Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice Y Li, RM Ritzel, N Khan1, T Cao, J He, Z Lei, JJ Matyas, B Sabirzhanov, ... Theranostics 10 (25), 11376-11403, 2020 | 114 | 2020 |
Chemical conversion of human fetal astrocytes into neurons through modulation of multiple signaling pathways JC Yin, L Zhang, NX Ma, Y Wang, G Lee, XY Hou, ZF Lei, FY Zhang, ... Stem Cell Reports 12 (3), 488-501, 2019 | 86 | 2019 |
Regeneration of functional neurons after spinal cord injury via in situ NeuroD1-mediated astrocyte-to-neuron conversion HL Gong Chen, Brendan Puls, Yan Ding, Fengyu Zhang, Mengjie Pan, Zhuofan Lei ... Frontiers Cell and Developmental Biology, 2020 | 75 | 2020 |
mGluR1,5 activation improves network asynchrony and GABAergic synapse attenuation in the amygdala: implication for anxiety-like behavior in DBA/2 mice F Zhang, B Liu, Z Lei, JH Wang Molecular Brain 5, 1-13, 2012 | 61 | 2012 |
Neurons in the barrel cortex turn into processing whisker and odor signals: a cellular mechanism for the storage and retrieval of associative signals D Wang, J Zhao, Z Gao, N Chen, B Wen, W Lu, Z Lei, C Chen, Y Liu, ... Frontiers in Cellular Neuroscience 9, 320, 2015 | 51 | 2015 |
Development of Neuroregenerative Gene Therapy to Reverse Glial Scar Tissue Back to Neuron-Enriched Tissue 2* Lei Zhang1†, Zhuofan Lei1†, Ziyuan Guo1, Zifei Pei1, Yuchen Chen1, Fengyu ... Frontiers in Cellular Neuroscience, 2020 | 45 | 2020 |
Impairment of autophagy after spinal cord injury potentiates neuroinflammation and motor function deficit in mice Y Li, Z Lei, RM Ritzel, J He, H Li, HMC Choi, MM Lipinski, J Wu Theranostics 12 (12), 5364, 2022 | 34 | 2022 |
Reversing glial scar back to neural tissue through NeuroD1-mediated astrocyte-to-neuron conversion L Zhang, Z Lei, Z Guo, Z Pei, Y Chen, F Zhang, A Cai, YK Mok, G Lee, ... BioRxiv, 261438, 2018 | 24 | 2018 |
Functional and transcriptional profiling of microglial activation during the chronic phase of TBI identifies an age-related driver of poor outcome in old mice RM Ritzel, Y Li, Z Lei, J Carter, J He, HMC Choi, N Khan, H Li, S Allen, ... Geroscience 44 (3), 1407-1440, 2022 | 23 | 2022 |
Sexual dimorphism in neurological function after SCI is associated with disrupted neuroinflammation in both injured spinal cord and brain Y Li, RM Ritzel, Z Lei, T Cao, J He, AI Faden, J Wu Brain, behavior, and immunity 101, 1-22, 2022 | 23 | 2022 |
Brain injury accelerates the onset of a reversible age-related microglial phenotype associated with inflammatory neurodegeneration RM Ritzel, Y Li, Y Jiao, Z Lei, SJ Doran, J He, RA Shahror, RJ Henry, ... Science Advances 9 (10), eadd1101, 2023 | 22 | 2023 |
Synapse innervation and associative memory cell are recruited for integrative storage of whisker and odor signals in the barrel cortex through miRNA-mediated processes Z Lei, D Wang, N Chen, K Ma, W Lu, Z Song, S Cui, JH Wang Frontiers in cellular neuroscience 11, 316, 2017 | 22 | 2017 |
Reward memory relieves anxiety‐related behavior through synaptic strengthening and protein kinase C in dentate gyrus Z Lei, B Liu, JH Wang Hippocampus 26 (4), 502-516, 2016 | 12 | 2016 |
Regeneration of dorsal spinal cord neurons after injury via in situ NeuroD1-mediated astrocyte-to-neuron conversion B Puls, Y Ding, F Zhang, M Pan, Z Lei, Z Pei, M Jiang, Y Bai, C Forsyth, ... BioRxiv, 818823, 2019 | 6 | 2019 |
Traumatic brain injury-induced inflammatory changes in the olfactory bulb disrupt neuronal networks leading to olfactory dysfunction X Liu, Z Lei, D Gilhooly, J He, Y Li, RM Ritzel, H Li, LJ Wu, S Liu, J Wu Brain, Behavior, and Immunity 114, 22-45, 2023 | 4 | 2023 |
Sexually dimorphic extracellular vesicle responses after chronic spinal cord injury are associated with neuroinflammation and neurodegeneration in the aged brain Y Li, N Khan, RM Ritzel, Z Lei, S Allen, AI Faden, J Wu Journal of Neuroinflammation 20 (1), 197, 2023 | 3 | 2023 |
Age-related dysregulation of autophagy contributes to microglial dysfunction and chronic neurobehavioral deficits after traumatic brain injury R Ritzel, Y Li, Z Lei, J Carter, J He, H Choi, N Khan, H Li, S Allen, ... | 2 | 2021 |
Stem Cell Reports Chemical Conversion of Human Fetal Astrocytes into Neurons through Modulation of Multiple Signaling Pathways JC Yin, L Zhang, NX Ma, Y Wang, G Lee, XY Hou, ZF Lei, FY Zhang, ... | 2 | 2019 |
Age-related changes in plasma extracellular vesicles influence neuroinflammation in the brain and neurological outcome after traumatic spinal cord injury Z Lei, B Krishnamachary, RM Ritzel, NZ Khan, Y Li, H Li, K Brunner, ... Research Square, 2023 | 1 | 2023 |
Brain repair after traumatic brain injury through neurod1-mediated astrocyte-to-neuron conversion G Chen, ZF Lei US Patent App. 17/105,022, 2022 | 1 | 2022 |