yao, G Uras, P Zhang, S Xu, Y Yin, J Liu, S Qin, X Li, S Allen, R Bai, ... Journal of Medicinal Chemistry 64 (11), 7483-7506, 2021 | 44 | 2021 |
Natural terpenoids with anti-inflammatory activities: Potential leads for anti-inflammatory drug discovery J Ge, Z Liu, Z Zhong, L Wang, X Zhuo, J Li, X Jiang, XY Ye, T Xie, R Bai Bioorganic Chemistry 124, 105817, 2022 | 42 | 2022 |
Hydroxypyridinone-based iron chelators with broad-ranging biological activities X Jiang, T Zhou, R Bai, Y Xie Journal of Medicinal Chemistry 63 (23), 14470-14501, 2020 | 38 | 2020 |
Coordinating Activation Strategy‐Induced Selective C− H Trifluoromethylation of Anilines J Xu, K Cheng, C Shen, R Bai, Y Xie, P Zhang ChemCatChem 10 (5), 965-970, 2018 | 38 | 2018 |
Synthesis and biological evaluation of 4′-[(benzimidazole-1-yl) methyl] biphenyl-2-sulfonamide derivatives as dual angiotensin II/endothelin A receptor antagonists R Bai, Z Wei, J Liu, W Xie, H Yao, X Wu, J Jiang, Q Wang, J Xu Bioorganic & medicinal chemistry 20 (15), 4661-4667, 2012 | 37 | 2012 |
Heck reaction prediction using a transformer model based on a transfer learning strategy L Wang, C Zhang, R Bai, J Li, H Duan Chemical Communications 56 (65), 9368-9371, 2020 | 35 | 2020 |
Design, synthesis and antioxidant activity evaluation of novel β-elemene derivatives J Chen, W Duan, R Bai, H Yao, J Shang, J Xu Bioorganic & Medicinal Chemistry Letters 24 (15), 3407-3411, 2014 | 35 | 2014 |
Total synthesis and antihypertensive activity of (±) 7, 8-dihydroxy-3-methyl-isochromanone-4 J Liu, H Ren, J Xu, R Bai, Q Yan, W Huang, X Wu, J Fu, Q Wang, Q Wu, ... Bioorganic & medicinal chemistry letters 19 (6), 1822-1824, 2009 | 33 | 2009 |
Rational design, synthesis and biological evaluation of novel multitargeting anti-AD iron chelators with potent MAO-B inhibitory and antioxidant activity X Jiang, J Guo, Y Lv, C Yao, C Zhang, Z Mi, Y Shi, J Gu, T Zhou, R Bai, ... Bioorganic & Medicinal Chemistry 28 (12), 115550, 2020 | 29 | 2020 |
Discovery of small-molecule candidates against inflammatory bowel disease R Bai, X Jie, C Yao, Y Xie European journal of medicinal chemistry 185, 111805, 2020 | 29 | 2020 |
Dual-target anti-Alzheimer’s disease agents with both iron ion chelating and monoamine oxidase-B inhibitory activity Z Mi, B Gan, S Yu, J Guo, C Zhang, X Jiang, T Zhou, J Su, R Bai, Y Xie Journal of enzyme inhibition and medicinal chemistry 34 (1), 1489-1497, 2019 | 29 | 2019 |