Randy Y.C. Poon
Randy Y.C. Poon
Chair Professor, Division of Life Science, The Hong Kong University of Science and Technology
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Cyclin A in cell cycle control and cancer
CH Yam, TK Fung, RYC Poon
Cellular and Molecular Life Sciences CMLS 59, 1317-1326, 2002
The cdc2‐related protein p40MO15 is the catalytic subunit of a protein kinase that can activate p33cdk2 and p34cdc2.
RY Poon, K Yamashita, JP Adamczewski, T Hunt, J Shuttleworth
The EMBO Journal 12 (8), 3123-3132, 1993
Cyclin-dependent kinases and S phase control in mammalian cells
RA Woo, RYC Poon
Cell cycle 2 (4), 315-323, 2003
On the synthesis and destruction of A-and B-type cyclins during oogenesis and meiotic maturation in Xenopus laevis.
H Kobayashi, J Minshull, C Ford, R Golsteyn, R Poon, T Hunt
The Journal of Cell Biology 114 (4), 755-765, 1991
Identification of the domains in cyclin A required for binding to, and activation of, p34cdc2 and p32cdk2 protein kinase subunits.
H Kobayashi, E Stewart, R Poon, JP Adamczewski, J Gannon, T Hunt
Molecular Biology of the Cell 3 (11), 1279-1294, 1992
Redistribution of the CDK inhibitor p27 between different cyclin. CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation.
RY Poon, H Toyoshima, T Hunter
Molecular Biology of the Cell 6 (9), 1197-1213, 1995
A roller coaster ride with the mitotic cyclins
TK Fung, RYC Poon
Seminars in cell & developmental biology 16 (3), 335-342, 2005
Dephosphorylation of Cdk2 Thr160 by the cyclin-dependent kinase-interacting phosphatase KAP in the absence of cyclin
RYC Poon, T Hunter
Science 270 (5233), 90-93, 1995
Involvement of p21 and p27 in the regulation of CDK activity and cell cycle progression in the regenerating liver
JH Albrecht, RYC Poon, CL Ahonen, BM Rieland, C Deng, GS Crary
Oncogene 16 (16), 2141-2150, 1998
Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage
RYC Poon, W Jiang, H Toyoshima, T Hunter
Journal of Biological Chemistry 271 (22), 13283-13291, 1996
How many mutant p53 molecules are needed to inactivate a tetramer?
WM Chan, WY Siu, A Lau, RYC Poon
Molecular and cellular biology 24 (8), 3536-3551, 2004
Inactivation of p27Kip1 by the viral E1A oncoprotein in TGFβ-treated cells
A Mal, RYC Poon, PH Howe, H Toyoshima, T Hunter, ML Harter
Nature 380 (6571), 262-265, 1996
The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells
RYC Poon, MS Chau, K Yamashita, T Hunter
Cancer Research 57 (22), 5168-5178, 1997
MDM2 and MDMX bind and stabilize the p53-related protein p73
WM Ongkeko, XQ Wang, WY Siu, AWS Lau, K Yamashita, AL Harris, ...
Current biology 9 (15), 829-832, 1999
Identification of functional domains in the neuronal Cdk5 activator protein
RYC Poon, J Lew, T Hunter
Journal of Biological Chemistry 272 (9), 5703-5708, 1997
Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation
RA Woo, RYC Poon
Genes & development 18 (11), 1317-1330, 2004
The multiple checkpoint functions of CHK1 and CHK2 in maintenance of genome stability
Y Chen, RYC Poon
Frontiers in Bioscience-Landmark 13 (13), 5016-5029, 2008
The candidate tumor suppressor ING1b can stabilize p53 by disrupting the regulation of p53 by MDM2
KM Leung, LS Po, FC Tsang, WY Siu, A Lau, HTB Ho, RYC Poon
Cancer research 62 (17), 4890-4893, 2002
Cdc37: a protein kinase chaperone?
T Hunter, RYC Poon
Trends in cell biology 7 (4), 157-161, 1997
Specialized roles of the two mitotic cyclins in somatic cells: Cyclin A as an activator of M phase–promoting factor
TK Fung, HT Ma, RYC Poon
Molecular biology of the cell 18 (5), 1861-1873, 2007
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