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Chelsea E Powell
Chelsea E Powell
Postdoctoral Fellow, Harvard Medical School
Verified email at hms.harvard.edu
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Cited by
Cited by
Year
Chemically induced degradation of anaplastic lymphoma kinase (ALK)
CE Powell, Y Gao, L Tan, KA Donovan, RP Nowak, A Loehr, M Bahcall, ...
Journal of medicinal chemistry 61 (9), 4249-4255, 2018
1852018
SRPKIN-1: a covalent SRPK1/2 inhibitor that potently converts VEGF from pro-angiogenic to anti-angiogenic isoform
JM Hatcher, G Wu, C Zeng, J Zhu, F Meng, S Patel, W Wang, SB Ficarro, ...
Cell chemical biology 25 (4), 460-470. e6, 2018
1132018
Selective degradation of GSPT1 by cereblon modulators identified via a focused combinatorial library
CE Powell, G Du, J Che, Z He, KA Donovan, H Yue, ES Wang, RP Nowak, ...
ACS chemical biology 15 (10), 2722-2730, 2020
622020
A gut-restricted lithocholic acid analog as an inhibitor of gut bacterial bile salt hydrolases
AA Adhikari, D Ramachandran, SN Chaudhari, CE Powell, W Li, ...
ACS Chemical Biology 16 (8), 1401-1412, 2021
272021
Selective degradation-inducing probes for studying cereblon (CRBN) biology
CE Powell, G Du, JW Bushman, Z He, T Zhang, ES Fischer, NS Gray
RSC Medicinal Chemistry 12 (8), 1381-1390, 2021
182021
Benzopyrimidodiazepinone inhibitors of TNK2
BJ Groendyke, CE Powell, F Feru, TW Gero, Z Li, H Szabo, K Pang, ...
Bioorganic & Medicinal Chemistry Letters 30 (4), 126948, 2020
82020
Selective Macrocyclic Inhibitors of DYRK1A/B
CE Powell, JM Hatcher, J Jiang, PS Vatsan, J Che, NS Gray
ACS Medicinal Chemistry Letters 13 (4), 577-585, 2022
52022
Discovery of a series of benzopyrimidodiazepinone TNK2 inhibitors via scaffold morphing
Z Li, CE Powell, BJ Groendyke, TW Gero, F Feru, J Feutrill, B Chen, B Li, ...
Bioorganic & Medicinal Chemistry Letters 30 (19), 127456, 2020
42020
From Probes to Therapeutics: Chemical Biology Studies of Anaplastic Lymphoma Kinase (ALK) and Cereblon
CE Powell
2020
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Articles 1–9