Analysis of tumor-infiltrating NK and T cells highlights IL-15 stimulation and TIGIT blockade as a combination immunotherapy strategy for soft tissue sarcomas SJ Judge, MA Darrow, SW Thorpe, AA Gingrich, EF O'Donnell, AR Bellini, ... Journal for immunotherapy of cancer 8 (2), 2020 | 77 | 2020 |
PD-1 blockade reverses obesity-mediated T cell priming impairment CT Le, LT Khuat, SE Caryotakis, M Wang, C Dunai, AV Nguyen, LV Vick, ... Frontiers in immunology 11, 590568, 2020 | 12 | 2020 |
Increased efficacy of dual proinflammatory cytokine blockade on acute GVHD while maintaining GVT effects LT Khuat, LV Vick, C Dunai, CP Collins, SK More, CT Le, CCS Pai, ... Blood, The Journal of the American Society of Hematology 138 (24), 2583-2588, 2021 | 9 | 2021 |
Mechanisms by Which Obesity Promotes Acute Graft-Versus-Host Disease in Mice LT Khuat, LV Vick, E Choi, C Dunai, AA Merleev, E Maverakis, BR Blazar, ... Frontiers in immunology 12, 752484, 2021 | 9 | 2021 |
Atezolizumab plus stereotactic ablative radiotherapy for medically inoperable patients with early-stage non-small cell lung cancer: a multi-institutional phase I trial AM Monjazeb, ME Daly, G Luxardi, E Maverakis, AA Merleev, AI Marusina, ... Nature Communications 14 (1), 5332, 2023 | 6 | 2023 |
Aging augments obesity-induced thymic involution and peripheral T cell exhaustion altering the “obesity paradox” LV Vick, CP Collins, LT Khuat, Z Wang, C Dunai, EG Aguilar, K Stoffel, ... Frontiers in immunology 13, 1012016, 2023 | 5 | 2023 |
Transcriptome analysis of tumor-infiltrating lymphocytes identifies NK cell gene signatures associated with lymphocyte infiltration and survival in soft tissue sarcomas SJ Judge, JD Bloomstein, CJ Sholevar, MA Darrow, KM Stoffel, LV Vick, ... Frontiers in immunology 13, 893177, 2022 | 5 | 2022 |
Multifaceted effects of obesity on cancer immunotherapies: bridging preclinical models and clinical data LV Vick, RJ Canter, AM Monjazeb, WJ Murphy Seminars in cancer biology, 2023 | 4 | 2023 |
Mouse preclinical cancer immunotherapy modeling involving anti-PD-1 therapies reveals the need to use mouse reagents to mirror clinical paradigms AM Monjazeb, Z Wang, LV Vick, C Dunai, C Minnar, LT Khuat, WJ Murphy Cancers 13 (4), 729, 2021 | 4 | 2021 |
534 Sex-linked differences in obesity markedly impact the anti-tumor efficacy of PD-1 blockade L Vick, Z Wang, C Collins, L Khuat, C Dunai, K Stoffel, S Yendamuri, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | 1 | 2022 |
Activation status dictates the function of unlicensed natural killer cells in mice and humans EG Aguilar, C Dunai, SJ Judge, AE Zamora, LT Khuat, LV Vick, CP Collins, ... Blood advances 5 (20), 4219-4232, 2021 | 1 | 2021 |
Differences in NK and Memory CD8 T cell responses to antigen-nonspecific stimulation by interleukin-15 SJ Judge, C Dunai, CT Le, LT Khuat, LV Vick, KM Stoffel, AM Monjazeb, ... The Journal of Immunology 204 (1_Supplement), 148.17-148.17, 2020 | 1 | 2020 |
Potential roles of sex-linked differences in obesity and cancer immunotherapy: revisiting the obesity paradox LV Vick, S Rosario, JW Riess, RJ Canter, S Mukherjee, AM Monjazeb, ... npj Metabolic Health and Disease 2 (1), 5, 2024 | | 2024 |
Abstract SY38-01: Diverse effects of obesity on cancer immunology and therapy: Both the good and the bad WJ Murphy, L Vick, R Canter, S Rosario, A Monjazeb Cancer Research 84 (7_Supplement), SY38-01-SY38-01, 2024 | | 2024 |
Tumor Resistance to Fractionated Radiotherapy in Obese Mice LV Vick, D Yoon, JR Perks, JJ Li, WJ Murphy, AM Monjazeb International Journal of Radiation Oncology, Biology, Physics 117 (2), S139, 2023 | | 2023 |
Regulation of human and mouse bystander T cell activation responses by PD-1 CT Le, LV Vick, C Collins, C Dunai, MK Sheng, LT Khuat, I Barao, ... JCI insight 8 (18), 2023 | | 2023 |
Asymmetrical Expression of PD1 and CD25 in T-cells Post-Initial Activation MK Sheng, L Vick, C Collins, DJ Yoon, WJ Murphy The Journal of Immunology 210 (1_Supplement), 226.18-226.18, 2023 | | 2023 |
PD-1 signaling serves a dual role in suppressing T cell activation but also in protecting from activation-induced cell death LV Vick, LT Khuat, C Le, C Dunai, C Collins, R Canter, A Monjazeb, ... The Journal of Immunology 210 (1_Supplement), 226.11-226.11, 2023 | | 2023 |
Inhibitory Receptor TIGIT is a critical regulator of Natural Killer Cell Activation and Survival Following Strong Stimulation ML Lammers, S Judge, RN Nielsen, L Farley, K Iranpur, MK Sheng, L Vick, ... The Journal of Immunology 210 (1_Supplement), 244.06-244.06, 2023 | | 2023 |
Systemic Cancer Immunostimulatory Therapies and Acute Viral Infection Induce Corticosteroid-Mediated Thymic Involution and Naïve T cell Output in Mice and Humans DJ Yoon, LT Khuat, C Collins, L Vick, G Sckisel, CM Minnar, C Dunai, ... The Journal of Immunology 210 (1_Supplement), 145.21-145.21, 2023 | | 2023 |