Chemically induced degradation of anaplastic lymphoma kinase (ALK) CE Powell, Y Gao, L Tan, KA Donovan, RP Nowak, A Loehr, M Bahcall, ... Journal of medicinal chemistry 61 (9), 4249-4255, 2018 | 185 | 2018 |
SRPKIN-1: a covalent SRPK1/2 inhibitor that potently converts VEGF from pro-angiogenic to anti-angiogenic isoform JM Hatcher, G Wu, C Zeng, J Zhu, F Meng, S Patel, W Wang, SB Ficarro, ... Cell chemical biology 25 (4), 460-470. e6, 2018 | 113 | 2018 |
Selective degradation of GSPT1 by cereblon modulators identified via a focused combinatorial library CE Powell, G Du, J Che, Z He, KA Donovan, H Yue, ES Wang, RP Nowak, ... ACS chemical biology 15 (10), 2722-2730, 2020 | 62 | 2020 |
A gut-restricted lithocholic acid analog as an inhibitor of gut bacterial bile salt hydrolases AA Adhikari, D Ramachandran, SN Chaudhari, CE Powell, W Li, ... ACS Chemical Biology 16 (8), 1401-1412, 2021 | 27 | 2021 |
Selective degradation-inducing probes for studying cereblon (CRBN) biology CE Powell, G Du, JW Bushman, Z He, T Zhang, ES Fischer, NS Gray RSC Medicinal Chemistry 12 (8), 1381-1390, 2021 | 18 | 2021 |
Benzopyrimidodiazepinone inhibitors of TNK2 BJ Groendyke, CE Powell, F Feru, TW Gero, Z Li, H Szabo, K Pang, ... Bioorganic & Medicinal Chemistry Letters 30 (4), 126948, 2020 | 8 | 2020 |
Selective Macrocyclic Inhibitors of DYRK1A/B CE Powell, JM Hatcher, J Jiang, PS Vatsan, J Che, NS Gray ACS Medicinal Chemistry Letters 13 (4), 577-585, 2022 | 5 | 2022 |
Discovery of a series of benzopyrimidodiazepinone TNK2 inhibitors via scaffold morphing Z Li, CE Powell, BJ Groendyke, TW Gero, F Feru, J Feutrill, B Chen, B Li, ... Bioorganic & Medicinal Chemistry Letters 30 (19), 127456, 2020 | 4 | 2020 |
From Probes to Therapeutics: Chemical Biology Studies of Anaplastic Lymphoma Kinase (ALK) and Cereblon CE Powell | | 2020 |