MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling N Mellios, DA Feldman, SD Sheridan, JPK Ip, S Kwok, SK Amoah, ... Molecular psychiatry 23 (4), 1051-1065, 2018 | 233 | 2018 |
Genome editing of lineage determinants in human pluripotent stem cells reveals mechanisms of pancreatic development and diabetes Z Zhu, QV Li, K Lee, BP Rosen, F González, CL Soh, D Huangfu Cell stem cell 18 (6), 755-768, 2016 | 182 | 2016 |
Genome-scale screens identify JNK–JUN signaling as a barrier for pluripotency exit and endoderm differentiation QV Li, G Dixon, N Verma, BP Rosen, M Gordillo, R Luo, C Xu, Q Wang, ... Nature genetics 51 (6), 999-1010, 2019 | 101 | 2019 |
QSER1 protects DNA methylation valleys from de novo methylation G Dixon, H Pan, D Yang, BP Rosen, T Jashari, N Verma, J Pulecio, ... Science 372 (6538), eabd0875, 2021 | 76 | 2021 |
Sphingosine kinase 1 is regulated by peroxisome proliferator-activated receptor α in response to free fatty acids and is essential for skeletal muscle interleukin-6 production … JS Ross, W Hu, B Rosen, AJ Snider, LM Obeid, LA Cowart Journal of Biological Chemistry 288 (31), 22193-22206, 2013 | 54 | 2013 |
Glutamine independence is a selectable feature of pluripotent stem cells SA Vardhana, PK Arnold, BP Rosen, Y Chen, BW Carey, D Huangfu, ... Nature metabolism 1 (7), 676-687, 2019 | 49 | 2019 |
CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction D Yang, H Cho, Z Tayyebi, A Shukla, R Luo, G Dixon, V Ursu, S Stransky, ... Nature cell biology 24 (7), 1064-1076, 2022 | 20 | 2022 |
Human cerebral organoids reveal deficits in neurogenesis and neuronal migration in MeCP2-deficient neural progenitors N Mellios, DA Feldman, SD Sheridan, JPK Ip, S Kwok, SK Amoah, ... Molecular Psychiatry 23 (4), 791-791, 2018 | 14 | 2018 |
Decoding pluripotency: Genetic screens to interrogate the acquisition, maintenance, and exit of pluripotency QV Li, BP Rosen, D Huangfu Wiley Interdisciplinary Reviews: Systems Biology and Medicine 12 (1), e1464, 2020 | 12 | 2020 |
Dynamic network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer gene regulatory activity during cell state transitions R Luo, J Yan, JW Oh, W Xi, D Shigaki, W Wong, HS Cho, D Murphy, ... Nature genetics 55 (8), 1336-1346, 2023 | 10* | 2023 |
Gonza ́ lez, F., Soh, C.-L. and Huangfu, D.(2016). Genome editing of lineage determinants in human pluripotent stem cells reveals mechanisms of pancreatic development and diabetes Z Zhu, QV Li, K Lee, BP Rosen Cell Stem Cell 18, 755-768, 0 | 7 | |
Parallel genome-scale CRISPR screens distinguish pluripotency and self-renewal BP Rosen, QV Li, H Cho, D Liu, D Yang, S Graff, J Yan, R Luo, N Verma, ... bioRxiv, 2023.05. 03.539283, 2023 | 1 | 2023 |
Sphingosine kinase 1 is regulated by PPARalpha in response to free fatty acids and is essential for skeletal muscle IL-6 production and signaling in diet-induced obesity JS Ross, W Hu, B Rosen, AJ Snider, LM Obeid, LA Cowart J. Biol. Chem 288, 22193-22206, 2013 | 1 | 2013 |
Decoding Heterogenous Single-cell Perturbation Responses B Song, D Liu, W Dai, N McMyn, Q Wang, D Yang, A Krejci, A Vasilyev, ... bioRxiv, 2023 | | 2023 |
Uncovering Regulators of Human Pluripotency Using Comparative CRISPR Screening B Rosen Weill Medical College of Cornell University, 2023 | | 2023 |
Sphingosine Kinase 1 is regulated by PPARα in response to free fatty acids and mediates skeletal muscle IL‐6 production and signaling in diet‐induced obesity JS Ross, W Hu, B Rosen, AJ Snider, LM Obeid, LA Cowart The FASEB Journal 27, 813.18-813.18, 2013 | | 2013 |